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- W2022353643 abstract "Several studies demonstrated that chromosome anchoring to nuclear structures is involved in the organization of the interphase nucleus. The Rabl configuration, a well-studied chromosome organization in the interphase nucleus, has been deeply studied in organisms with monocentric chromosomes but just slightly touched in species with holocentric chromosomes. In the present paper, by means of the isolation and chromosomal mapping of the C₀t DNA fraction and chromatin immunoprecipitation with anti-LEM-2 antibodies, we evidenced the presence of few foci where telomeres and subtelomeric regions cluster in the aphid interphase nuclei, suggesting the occurrence of a Rabl-like chromosome configuration. The same experimental approaches also evidenced that most of the repetitive DNA of the 2 X chromosomes is located at the periphery of the nucleus, whereas the ribosomal genes, located at 1 telomere of each X chromosome, are present towards the inner portion of the nucleus, favoring their transcriptional activity." @default.
- W2022353643 created "2016-06-24" @default.
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- W2022353643 date "2014-01-01" @default.
- W2022353643 modified "2023-09-25" @default.
- W2022353643 title "Occurrence of Rabl-Like Telomere Clustering in the Holocentric Chromosomes of the Peach Potato Aphid <b><i>Myzus persicae</i></b> (Hemiptera; Aphididae)" @default.
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- W2022353643 doi "https://doi.org/10.1159/000366049" @default.
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