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• W2022302274 abstract "Abstract Arbacia punctulata eggs were irradiated with low level laser energy (3.2 millijoules (mJ)/cm 2 for 500 μsec) before fertilization. The zygotes and early embryos were observed in order to detect developmental changes and alterations in DNA synthesis. No microscopic changes occurred in the eggs after irradiation, but many developmental abnormalities, similar to those produced by cytotoxic or metabolic agents, appeared after fertilization. A moderate degree of asynchrony was also detected in irradiated populations. Synthesis of DNA (S phase) was determined by using tritiated thymidine and scintillation counting techniques. The low level laser irradiation produced a pronounced delay in post-fertilization DNA synthesis. The onset of the first synthetic period was delayed approximately twice as long as the control. The delay continued throughout four synthetic periods, finally (at 140 min), resulting in a delay of one synthetic period behind the controls. The duration of these synthetic periods was variable and always longer than the controls." @default.
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• W2022302274 date "1970-05-01" @default.
• W2022302274 modified "2023-09-26" @default.
• W2022302274 title "Laser-induced changes in DNA synthesis and embryonic development in sea urchins" @default.
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• W2022302274 doi "https://doi.org/10.1016/0014-4827(70)90502-1" @default.
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