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• W2022333173 abstract "Interleukin-10 (IL-10) is known to be spontaneously produced by human peripheral blood mononuclear cells. In order to define the cell type in which IL-10 gene is spontaneously expressed we used the reverse polymerase chain reaction for IL-10 mRNA expression, which was also used to study the effects of cycloheximide (CHX). First, we found that IL-10 mRNA is spontaneously expressed in monocytes and B cells but not T cells from healthy donors, and second, we demonstrated that CHX superinduces IL-10 mRNA in monocytes and B cells. Experiments including nuclear run-on analyses established that the effects of CHX on IL-10 gene expression involve both gene transcription and mRNA stabilization." @default.
• W2022333173 created "2016-06-24" @default.
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• W2022333173 date "1995-03-01" @default.
• W2022333173 modified "2023-10-18" @default.
• W2022333173 title "Spontaneous and cycloheximide-induced interleukin-10 mRNA expression in human mononuclear cells" @default.
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• W2022333173 doi "https://doi.org/10.1016/0161-5890(94)00158-w" @default.
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