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• W2022306618 abstract "La revue de la littérature française et anglo-saxonne de ces 20 dernières années (1964–1984) a permis de colliger 975 réactions anaphylactoïdes de type immédiat, concernant les substances anesthésiologiques administrées par voie parentérale. Le mécanisme de l'accident n'est affirmé que dans la moitié des observations, et presque toujours a posteriori. Les tests immunoallergologiques les plus souvent utilisés pour le diagnostic sont les tests cutanés et les tests de Prausnitz-Küstner. Toutes les substances peuvent entraîner une anaphylaxie, mais il faut noter la plus grande responsabilité des myorelaxants (51 %) et des hypnotiques (42,3 %). La symptomatologie de l'accident est représentée par des signes cutanéomuqueux, cardiovasculaires, respiratoires et parfois digestifs. Les hypnotiques sont surtout responsables d'une symptomatologie cutanéomuqueuse, les myorelaxants de signes cardiovasculaires. Quant aux facteurs prédisposants, une allergie médicamenteuse est notée dans 37 % des cas, une atopie dans 38 %; la notion d'une ou plusieurs anesthésies antérieures est presque toujours retrouvée. A search of the French and English language literature of the last 20 years (1964–1984) yielded 975 cases of immediate anaphylactoid reactions due to anaesthetic drugs given parenterally. The accident mechanism was confirmed in only half the patients, and nearly always at a later date. The immunoallergological tests most often used in the diagnostic process were skin tests and Prausnitz-Küstner tests. Although all drugs could be responsible for an anaphylactic reaction, the greatest number of cases was due to muscle relaxants (51%) and hypnotic drugs (42.3%). The signs most often described were cutaneous, cardiovascular, respiratory and occasionally gastro-intestinal. Whilst hypnotic drugs were responsible for cutaneous signs, muscle relaxants gave cardiovascular signs. A past history of drug allergy was found in 37% of cases, and atopy in 38%; virtually all patients had already had one or more anaesthetics." @default.
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• W2022306618 date "1985-01-01" @default.
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• W2022306618 title "Réévaluation des risques respectifs d'anaphylaxie et d'histaminolibération avec les substances anesthésiologiques" @default.
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• W2022306618 doi "https://doi.org/10.1016/s0750-7658(85)80200-8" @default.
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