Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022336568> ?p ?o ?g. }
- W2022336568 endingPage "6" @default.
- W2022336568 startingPage "1" @default.
- W2022336568 abstract "Peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptors that function as transcription factors regulating the expression of numerous target genes. PPARs play an essential role in various physiological and pathological processes, especially in energy metabolism. It has long been known that metabolism and circadian clocks are tightly intertwined. However, the mechanism of how they influence each other is not fully understood. Recently, all three PPAR isoforms were found to be rhythmically expressed in given mouse tissues. Among them, PPAR α and PPAR γ are direct regulators of core clock components, Bmal1 and Rev-erb α , and, conversely, PPAR α is also a direct Bmal1 target gene. More importantly, recent studies using knockout mice revealed that all PPARs exert given functions in a circadian manner. These findings demonstrated a novel role of PPARs as regulators in correlating circadian rhythm and metabolism. In this review, we summarize advances in our understanding of PPARs in circadian regulation." @default.
- W2022336568 created "2016-06-24" @default.
- W2022336568 creator A5033788719 @default.
- W2022336568 creator A5061568119 @default.
- W2022336568 date "2014-01-01" @default.
- W2022336568 modified "2023-10-17" @default.
- W2022336568 title "PPARs Integrate the Mammalian Clock and Energy Metabolism" @default.
- W2022336568 cites W1524910854 @default.
- W2022336568 cites W1575558149 @default.
- W2022336568 cites W1669074779 @default.
- W2022336568 cites W1968319041 @default.
- W2022336568 cites W1969084491 @default.
- W2022336568 cites W1972960019 @default.
- W2022336568 cites W1973129975 @default.
- W2022336568 cites W1975884121 @default.
- W2022336568 cites W1979963836 @default.
- W2022336568 cites W1993515784 @default.
- W2022336568 cites W1993901564 @default.
- W2022336568 cites W1995100342 @default.
- W2022336568 cites W2013099460 @default.
- W2022336568 cites W2017611869 @default.
- W2022336568 cites W2021808114 @default.
- W2022336568 cites W2024254257 @default.
- W2022336568 cites W2025018502 @default.
- W2022336568 cites W2026930722 @default.
- W2022336568 cites W2029664649 @default.
- W2022336568 cites W2038185360 @default.
- W2022336568 cites W2042646534 @default.
- W2022336568 cites W2043425632 @default.
- W2022336568 cites W2043577247 @default.
- W2022336568 cites W2046657713 @default.
- W2022336568 cites W2053210485 @default.
- W2022336568 cites W2054745481 @default.
- W2022336568 cites W2054851194 @default.
- W2022336568 cites W2055023418 @default.
- W2022336568 cites W2065472379 @default.
- W2022336568 cites W2068231503 @default.
- W2022336568 cites W2087133841 @default.
- W2022336568 cites W2088037887 @default.
- W2022336568 cites W2091288807 @default.
- W2022336568 cites W2097164746 @default.
- W2022336568 cites W2103049241 @default.
- W2022336568 cites W2103116278 @default.
- W2022336568 cites W2104712753 @default.
- W2022336568 cites W2115505876 @default.
- W2022336568 cites W2119981016 @default.
- W2022336568 cites W2120372697 @default.
- W2022336568 cites W2122503953 @default.
- W2022336568 cites W2123319274 @default.
- W2022336568 cites W2138162648 @default.
- W2022336568 cites W2139342290 @default.
- W2022336568 cites W2150660191 @default.
- W2022336568 cites W2152181679 @default.
- W2022336568 cites W2154114022 @default.
- W2022336568 cites W2157958154 @default.
- W2022336568 cites W2162423616 @default.
- W2022336568 cites W2163839619 @default.
- W2022336568 cites W2167008303 @default.
- W2022336568 cites W2168953650 @default.
- W2022336568 cites W2222722063 @default.
- W2022336568 cites W3026170990 @default.
- W2022336568 cites W4252969106 @default.
- W2022336568 doi "https://doi.org/10.1155/2014/653017" @default.
- W2022336568 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3945976" @default.
- W2022336568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24693278" @default.
- W2022336568 hasPublicationYear "2014" @default.
- W2022336568 type Work @default.
- W2022336568 sameAs 2022336568 @default.
- W2022336568 citedByCount "163" @default.
- W2022336568 countsByYear W20223365682014 @default.
- W2022336568 countsByYear W20223365682015 @default.
- W2022336568 countsByYear W20223365682016 @default.
- W2022336568 countsByYear W20223365682017 @default.
- W2022336568 countsByYear W20223365682018 @default.
- W2022336568 countsByYear W20223365682019 @default.
- W2022336568 countsByYear W20223365682020 @default.
- W2022336568 countsByYear W20223365682021 @default.
- W2022336568 countsByYear W20223365682022 @default.
- W2022336568 countsByYear W20223365682023 @default.
- W2022336568 crossrefType "journal-article" @default.
- W2022336568 hasAuthorship W2022336568A5033788719 @default.
- W2022336568 hasAuthorship W2022336568A5061568119 @default.
- W2022336568 hasBestOaLocation W20223365681 @default.
- W2022336568 hasConcept C104317684 @default.
- W2022336568 hasConcept C121446783 @default.
- W2022336568 hasConcept C134018914 @default.
- W2022336568 hasConcept C14036430 @default.
- W2022336568 hasConcept C169760540 @default.
- W2022336568 hasConcept C170493617 @default.
- W2022336568 hasConcept C182704531 @default.
- W2022336568 hasConcept C187345961 @default.
- W2022336568 hasConcept C2986317502 @default.
- W2022336568 hasConcept C38606739 @default.
- W2022336568 hasConcept C53345823 @default.
- W2022336568 hasConcept C54355233 @default.
- W2022336568 hasConcept C63932345 @default.
- W2022336568 hasConcept C86339819 @default.
- W2022336568 hasConcept C86803240 @default.