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• W2022332288 abstract "By using an expectation-maximization maximum likelihood estimation algorithm to improve the lateral resolution of a recently developed non-interferometric wide-field optical profilometer, we obtain super-resolution bright-field optical images of nanometer features on a flat surface. The optical profilometer employs a 365-nm light source and an ordinary objective lens of a 0.95 numerical aperture. For objects of 100 nm thickness, lateral features about lambda/7 can be resolved in the restored images without fluorescence labeling. Current image acquisition rate is 0.1 frame/sec, which is limited by the brightness of the light source. With a brighter light source, the imaging speed can be fast enough for real-time observation of dynamic activities in the nanometer scale." @default.
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• W2022332288 date "2004-11-01" @default.
• W2022332288 modified "2023-09-27" @default.
• W2022332288 title "Super-resolution bright-field optical microscopy based on nanometer topographic contrast" @default.
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• W2022332288 doi "https://doi.org/10.1002/jemt.20091" @default.
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