Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022307252> ?p ?o ?g. }
- W2022307252 endingPage "896" @default.
- W2022307252 startingPage "887" @default.
- W2022307252 abstract "Abstract In image analysis of two‐dimensional electrophoresis gels, individual spots need to be identified and quantified. Two classes of algorithms are commonly applied to this task. Parametric methods rely on a model, making strong assumptions about spot appearance, but are often insufficiently flexible to adequately represent all spots that may be present in a gel. Nonparametric methods make no assumptions about spot appearance and consequently impose few constraints on spot detection, allowing more flexibility but reducing robustness when image data is complex. We describe a parametric representation of spot shape that is both general enough to represent unusual spots, and specific enough to introduce constraints on the interpretation of complex images. Our method uses a model of shape based on the statistics of an annotated training set. The model allows new spot shapes, belonging to the same statistical distribution as the training set, to be generated. To represent spot appearance we use the statistically derived shape convolved with a Gaussian kernel, simulating the diffusion process in spot formation. We show that the statistical model of spot appearance and shape is able to fit to image data more closely than the commonly used spot parameterizations based solely on Gaussian and diffusion models. We show that improvements in model fitting are gained without degrading the specificity of the representation." @default.
- W2022307252 created "2016-06-24" @default.
- W2022307252 creator A5023967898 @default.
- W2022307252 creator A5026327215 @default.
- W2022307252 creator A5080105817 @default.
- W2022307252 date "2003-06-01" @default.
- W2022307252 modified "2023-10-16" @default.
- W2022307252 title "Statistical models of shape for the analysis of protein spots in two‐dimensional electrophoresis gel images" @default.
- W2022307252 cites W1492555913 @default.
- W2022307252 cites W151981251 @default.
- W2022307252 cites W1973550088 @default.
- W2022307252 cites W2012859298 @default.
- W2022307252 cites W2030462329 @default.
- W2022307252 cites W2032618685 @default.
- W2022307252 cites W2038753515 @default.
- W2022307252 cites W2038952578 @default.
- W2022307252 cites W2058871007 @default.
- W2022307252 cites W2084364180 @default.
- W2022307252 cites W2092253644 @default.
- W2022307252 cites W2099530880 @default.
- W2022307252 cites W2125767889 @default.
- W2022307252 cites W2125848778 @default.
- W2022307252 cites W2130771648 @default.
- W2022307252 cites W2132396702 @default.
- W2022307252 cites W2144242041 @default.
- W2022307252 cites W2148107745 @default.
- W2022307252 cites W2154543700 @default.
- W2022307252 cites W4234967189 @default.
- W2022307252 doi "https://doi.org/10.1002/pmic.200300421" @default.
- W2022307252 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12833512" @default.
- W2022307252 hasPublicationYear "2003" @default.
- W2022307252 type Work @default.
- W2022307252 sameAs 2022307252 @default.
- W2022307252 citedByCount "50" @default.
- W2022307252 countsByYear W20223072522012 @default.
- W2022307252 countsByYear W20223072522014 @default.
- W2022307252 countsByYear W20223072522015 @default.
- W2022307252 countsByYear W20223072522016 @default.
- W2022307252 countsByYear W20223072522017 @default.
- W2022307252 countsByYear W20223072522021 @default.
- W2022307252 crossrefType "journal-article" @default.
- W2022307252 hasAuthorship W2022307252A5023967898 @default.
- W2022307252 hasAuthorship W2022307252A5026327215 @default.
- W2022307252 hasAuthorship W2022307252A5080105817 @default.
- W2022307252 hasBestOaLocation W20223072521 @default.
- W2022307252 hasConcept C102366305 @default.
- W2022307252 hasConcept C104317684 @default.
- W2022307252 hasConcept C105795698 @default.
- W2022307252 hasConcept C114289077 @default.
- W2022307252 hasConcept C115961682 @default.
- W2022307252 hasConcept C117251300 @default.
- W2022307252 hasConcept C121332964 @default.
- W2022307252 hasConcept C147789679 @default.
- W2022307252 hasConcept C153180895 @default.
- W2022307252 hasConcept C154945302 @default.
- W2022307252 hasConcept C163716315 @default.
- W2022307252 hasConcept C17744445 @default.
- W2022307252 hasConcept C185592680 @default.
- W2022307252 hasConcept C199539241 @default.
- W2022307252 hasConcept C2776359362 @default.
- W2022307252 hasConcept C2781255879 @default.
- W2022307252 hasConcept C33923547 @default.
- W2022307252 hasConcept C41008148 @default.
- W2022307252 hasConcept C55493867 @default.
- W2022307252 hasConcept C61224824 @default.
- W2022307252 hasConcept C62520636 @default.
- W2022307252 hasConcept C63479239 @default.
- W2022307252 hasConcept C83248878 @default.
- W2022307252 hasConcept C94625758 @default.
- W2022307252 hasConceptScore W2022307252C102366305 @default.
- W2022307252 hasConceptScore W2022307252C104317684 @default.
- W2022307252 hasConceptScore W2022307252C105795698 @default.
- W2022307252 hasConceptScore W2022307252C114289077 @default.
- W2022307252 hasConceptScore W2022307252C115961682 @default.
- W2022307252 hasConceptScore W2022307252C117251300 @default.
- W2022307252 hasConceptScore W2022307252C121332964 @default.
- W2022307252 hasConceptScore W2022307252C147789679 @default.
- W2022307252 hasConceptScore W2022307252C153180895 @default.
- W2022307252 hasConceptScore W2022307252C154945302 @default.
- W2022307252 hasConceptScore W2022307252C163716315 @default.
- W2022307252 hasConceptScore W2022307252C17744445 @default.
- W2022307252 hasConceptScore W2022307252C185592680 @default.
- W2022307252 hasConceptScore W2022307252C199539241 @default.
- W2022307252 hasConceptScore W2022307252C2776359362 @default.
- W2022307252 hasConceptScore W2022307252C2781255879 @default.
- W2022307252 hasConceptScore W2022307252C33923547 @default.
- W2022307252 hasConceptScore W2022307252C41008148 @default.
- W2022307252 hasConceptScore W2022307252C55493867 @default.
- W2022307252 hasConceptScore W2022307252C61224824 @default.
- W2022307252 hasConceptScore W2022307252C62520636 @default.
- W2022307252 hasConceptScore W2022307252C63479239 @default.
- W2022307252 hasConceptScore W2022307252C83248878 @default.
- W2022307252 hasConceptScore W2022307252C94625758 @default.
- W2022307252 hasIssue "6" @default.
- W2022307252 hasLocation W20223072521 @default.
- W2022307252 hasLocation W20223072522 @default.
- W2022307252 hasOpenAccess W2022307252 @default.
- W2022307252 hasPrimaryLocation W20223072521 @default.