Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022352598> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2022352598 endingPage "446" @default.
- W2022352598 startingPage "441" @default.
- W2022352598 abstract "Immunization of mice with 2,4-dinitrophenyl-Bordetella pertussis (DNP-BP) failed to induce anti-DNP IgE responses. Administration of DNP-BP induced, however, the formation of anti-DNP IgE B memory cells, as demonstrated by adoptive transfer. Furthermore, mice pretreated with DNP-BP and primed with 2 micrograms DNP-ovalbumin (OA) in alum 2 weeks later produced high day-7 anti-DNP IgE levels. These subsided to near undetectable levels by day 12-14. The transient expression of serum IgE levels was accompanied by normal levels of anti-DNP IgG. The anti-OA response induced as a result of priming with DNP-OA in alum was not affected by pretreatment with DNP-BP. IgG subclass analysis revealed that mice pretreated with DNP-BP had elevated levels of IgG2a and reduced levels of IgG1 as compared to control (TNP-keyhole limpet hemocyanin-pretreated) mice. Treatment of mice with an anti-interferon-gamma monoclonal antibody, shortly after immunization with DNP-BP, not only reduced anti-DNP IgG2a levels, but prevented the sharp anti-DNP IgE decline that occurred after priming with DNP-OA in alum. These results suggest that DNP-BP-induced interferon-gamma production modulates Ig isotype expression in vivo in an anti-gen-specific manner." @default.
- W2022352598 created "2016-06-24" @default.
- W2022352598 creator A5011921521 @default.
- W2022352598 creator A5047571769 @default.
- W2022352598 creator A5080209695 @default.
- W2022352598 date "1989-03-01" @default.
- W2022352598 modified "2023-10-14" @default.
- W2022352598 title "Role of interferon-gamma in the modulation of the IgE response by 2,4-dinitrophenyl-Bordetella pertussis vaccine in the mouse" @default.
- W2022352598 cites W1512059978 @default.
- W2022352598 cites W1975029709 @default.
- W2022352598 cites W1984915036 @default.
- W2022352598 cites W1990252611 @default.
- W2022352598 cites W2005246059 @default.
- W2022352598 cites W2012428595 @default.
- W2022352598 cites W2041753098 @default.
- W2022352598 cites W2073023385 @default.
- W2022352598 cites W2083185383 @default.
- W2022352598 cites W2110288713 @default.
- W2022352598 cites W2171009645 @default.
- W2022352598 doi "https://doi.org/10.1002/eji.1830190305" @default.
- W2022352598 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2495968" @default.
- W2022352598 hasPublicationYear "1989" @default.
- W2022352598 type Work @default.
- W2022352598 sameAs 2022352598 @default.
- W2022352598 citedByCount "9" @default.
- W2022352598 crossrefType "journal-article" @default.
- W2022352598 hasAuthorship W2022352598A5011921521 @default.
- W2022352598 hasAuthorship W2022352598A5047571769 @default.
- W2022352598 hasAuthorship W2022352598A5080209695 @default.
- W2022352598 hasConcept C100701293 @default.
- W2022352598 hasConcept C141105273 @default.
- W2022352598 hasConcept C153911025 @default.
- W2022352598 hasConcept C159654299 @default.
- W2022352598 hasConcept C178790620 @default.
- W2022352598 hasConcept C185592680 @default.
- W2022352598 hasConcept C203014093 @default.
- W2022352598 hasConcept C2776090121 @default.
- W2022352598 hasConcept C2776946954 @default.
- W2022352598 hasConcept C2777582894 @default.
- W2022352598 hasConcept C2777991845 @default.
- W2022352598 hasConcept C2778177356 @default.
- W2022352598 hasConcept C2779915011 @default.
- W2022352598 hasConcept C2780924562 @default.
- W2022352598 hasConcept C523546767 @default.
- W2022352598 hasConcept C542903549 @default.
- W2022352598 hasConcept C54355233 @default.
- W2022352598 hasConcept C59822182 @default.
- W2022352598 hasConcept C81444415 @default.
- W2022352598 hasConcept C86803240 @default.
- W2022352598 hasConcept C8891405 @default.
- W2022352598 hasConcept C90375314 @default.
- W2022352598 hasConceptScore W2022352598C100701293 @default.
- W2022352598 hasConceptScore W2022352598C141105273 @default.
- W2022352598 hasConceptScore W2022352598C153911025 @default.
- W2022352598 hasConceptScore W2022352598C159654299 @default.
- W2022352598 hasConceptScore W2022352598C178790620 @default.
- W2022352598 hasConceptScore W2022352598C185592680 @default.
- W2022352598 hasConceptScore W2022352598C203014093 @default.
- W2022352598 hasConceptScore W2022352598C2776090121 @default.
- W2022352598 hasConceptScore W2022352598C2776946954 @default.
- W2022352598 hasConceptScore W2022352598C2777582894 @default.
- W2022352598 hasConceptScore W2022352598C2777991845 @default.
- W2022352598 hasConceptScore W2022352598C2778177356 @default.
- W2022352598 hasConceptScore W2022352598C2779915011 @default.
- W2022352598 hasConceptScore W2022352598C2780924562 @default.
- W2022352598 hasConceptScore W2022352598C523546767 @default.
- W2022352598 hasConceptScore W2022352598C542903549 @default.
- W2022352598 hasConceptScore W2022352598C54355233 @default.
- W2022352598 hasConceptScore W2022352598C59822182 @default.
- W2022352598 hasConceptScore W2022352598C81444415 @default.
- W2022352598 hasConceptScore W2022352598C86803240 @default.
- W2022352598 hasConceptScore W2022352598C8891405 @default.
- W2022352598 hasConceptScore W2022352598C90375314 @default.
- W2022352598 hasIssue "3" @default.
- W2022352598 hasLocation W20223525981 @default.
- W2022352598 hasLocation W20223525982 @default.
- W2022352598 hasOpenAccess W2022352598 @default.
- W2022352598 hasPrimaryLocation W20223525981 @default.
- W2022352598 hasRelatedWork W10685203 @default.
- W2022352598 hasRelatedWork W1518978716 @default.
- W2022352598 hasRelatedWork W1823656271 @default.
- W2022352598 hasRelatedWork W2016283383 @default.
- W2022352598 hasRelatedWork W2022352598 @default.
- W2022352598 hasRelatedWork W2027916689 @default.
- W2022352598 hasRelatedWork W2396547575 @default.
- W2022352598 hasRelatedWork W4321746747 @default.
- W2022352598 hasRelatedWork W4322086318 @default.
- W2022352598 hasRelatedWork W1891812318 @default.
- W2022352598 hasVolume "19" @default.
- W2022352598 isParatext "false" @default.
- W2022352598 isRetracted "false" @default.
- W2022352598 magId "2022352598" @default.
- W2022352598 workType "article" @default.