FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022353607> ?p ?o ?g. }

• W2022353607 endingPage "47" @default.
• W2022353607 startingPage "39" @default.
• W2022353607 abstract "Organ culture of isolated arteries results in increased levels of endothelin ET(B) (ET(B)) receptor mRNA and in enhanced ET(B) receptor mediated contraction. The present study was designed to pinpoint the mitogen-activated protein kinase (MAPK) subtype involved in up-regulation of ET(B) receptors after organ culture of rat mesenteric arteries. Western blot and selective antibodies towards constitutional and phosphorylated MAPKs revealed the appearance of phosphorylated MAPK of the extracellular signal-regulated kinases (ERK) 1/2 type at 3 h of organ culture. The functional ET(B) receptor and its mRNA expression were up-regulated after 24 h of organ culture. Following incubation with the MEK 1/2 specific inhibitor SB408039 or the raf inhibitor SB386023b the up-regulation was attenuated both for ET(B) receptor responses and in ET(B) receptor mRNA expression in the vessel segments. Neither Western blot nor myograph or mRNA analysis showed involvement of the other MAPKs studied. Our results suggest that the ERK1/2 MAPKs are involved in the endothelin ET(B) receptor up-regulation following organ culture." @default.
• W2022353607 created "2016-06-24" @default.
• W2022353607 creator A5000442895 @default.
• W2022353607 creator A5028480560 @default.
• W2022353607 creator A5077542341 @default.
• W2022353607 creator A5084413123 @default.
• W2022353607 date "2003-12-01" @default.
• W2022353607 modified "2023-10-14" @default.
• W2022353607 title "Role of mitogen-activated protein kinases in endothelin ETB receptor up-regulation after organ culture of rat mesenteric artery" @default.
• W2022353607 cites W1566737177 @default.
• W2022353607 cites W1967591341 @default.
• W2022353607 cites W1972817054 @default.
• W2022353607 cites W1974073030 @default.
• W2022353607 cites W1976244781 @default.
• W2022353607 cites W1979813283 @default.
• W2022353607 cites W1983289760 @default.
• W2022353607 cites W1984715375 @default.
• W2022353607 cites W1997180589 @default.
• W2022353607 cites W2001470147 @default.
• W2022353607 cites W2008458085 @default.
• W2022353607 cites W2013089078 @default.
• W2022353607 cites W2018380860 @default.
• W2022353607 cites W2018946126 @default.
• W2022353607 cites W2029796239 @default.
• W2022353607 cites W2035936653 @default.
• W2022353607 cites W2053699291 @default.
• W2022353607 cites W2064509104 @default.
• W2022353607 cites W2078592006 @default.
• W2022353607 cites W2086262311 @default.
• W2022353607 cites W2109283410 @default.
• W2022353607 cites W2114791524 @default.
• W2022353607 cites W2123481720 @default.
• W2022353607 cites W2146155590 @default.
• W2022353607 cites W2168438265 @default.
• W2022353607 cites W2792659630 @default.
• W2022353607 doi "https://doi.org/10.1016/j.ejphar.2003.09.055" @default.
• W2022353607 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14660003" @default.
• W2022353607 hasPublicationYear "2003" @default.
• W2022353607 type Work @default.
• W2022353607 sameAs 2022353607 @default.
• W2022353607 citedByCount "35" @default.
• W2022353607 countsByYear W20223536072012 @default.
• W2022353607 countsByYear W20223536072013 @default.
• W2022353607 countsByYear W20223536072014 @default.
• W2022353607 countsByYear W20223536072015 @default.
• W2022353607 countsByYear W20223536072018 @default.
• W2022353607 crossrefType "journal-article" @default.
• W2022353607 hasAuthorship W2022353607A5000442895 @default.
• W2022353607 hasAuthorship W2022353607A5028480560 @default.
• W2022353607 hasAuthorship W2022353607A5077542341 @default.
• W2022353607 hasAuthorship W2022353607A5084413123 @default.
• W2022353607 hasConcept C104317684 @default.
• W2022353607 hasConcept C126322002 @default.
• W2022353607 hasConcept C132149769 @default.
• W2022353607 hasConcept C134018914 @default.
• W2022353607 hasConcept C144980905 @default.
• W2022353607 hasConcept C149601957 @default.
• W2022353607 hasConcept C153911025 @default.
• W2022353607 hasConcept C163415756 @default.
• W2022353607 hasConcept C170493617 @default.
• W2022353607 hasConcept C184235292 @default.
• W2022353607 hasConcept C202751555 @default.
• W2022353607 hasConcept C2776415932 @default.
• W2022353607 hasConcept C2779941686 @default.
• W2022353607 hasConcept C28483552 @default.
• W2022353607 hasConcept C55493867 @default.
• W2022353607 hasConcept C57074206 @default.
• W2022353607 hasConcept C71924100 @default.
• W2022353607 hasConcept C86803240 @default.
• W2022353607 hasConcept C95444343 @default.
• W2022353607 hasConceptScore W2022353607C104317684 @default.
• W2022353607 hasConceptScore W2022353607C126322002 @default.
• W2022353607 hasConceptScore W2022353607C132149769 @default.
• W2022353607 hasConceptScore W2022353607C134018914 @default.
• W2022353607 hasConceptScore W2022353607C144980905 @default.
• W2022353607 hasConceptScore W2022353607C149601957 @default.
• W2022353607 hasConceptScore W2022353607C153911025 @default.
• W2022353607 hasConceptScore W2022353607C163415756 @default.
• W2022353607 hasConceptScore W2022353607C170493617 @default.
• W2022353607 hasConceptScore W2022353607C184235292 @default.
• W2022353607 hasConceptScore W2022353607C202751555 @default.
• W2022353607 hasConceptScore W2022353607C2776415932 @default.
• W2022353607 hasConceptScore W2022353607C2779941686 @default.
• W2022353607 hasConceptScore W2022353607C28483552 @default.
• W2022353607 hasConceptScore W2022353607C55493867 @default.
• W2022353607 hasConceptScore W2022353607C57074206 @default.
• W2022353607 hasConceptScore W2022353607C71924100 @default.
• W2022353607 hasConceptScore W2022353607C86803240 @default.
• W2022353607 hasConceptScore W2022353607C95444343 @default.
• W2022353607 hasIssue "1-3" @default.
• W2022353607 hasLocation W20223536071 @default.
• W2022353607 hasLocation W20223536072 @default.
• W2022353607 hasOpenAccess W2022353607 @default.
• W2022353607 hasPrimaryLocation W20223536071 @default.
• W2022353607 hasRelatedWork W159479947 @default.
• W2022353607 hasRelatedWork W1968790869 @default.
• W2022353607 hasRelatedWork W1992367101 @default.
• W2022353607 hasRelatedWork W2002462594 @default.

• next