Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022363300> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2022363300 endingPage "47" @default.
- W2022363300 startingPage "45" @default.
- W2022363300 abstract "The binding of 16-phenoxy derivatives of prostaglandin (PG) F2 alpha to rat luteal membranes, and also their abortifacient potency in pregnant rats, have been studied. Competitive binding studies with various PG-analogues were performed in ovaries of juvenile rats pretreated with PMSG and HCG, and in parallel studies the abortifacient potency of these substances was tested in pregnant rats. It was observed that this class of derivatives bound to the PGF2 alpha receptor as well as, or even better than the parent compound PGF2 alpha. Modifications in the carboxyl group at C-1 yielded derivatives with a higher affinity for the receptor, in decreasing order of effectiveness as follows: -COOR greater than COOH greater than OH. The data obtained from the binding studies also compared well with data on the abortifacient potency in pregnant rats. It is concluded that the addition of a phenoxy group to either the lower or upper side chain of PGF2 alpha may augment the binding to the receptor as well as the biological responses induced by the post receptor effect." @default.
- W2022363300 created "2016-06-24" @default.
- W2022363300 creator A5078094010 @default.
- W2022363300 date "1988-01-01" @default.
- W2022363300 modified "2023-09-26" @default.
- W2022363300 title "Luteolytic potency of 16-phenoxy-derivatives of prostaglandin F2α" @default.
- W2022363300 cites W1775749144 @default.
- W2022363300 cites W1964296544 @default.
- W2022363300 cites W1986575509 @default.
- W2022363300 cites W2003371990 @default.
- W2022363300 cites W2032791398 @default.
- W2022363300 cites W2059741030 @default.
- W2022363300 cites W2060165698 @default.
- W2022363300 cites W2095126945 @default.
- W2022363300 cites W2304638861 @default.
- W2022363300 cites W2417398479 @default.
- W2022363300 doi "https://doi.org/10.1007/bf01960240" @default.
- W2022363300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3162421" @default.
- W2022363300 hasPublicationYear "1988" @default.
- W2022363300 type Work @default.
- W2022363300 sameAs 2022363300 @default.
- W2022363300 citedByCount "7" @default.
- W2022363300 countsByYear W20223633002015 @default.
- W2022363300 countsByYear W20223633002016 @default.
- W2022363300 crossrefType "journal-article" @default.
- W2022363300 hasAuthorship W2022363300A5078094010 @default.
- W2022363300 hasConcept C126322002 @default.
- W2022363300 hasConcept C134018914 @default.
- W2022363300 hasConcept C143228043 @default.
- W2022363300 hasConcept C159110408 @default.
- W2022363300 hasConcept C170493617 @default.
- W2022363300 hasConcept C185592680 @default.
- W2022363300 hasConcept C202751555 @default.
- W2022363300 hasConcept C2775944032 @default.
- W2022363300 hasConcept C2776106523 @default.
- W2022363300 hasConcept C2778642596 @default.
- W2022363300 hasConcept C2779234561 @default.
- W2022363300 hasConcept C2780664492 @default.
- W2022363300 hasConcept C49453240 @default.
- W2022363300 hasConcept C54355233 @default.
- W2022363300 hasConcept C55493867 @default.
- W2022363300 hasConcept C57992300 @default.
- W2022363300 hasConcept C64943373 @default.
- W2022363300 hasConcept C71240020 @default.
- W2022363300 hasConcept C71315377 @default.
- W2022363300 hasConcept C71924100 @default.
- W2022363300 hasConcept C86803240 @default.
- W2022363300 hasConcept C98274493 @default.
- W2022363300 hasConceptScore W2022363300C126322002 @default.
- W2022363300 hasConceptScore W2022363300C134018914 @default.
- W2022363300 hasConceptScore W2022363300C143228043 @default.
- W2022363300 hasConceptScore W2022363300C159110408 @default.
- W2022363300 hasConceptScore W2022363300C170493617 @default.
- W2022363300 hasConceptScore W2022363300C185592680 @default.
- W2022363300 hasConceptScore W2022363300C202751555 @default.
- W2022363300 hasConceptScore W2022363300C2775944032 @default.
- W2022363300 hasConceptScore W2022363300C2776106523 @default.
- W2022363300 hasConceptScore W2022363300C2778642596 @default.
- W2022363300 hasConceptScore W2022363300C2779234561 @default.
- W2022363300 hasConceptScore W2022363300C2780664492 @default.
- W2022363300 hasConceptScore W2022363300C49453240 @default.
- W2022363300 hasConceptScore W2022363300C54355233 @default.
- W2022363300 hasConceptScore W2022363300C55493867 @default.
- W2022363300 hasConceptScore W2022363300C57992300 @default.
- W2022363300 hasConceptScore W2022363300C64943373 @default.
- W2022363300 hasConceptScore W2022363300C71240020 @default.
- W2022363300 hasConceptScore W2022363300C71315377 @default.
- W2022363300 hasConceptScore W2022363300C71924100 @default.
- W2022363300 hasConceptScore W2022363300C86803240 @default.
- W2022363300 hasConceptScore W2022363300C98274493 @default.
- W2022363300 hasIssue "1" @default.
- W2022363300 hasLocation W20223633001 @default.
- W2022363300 hasLocation W20223633002 @default.
- W2022363300 hasOpenAccess W2022363300 @default.
- W2022363300 hasPrimaryLocation W20223633001 @default.
- W2022363300 hasRelatedWork W1566419909 @default.
- W2022363300 hasRelatedWork W1963919935 @default.
- W2022363300 hasRelatedWork W1965699720 @default.
- W2022363300 hasRelatedWork W2015560083 @default.
- W2022363300 hasRelatedWork W2020167192 @default.
- W2022363300 hasRelatedWork W2032428603 @default.
- W2022363300 hasRelatedWork W2043899786 @default.
- W2022363300 hasRelatedWork W2063619316 @default.
- W2022363300 hasRelatedWork W2083415808 @default.
- W2022363300 hasRelatedWork W2090757166 @default.
- W2022363300 hasVolume "44" @default.
- W2022363300 isParatext "false" @default.
- W2022363300 isRetracted "false" @default.
- W2022363300 magId "2022363300" @default.
- W2022363300 workType "article" @default.