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• W2022363338 abstract "During an immune response, peripheral T cells develop into functionally distinct subpopulations that effect cell-mediated immunity and regulate humoral immune responses through the secretion of specific cytokines. Recent data suggest that CD8 T cells, which have long been regarded simply as cytotoxic cells, play a more active role in the regulation of the immune response. In this article, Mike Kemeny and colleagues suggest that there are functionally distinct subsets of CD8 T cells that produce different combinations of cytokines and appear to play an important part in determining the pattern of cytokines produced by CD4 T cells and the isotype of immunoglobulins expressed by B cells." @default.
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• W2022363338 date "1994-03-01" @default.
• W2022363338 modified "2023-09-23" @default.
• W2022363338 title "Immune regulation: a new role for the CD8+ T cell" @default.
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• W2022363338 doi "https://doi.org/10.1016/0167-5699(94)90152-x" @default.
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