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• W2022370280 abstract "Leukocyte telomere length (LTL) and bone mineral density (BMD) are associated with health and mortality. Because osteoporosis is an age-related condition and LTL is considered to be a biomarker of aging, we hypothesized that shorter LTL could predict lower BMD. The aim of our study was to assess whether there is an association of LTL with BMD and to determine whether this possible association is independent of age. The BMDs of the lumbar spine (LS), femoral neck (FN) and total hip (TH) were evaluated in 460 women using DXA. LTL was analyzed using quantitative polymerase chain reaction. The women completed a health and lifestyle questionnaire. The associations were estimated by regression models that considered age, body mass index (BMI), menopause, physical activity, alcohol consumption and smoking habits. We found a statistically significant unadjusted association between LTL and age (estimate and 95% confidence interval (CI): − 0.003 (− 0.005; − 0.002)); and between BMI adjusted age and logarithmic transformed BMD. Estimates and 95% CI were as follows: LS: − 0.13 (− 0.26; − 0.01); right TH: − 0.44 (− 0.53; − 0.34); left TH: − 0.38 (− 0.48; − 0.28); right FN: − 0.57 (− 0.67; − 0.46) and left FN: − 0.51 (− 0.62; − 0.40). There were no statistically significant associations between BMD and LTL (both logarithmically transformed) with or without age adjustments. The age-adjusted estimates and CI were as follows: LS: − 0.10 (− 0.71; 0.52); right TH: − 0.13 (− 0.66; 0.41); left TH: − 0.13 (− 0.67; 0.42); right FN: − 0.03 (− 0.58; 0.52) and left FN: 0.09 (− 0.47; 0.66). In conclusion, we found no statistically significant associations between BMD and LTL, although the estimates of the crude associations were all positive, indicating hypothesis consistency; that shorter LTL predict lower BMD values. This positive association was no longer apparent after adjusting for age. As expected, age was statistically significantly associated with both telomere length and BMI adjusted BMD." @default.
• W2022370280 created "2016-06-24" @default.
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• W2022370280 date "2015-06-01" @default.
• W2022370280 modified "2023-10-18" @default.
• W2022370280 title "Association between leukocyte telomere length and bone mineral density in women 25–93years of age" @default.
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• W2022370280 cites W1964977047 @default.
• W2022370280 cites W1965364326 @default.
• W2022370280 cites W1969416181 @default.
• W2022370280 cites W1970895749 @default.
• W2022370280 cites W1971459681 @default.
• W2022370280 cites W1975750369 @default.
• W2022370280 cites W1983673827 @default.
• W2022370280 cites W1986602198 @default.
• W2022370280 cites W1990822552 @default.
• W2022370280 cites W1994404511 @default.
• W2022370280 cites W1998609861 @default.
• W2022370280 cites W1998663807 @default.
• W2022370280 cites W2010923244 @default.
• W2022370280 cites W2015536677 @default.
• W2022370280 cites W2015795623 @default.
• W2022370280 cites W2017218670 @default.
• W2022370280 cites W2017895646 @default.
• W2022370280 cites W2023323669 @default.
• W2022370280 cites W2026761826 @default.
• W2022370280 cites W2027446722 @default.
• W2022370280 cites W2027884659 @default.
• W2022370280 cites W2032955267 @default.
• W2022370280 cites W2034656280 @default.
• W2022370280 cites W2043021712 @default.
• W2022370280 cites W2052659218 @default.
• W2022370280 cites W2058799324 @default.
• W2022370280 cites W2062395030 @default.
• W2022370280 cites W2063257115 @default.
• W2022370280 cites W2065071105 @default.
• W2022370280 cites W2067586128 @default.
• W2022370280 cites W2071961084 @default.
• W2022370280 cites W2075387442 @default.
• W2022370280 cites W2078786713 @default.
• W2022370280 cites W2081327669 @default.
• W2022370280 cites W2083439327 @default.
• W2022370280 cites W2086807576 @default.
• W2022370280 cites W2088672106 @default.
• W2022370280 cites W2091267313 @default.
• W2022370280 cites W2092476887 @default.
• W2022370280 cites W2094376145 @default.
• W2022370280 cites W2098586364 @default.
• W2022370280 cites W2101872269 @default.
• W2022370280 cites W2102734197 @default.
• W2022370280 cites W2105637995 @default.
• W2022370280 cites W2109912666 @default.
• W2022370280 cites W2114045481 @default.
• W2022370280 cites W2114919699 @default.
• W2022370280 cites W2117902460 @default.
• W2022370280 cites W2124157902 @default.
• W2022370280 cites W2127367027 @default.
• W2022370280 cites W2132931629 @default.
• W2022370280 cites W2133750711 @default.
• W2022370280 cites W2139688955 @default.
• W2022370280 cites W2140847067 @default.
• W2022370280 cites W2143471290 @default.
• W2022370280 cites W2145331177 @default.
• W2022370280 cites W2150552736 @default.
• W2022370280 cites W2153827064 @default.
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• W2022370280 cites W2160621707 @default.
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• W2022370280 cites W2164808240 @default.
• W2022370280 cites W2167285829 @default.
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• W2022370280 doi "https://doi.org/10.1016/j.exger.2015.04.004" @default.
• W2022370280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25868397" @default.
• W2022370280 hasPublicationYear "2015" @default.
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