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- W2022358488 abstract "The synthesis of 5- and 3-(1′-hydroxyalkyl)-substituted 5H-furan-2-ones 4a–d and 8a–d as well as 5-alkylidene-5H-furan-2-ones 5a–d is described. A study of the structure–activity relationship of these furanone-based natural product analogues towards two different quorum sensing systems is reported. Although the synthesized compounds are not as potent quorum sensing inhibitors as some natural counterparts and a synthetic analogue hereof, interesting structure–activity relationships are seen." @default.
- W2022358488 created "2016-06-24" @default.
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- W2022358488 date "2003-07-01" @default.
- W2022358488 modified "2023-10-17" @default.
- W2022358488 title "Synthesis of furanone-Based natural product analogues with quorum sensing antagonist activity" @default.
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- W2022358488 doi "https://doi.org/10.1016/s0968-0896(03)00295-5" @default.
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