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• W2022295527 endingPage "1888" @default.
• W2022295527 startingPage "1888" @default.
• W2022295527 abstract "Biotic and abiotic stresses adversely affect agriculture by reducing crop growth and productivity worldwide. To investigate the abiotic stress-responsive genes in Arabidopsis thaliana, we compiled a dataset of stress signals and differentially upregulated genes (>= 2.5 fold change) from Stress-responsive transcription Factors DataBase (STIFDB) with additional set of stress signals and genes curated from PubMed and Gene Expression Omnibus. A dataset of 3091 genes differentially upregulated due to 14 different stress signals (abscisic acid, aluminum, cold, cold–drought–salt, dehydration, drought, heat, iron, light, NaCl, osmotic stress, oxidative stress, UV-B and wounding) were curated and used for the analysis. Details about stress-responsive enriched genes and their association with stress signals can be obtained from STIFDB2 database http://caps.ncbs.res.in/stifdb2. The gene–stress-signal data were analyzed using an enrichment-based meta-analysis framework consisting of two different ontologies (Gene Ontology and Plant Ontology), biological pathway and functional domain annotations. We found several shared and distinct biological processes, cellular components and molecular functions associated with stress-responsive genes. Pathway analysis revealed that stress-responsive genes perturbed the pathways under the “Metabolic pathways” category. We also found several shared and stress-signal specific protein domains, suggesting functional mechanisms regulating stress-response. Phenomic characteristics of abiotic stress-responsive genes were ascertained for several stresses and found to be shared by multiple stresses in both anatomy and temporal categories of Plant Ontology. We found several constitutive stress-responsive genes that are differentially upregulated due to perturbation of different stress signals, for example a gene (AT1G68440) involved in phenylpropanoid metabolism and polyamine catabolism as responsive to seven different stress signals. We also performed structure–function prediction of five genes associated responsive to multiple abiotic stress signals. We envisage that results from our analysis that provide insight into functional repertoire, metabolic pathways and phenomic characteristics common and specifically associated with stress signals would help to understand abiotic stress regulome in Arabidopsis thaliana and may also help to develop an improved plant variety using molecular breeding and genetic engineering techniques that are rapidly stress-responsive and tolerant." @default.
• W2022295527 created "2016-06-24" @default.
• W2022295527 creator A5006145669 @default.
• W2022295527 creator A5016416266 @default.
• W2022295527 creator A5076779054 @default.
• W2022295527 date "2013-01-01" @default.
• W2022295527 modified "2023-10-03" @default.
• W2022295527 title "Comparative analyses of stress-responsive genes in Arabidopsis thaliana: insight from genomic data mining, functional enrichment, pathway analysis and phenomics" @default.
• W2022295527 cites W110585086 @default.
• W2022295527 cites W1500274797 @default.
• W2022295527 cites W1524141331 @default.
• W2022295527 cites W1964211527 @default.
• W2022295527 cites W1969353942 @default.
• W2022295527 cites W1972486925 @default.
• W2022295527 cites W1973424926 @default.
• W2022295527 cites W1982724915 @default.
• W2022295527 cites W1985630686 @default.
• W2022295527 cites W1988086016 @default.
• W2022295527 cites W1990642425 @default.
• W2022295527 cites W1992165465 @default.
• W2022295527 cites W1994130992 @default.
• W2022295527 cites W1995811913 @default.
• W2022295527 cites W1998767819 @default.
• W2022295527 cites W2007123820 @default.
• W2022295527 cites W2008693869 @default.
• W2022295527 cites W2012159938 @default.
• W2022295527 cites W2020541351 @default.
• W2022295527 cites W2021681326 @default.
• W2022295527 cites W2025092135 @default.
• W2022295527 cites W2030679236 @default.
• W2022295527 cites W2032663499 @default.
• W2022295527 cites W2033398667 @default.
• W2022295527 cites W2036407878 @default.
• W2022295527 cites W2040527293 @default.
• W2022295527 cites W2051618308 @default.
• W2022295527 cites W2053427298 @default.
• W2022295527 cites W2053604524 @default.
• W2022295527 cites W2053874089 @default.
• W2022295527 cites W2057064068 @default.
• W2022295527 cites W2060259273 @default.
• W2022295527 cites W2063344963 @default.
• W2022295527 cites W2065480641 @default.
• W2022295527 cites W2069211259 @default.
• W2022295527 cites W2069624025 @default.
• W2022295527 cites W2070923407 @default.
• W2022295527 cites W2077394023 @default.
• W2022295527 cites W2077438398 @default.
• W2022295527 cites W2078611593 @default.
• W2022295527 cites W2081501649 @default.
• W2022295527 cites W2082123301 @default.
• W2022295527 cites W2085587146 @default.
• W2022295527 cites W2086330580 @default.
• W2022295527 cites W2087210253 @default.
• W2022295527 cites W2088393334 @default.
• W2022295527 cites W2091940856 @default.
• W2022295527 cites W2094678200 @default.
• W2022295527 cites W2095811247 @default.
• W2022295527 cites W2097311303 @default.
• W2022295527 cites W2098758691 @default.
• W2022295527 cites W2099742755 @default.
• W2022295527 cites W2100701178 @default.
• W2022295527 cites W2101814492 @default.
• W2022295527 cites W2102633756 @default.
• W2022295527 cites W2102634667 @default.
• W2022295527 cites W2103391693 @default.
• W2022295527 cites W2104417055 @default.
• W2022295527 cites W2108649941 @default.
• W2022295527 cites W2109538083 @default.
• W2022295527 cites W2110595429 @default.
• W2022295527 cites W2111841128 @default.
• W2022295527 cites W2112767859 @default.
• W2022295527 cites W2113142309 @default.
• W2022295527 cites W2115202043 @default.
• W2022295527 cites W2116211027 @default.
• W2022295527 cites W2116808860 @default.
• W2022295527 cites W2119067812 @default.
• W2022295527 cites W2119076469 @default.
• W2022295527 cites W2123073741 @default.
• W2022295527 cites W2124922304 @default.
• W2022295527 cites W2126623160 @default.
• W2022295527 cites W2128224069 @default.
• W2022295527 cites W2130410032 @default.
• W2022295527 cites W2130499440 @default.
• W2022295527 cites W2133408621 @default.
• W2022295527 cites W2133465414 @default.
• W2022295527 cites W2133812171 @default.
• W2022295527 cites W2134375320 @default.
• W2022295527 cites W2135230723 @default.
• W2022295527 cites W2135773311 @default.
• W2022295527 cites W2135896045 @default.
• W2022295527 cites W2135912076 @default.
• W2022295527 cites W2137529106 @default.
• W2022295527 cites W2140717961 @default.
• W2022295527 cites W2141971234 @default.
• W2022295527 cites W2146805707 @default.
• W2022295527 cites W2147059525 @default.
• W2022295527 cites W2148032599 @default.
• W2022295527 cites W2149583752 @default.

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