Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022352586> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2022352586 endingPage "2290" @default.
- W2022352586 startingPage "2285" @default.
- W2022352586 abstract "The authors have studied five cases of biopsy-proven pulmonary toxicity caused by the administration of mitomycin C (M), vincristine, and cisplatin in 64 patients with advanced non-small cell lung cancer. The clinical triad of progressive dyspnea, rales, and pulmonary infiltrates presented in all five cases. In addition, pulmonary function tests showed hypoxemia (four/five), reduced forced vital capacity (three/four), total lung capacity (two/three), and forced expiratory volume (FEV1) (three/four) and very profound reduction in diffusion capacity (three/three). Transbronchial biopsy for tissue examination was necessary to rule out other causes. Characteristics but nonspecific pathologic changes were documented in all five cases. All the patients responded quickly and dramatically to high-dose glucocorticoids with improvement of hypoxia, dyspnea, exercise tolerance, and sense of well being. In three patients the pulmonary infiltrates cleared. However, abrupt stopping or early withdrawal of steroid resulted in aggravation of dyspnea and pulmonary infiltrate in three cases who improved subsequently with escalation of steroid doses. The authors conclude that the treatment of choice for pulmonary toxicity induced by M or M-containing chemotherapy regimens is a high dose of glucocorticoid and discontinuation of M at once when suspicion is raised. Cancer 57:2285–2290, 1986." @default.
- W2022352586 created "2016-06-24" @default.
- W2022352586 creator A5036613219 @default.
- W2022352586 creator A5058569055 @default.
- W2022352586 creator A5064005622 @default.
- W2022352586 creator A5070509518 @default.
- W2022352586 creator A5074990264 @default.
- W2022352586 creator A5077630952 @default.
- W2022352586 date "1986-06-15" @default.
- W2022352586 modified "2023-10-18" @default.
- W2022352586 title "Pulmonary toxicity induced by mitomycin C is highly responsive to glucocorticoids" @default.
- W2022352586 cites W1964624837 @default.
- W2022352586 cites W1972728216 @default.
- W2022352586 cites W1985359290 @default.
- W2022352586 cites W2002893101 @default.
- W2022352586 cites W2006959398 @default.
- W2022352586 cites W2014322712 @default.
- W2022352586 cites W2017985111 @default.
- W2022352586 cites W2038144748 @default.
- W2022352586 cites W2047367549 @default.
- W2022352586 cites W2048531401 @default.
- W2022352586 cites W2065961310 @default.
- W2022352586 cites W2075788990 @default.
- W2022352586 cites W2076668534 @default.
- W2022352586 cites W2100577791 @default.
- W2022352586 cites W4299161135 @default.
- W2022352586 doi "https://doi.org/10.1002/1097-0142(19860615)57:12<2285::aid-cncr2820571209>3.0.co;2-4" @default.
- W2022352586 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3084059" @default.
- W2022352586 hasPublicationYear "1986" @default.
- W2022352586 type Work @default.
- W2022352586 sameAs 2022352586 @default.
- W2022352586 citedByCount "44" @default.
- W2022352586 countsByYear W20223525862013 @default.
- W2022352586 countsByYear W20223525862014 @default.
- W2022352586 countsByYear W20223525862018 @default.
- W2022352586 crossrefType "journal-article" @default.
- W2022352586 hasAuthorship W2022352586A5036613219 @default.
- W2022352586 hasAuthorship W2022352586A5058569055 @default.
- W2022352586 hasAuthorship W2022352586A5064005622 @default.
- W2022352586 hasAuthorship W2022352586A5070509518 @default.
- W2022352586 hasAuthorship W2022352586A5074990264 @default.
- W2022352586 hasAuthorship W2022352586A5077630952 @default.
- W2022352586 hasConcept C126322002 @default.
- W2022352586 hasConcept C141071460 @default.
- W2022352586 hasConcept C2776178081 @default.
- W2022352586 hasConcept C2776256026 @default.
- W2022352586 hasConcept C2776694085 @default.
- W2022352586 hasConcept C2776779939 @default.
- W2022352586 hasConcept C2777714996 @default.
- W2022352586 hasConcept C2778715236 @default.
- W2022352586 hasConcept C2779338040 @default.
- W2022352586 hasConcept C2781047374 @default.
- W2022352586 hasConcept C29730261 @default.
- W2022352586 hasConcept C42219234 @default.
- W2022352586 hasConcept C71924100 @default.
- W2022352586 hasConcept C75603125 @default.
- W2022352586 hasConcept C90924648 @default.
- W2022352586 hasConceptScore W2022352586C126322002 @default.
- W2022352586 hasConceptScore W2022352586C141071460 @default.
- W2022352586 hasConceptScore W2022352586C2776178081 @default.
- W2022352586 hasConceptScore W2022352586C2776256026 @default.
- W2022352586 hasConceptScore W2022352586C2776694085 @default.
- W2022352586 hasConceptScore W2022352586C2776779939 @default.
- W2022352586 hasConceptScore W2022352586C2777714996 @default.
- W2022352586 hasConceptScore W2022352586C2778715236 @default.
- W2022352586 hasConceptScore W2022352586C2779338040 @default.
- W2022352586 hasConceptScore W2022352586C2781047374 @default.
- W2022352586 hasConceptScore W2022352586C29730261 @default.
- W2022352586 hasConceptScore W2022352586C42219234 @default.
- W2022352586 hasConceptScore W2022352586C71924100 @default.
- W2022352586 hasConceptScore W2022352586C75603125 @default.
- W2022352586 hasConceptScore W2022352586C90924648 @default.
- W2022352586 hasIssue "12" @default.
- W2022352586 hasLocation W20223525861 @default.
- W2022352586 hasLocation W20223525862 @default.
- W2022352586 hasOpenAccess W2022352586 @default.
- W2022352586 hasPrimaryLocation W20223525861 @default.
- W2022352586 hasRelatedWork W1967103478 @default.
- W2022352586 hasRelatedWork W2042573872 @default.
- W2022352586 hasRelatedWork W2081430017 @default.
- W2022352586 hasRelatedWork W2091724184 @default.
- W2022352586 hasRelatedWork W2170354584 @default.
- W2022352586 hasRelatedWork W2239800571 @default.
- W2022352586 hasRelatedWork W2344373170 @default.
- W2022352586 hasRelatedWork W2396857433 @default.
- W2022352586 hasRelatedWork W2410608929 @default.
- W2022352586 hasRelatedWork W85838552 @default.
- W2022352586 hasVolume "57" @default.
- W2022352586 isParatext "false" @default.
- W2022352586 isRetracted "false" @default.
- W2022352586 magId "2022352586" @default.
- W2022352586 workType "article" @default.