FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022343786> ?p ?o ?g. }

• W2022343786 endingPage "573" @default.
• W2022343786 startingPage "565" @default.
• W2022343786 abstract "The aim of this study was to investigate whether morphine can be transferred along the olfactory pathway to the CNS, thereby circumventing the blood-brain barrier, after nasal administration to rodents. Radiolabelled and unlabelled morphine were administered via the right nostril to mice and rats. Olfactory bulbs, brain tissue and blood samples were collected. Morphine-derived radioactivity was measured using liquid scintillation (LS) and the concentrations of morphine and its metabolite morphine-3-glucuronide (M3G) were also assessed with high-performance liquid chromatography. The location of morphine-derived radioactivity in the rat brain was visualised by autoradiography. Overall, the levels of morphine in the right olfactory bulbs (ROBs) significantly exceeded those in the left olfactory bulbs (LOBs) and brain tissue samples 15, 60 and 240 min after right-sided nasal administration. Fifteen minutes after intravenous administration, there were no significant differences between olfactory bulbs and the other brain areas. Five minutes after nasal administration, autoradiography revealed radioactivity surrounding the ROB and reaching one of the ventricles in the brain. After 60 min, radioactivity had reached the peripheral parts of the ROB. All the techniques used in this study demonstrate that morphine was transferred along the olfactory pathway to the CNS after nasal administration to rodents." @default.
• W2022343786 created "2016-06-24" @default.
• W2022343786 creator A5010938772 @default.
• W2022343786 creator A5033635570 @default.
• W2022343786 creator A5038152196 @default.
• W2022343786 creator A5038818371 @default.
• W2022343786 creator A5041224691 @default.
• W2022343786 creator A5048569965 @default.
• W2022343786 creator A5052201999 @default.
• W2022343786 date "2005-04-01" @default.
• W2022343786 modified "2023-10-03" @default.
• W2022343786 title "Transfer of morphine along the olfactory pathway to the central nervous system after nasal administration to rodents" @default.
• W2022343786 cites W1485916853 @default.
• W2022343786 cites W1546508310 @default.
• W2022343786 cites W1968427961 @default.
• W2022343786 cites W1987456361 @default.
• W2022343786 cites W1988847966 @default.
• W2022343786 cites W1995796610 @default.
• W2022343786 cites W2003087697 @default.
• W2022343786 cites W2018567774 @default.
• W2022343786 cites W2024286088 @default.
• W2022343786 cites W2031000084 @default.
• W2022343786 cites W2034156920 @default.
• W2022343786 cites W2051273091 @default.
• W2022343786 cites W2051911305 @default.
• W2022343786 cites W2063626452 @default.
• W2022343786 cites W2069338103 @default.
• W2022343786 cites W2072417219 @default.
• W2022343786 cites W2077756131 @default.
• W2022343786 cites W2083588057 @default.
• W2022343786 cites W2087890691 @default.
• W2022343786 cites W2089978730 @default.
• W2022343786 cites W2092877978 @default.
• W2022343786 cites W2100300954 @default.
• W2022343786 cites W2122901772 @default.
• W2022343786 cites W2140257707 @default.
• W2022343786 cites W2149687476 @default.
• W2022343786 cites W2157021772 @default.
• W2022343786 cites W4235446269 @default.
• W2022343786 doi "https://doi.org/10.1016/j.ejps.2005.01.009" @default.
• W2022343786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15784346" @default.
• W2022343786 hasPublicationYear "2005" @default.
• W2022343786 type Work @default.
• W2022343786 sameAs 2022343786 @default.
• W2022343786 citedByCount "83" @default.
• W2022343786 countsByYear W20223437862012 @default.
• W2022343786 countsByYear W20223437862013 @default.
• W2022343786 countsByYear W20223437862014 @default.
• W2022343786 countsByYear W20223437862015 @default.
• W2022343786 countsByYear W20223437862016 @default.
• W2022343786 countsByYear W20223437862017 @default.
• W2022343786 countsByYear W20223437862018 @default.
• W2022343786 countsByYear W20223437862019 @default.
• W2022343786 countsByYear W20223437862020 @default.
• W2022343786 countsByYear W20223437862021 @default.
• W2022343786 countsByYear W20223437862022 @default.
• W2022343786 countsByYear W20223437862023 @default.
• W2022343786 crossrefType "journal-article" @default.
• W2022343786 hasAuthorship W2022343786A5010938772 @default.
• W2022343786 hasAuthorship W2022343786A5033635570 @default.
• W2022343786 hasAuthorship W2022343786A5038152196 @default.
• W2022343786 hasAuthorship W2022343786A5038818371 @default.
• W2022343786 hasAuthorship W2022343786A5041224691 @default.
• W2022343786 hasAuthorship W2022343786A5048569965 @default.
• W2022343786 hasAuthorship W2022343786A5052201999 @default.
• W2022343786 hasConcept C105702510 @default.
• W2022343786 hasConcept C118552586 @default.
• W2022343786 hasConcept C126322002 @default.
• W2022343786 hasConcept C185592680 @default.
• W2022343786 hasConcept C201792869 @default.
• W2022343786 hasConcept C2777389121 @default.
• W2022343786 hasConcept C2777477808 @default.
• W2022343786 hasConcept C2778311950 @default.
• W2022343786 hasConcept C2779789940 @default.
• W2022343786 hasConcept C2781377823 @default.
• W2022343786 hasConcept C42219234 @default.
• W2022343786 hasConcept C529278444 @default.
• W2022343786 hasConcept C71924100 @default.
• W2022343786 hasConcept C85663871 @default.
• W2022343786 hasConcept C98274493 @default.
• W2022343786 hasConceptScore W2022343786C105702510 @default.
• W2022343786 hasConceptScore W2022343786C118552586 @default.
• W2022343786 hasConceptScore W2022343786C126322002 @default.
• W2022343786 hasConceptScore W2022343786C185592680 @default.
• W2022343786 hasConceptScore W2022343786C201792869 @default.
• W2022343786 hasConceptScore W2022343786C2777389121 @default.
• W2022343786 hasConceptScore W2022343786C2777477808 @default.
• W2022343786 hasConceptScore W2022343786C2778311950 @default.
• W2022343786 hasConceptScore W2022343786C2779789940 @default.
• W2022343786 hasConceptScore W2022343786C2781377823 @default.
• W2022343786 hasConceptScore W2022343786C42219234 @default.
• W2022343786 hasConceptScore W2022343786C529278444 @default.
• W2022343786 hasConceptScore W2022343786C71924100 @default.
• W2022343786 hasConceptScore W2022343786C85663871 @default.
• W2022343786 hasConceptScore W2022343786C98274493 @default.
• W2022343786 hasIssue "5" @default.
• W2022343786 hasLocation W20223437861 @default.
• W2022343786 hasLocation W20223437862 @default.

• next