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- W2022335060 abstract "Introduction: Members of the TGF-beta superfamily are known for their heterogeneous effects on cancer progression. Activin, a growth factor in this superfamily, triggers the activation of Smad 3, which then translocates to the nucleus where it acts as a transcription factor for proteins involved in cell cycle control. Activin/Smad 3 signal transduction contributes to G1 cell cycle arrest in breast cancer T47D cells, and loss of nuclear Smad 3 has been associated with cellular dedifferentiation in breast cancer patient samples." @default.
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- W2022335060 date "2008-02-01" @default.
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- W2022335060 title "QS283. Effect of Activin ond Smad 3 Signal Transduction on Breast Cancer Cell Lines" @default.
- W2022335060 doi "https://doi.org/10.1016/j.jss.2007.12.534" @default.
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