FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022359639> ?p ?o ?g. }

• W2022359639 endingPage "409" @default.
• W2022359639 startingPage "404" @default.
• W2022359639 abstract "The critical discovery in the past two decades of the transient receptor potential (TRP) superfamily of ion channels has revealed the potential mechanisms by which cells sense diverse stimuli beyond the prototypical “five senses,” identifying ion channels that are gated by heat, cold, mechanical loading, osmolarity, and other physical and chemical stimuli. TRP vanilloid 4 (TRPV4) is a Ca 2+ ‐permeable nonselective cation channel that appears to play a mechanosensory or osmosensory role in several musculoskeletal tissues. In articular cartilage, TRPV4 exhibits osmotic sensitivity, controlling cellular volume recovery, and other physiologic responses to osmotic stress. TRPV4 is expressed in both osteoblasts and osteoclasts, and the absence of TRPV4 prevents disuse‐induced bone loss. TRPV4 activation promotes chondrogenesis by inducing SOX9 transcription, whereas a TRPV4 gain‐of‐function mutation leads to a developmental skeletal dysplasia, suggesting a critical role for TRPV4 in skeletal development. These studies provide mounting evidence for a regulatory role for the sensory channel TRPV4 in control of musculoskeletal tissues." @default.
• W2022359639 created "2016-06-24" @default.
• W2022359639 creator A5024300976 @default.
• W2022359639 creator A5069892540 @default.
• W2022359639 creator A5090627153 @default.
• W2022359639 date "2010-04-01" @default.
• W2022359639 modified "2023-10-18" @default.
• W2022359639 title "Transient receptor potential vanilloid 4" @default.
• W2022359639 cites W1511198581 @default.
• W2022359639 cites W1545384325 @default.
• W2022359639 cites W1707717597 @default.
• W2022359639 cites W1967031104 @default.
• W2022359639 cites W1973036355 @default.
• W2022359639 cites W1981787196 @default.
• W2022359639 cites W1988919269 @default.
• W2022359639 cites W1992024578 @default.
• W2022359639 cites W1997277355 @default.
• W2022359639 cites W1998106094 @default.
• W2022359639 cites W2000272921 @default.
• W2022359639 cites W2001479869 @default.
• W2022359639 cites W2011557706 @default.
• W2022359639 cites W2023966975 @default.
• W2022359639 cites W2029766879 @default.
• W2022359639 cites W2037800200 @default.
• W2022359639 cites W2038407070 @default.
• W2022359639 cites W2040501484 @default.
• W2022359639 cites W2044474278 @default.
• W2022359639 cites W2047301497 @default.
• W2022359639 cites W2049247347 @default.
• W2022359639 cites W2054388804 @default.
• W2022359639 cites W2060667756 @default.
• W2022359639 cites W2062367006 @default.
• W2022359639 cites W2074087706 @default.
• W2022359639 cites W2082525414 @default.
• W2022359639 cites W2104721296 @default.
• W2022359639 cites W2105523906 @default.
• W2022359639 cites W2107057154 @default.
• W2022359639 cites W2108704056 @default.
• W2022359639 cites W2113557381 @default.
• W2022359639 cites W2115967760 @default.
• W2022359639 cites W2118622904 @default.
• W2022359639 cites W2128576216 @default.
• W2022359639 cites W2128842689 @default.
• W2022359639 cites W2140496883 @default.
• W2022359639 cites W2142259793 @default.
• W2022359639 cites W2150070295 @default.
• W2022359639 doi "https://doi.org/10.1111/j.1749-6632.2010.05389.x" @default.
• W2022359639 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3580043" @default.
• W2022359639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20392266" @default.
• W2022359639 hasPublicationYear "2010" @default.
• W2022359639 type Work @default.
• W2022359639 sameAs 2022359639 @default.
• W2022359639 citedByCount "102" @default.
• W2022359639 countsByYear W20223596392012 @default.
• W2022359639 countsByYear W20223596392013 @default.
• W2022359639 countsByYear W20223596392014 @default.
• W2022359639 countsByYear W20223596392015 @default.
• W2022359639 countsByYear W20223596392016 @default.
• W2022359639 countsByYear W20223596392017 @default.
• W2022359639 countsByYear W20223596392018 @default.
• W2022359639 countsByYear W20223596392019 @default.
• W2022359639 countsByYear W20223596392020 @default.
• W2022359639 countsByYear W20223596392021 @default.
• W2022359639 countsByYear W20223596392022 @default.
• W2022359639 countsByYear W20223596392023 @default.
• W2022359639 crossrefType "journal-article" @default.
• W2022359639 hasAuthorship W2022359639A5024300976 @default.
• W2022359639 hasAuthorship W2022359639A5069892540 @default.
• W2022359639 hasAuthorship W2022359639A5090627153 @default.
• W2022359639 hasBestOaLocation W20223596392 @default.
• W2022359639 hasConcept C12554922 @default.
• W2022359639 hasConcept C129900496 @default.
• W2022359639 hasConcept C155164980 @default.
• W2022359639 hasConcept C160145004 @default.
• W2022359639 hasConcept C170493617 @default.
• W2022359639 hasConcept C185592680 @default.
• W2022359639 hasConcept C4001165 @default.
• W2022359639 hasConcept C50254741 @default.
• W2022359639 hasConcept C55493867 @default.
• W2022359639 hasConcept C86803240 @default.
• W2022359639 hasConcept C87649029 @default.
• W2022359639 hasConcept C90420996 @default.
• W2022359639 hasConcept C95444343 @default.
• W2022359639 hasConceptScore W2022359639C12554922 @default.
• W2022359639 hasConceptScore W2022359639C129900496 @default.
• W2022359639 hasConceptScore W2022359639C155164980 @default.
• W2022359639 hasConceptScore W2022359639C160145004 @default.
• W2022359639 hasConceptScore W2022359639C170493617 @default.
• W2022359639 hasConceptScore W2022359639C185592680 @default.
• W2022359639 hasConceptScore W2022359639C4001165 @default.
• W2022359639 hasConceptScore W2022359639C50254741 @default.
• W2022359639 hasConceptScore W2022359639C55493867 @default.
• W2022359639 hasConceptScore W2022359639C86803240 @default.
• W2022359639 hasConceptScore W2022359639C87649029 @default.
• W2022359639 hasConceptScore W2022359639C90420996 @default.
• W2022359639 hasConceptScore W2022359639C95444343 @default.
• W2022359639 hasIssue "1" @default.
• W2022359639 hasLocation W20223596391 @default.

• next