Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022376520> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2022376520 endingPage "1835" @default.
- W2022376520 startingPage "1833" @default.
- W2022376520 abstract "The effects of benztropine mesylate on haloperidol-induced prolactin secretion and serum haloperidol levels were investigated in 240 rats. Animals were pretreated with benztropine mesylate or saline 20 min prior to receiving haloperidol or saline. Serum prolactin and haloperidol levels were analyzed at six time periods over 150 min. There was no significant difference in prolactin levels of control animals, i.e., saline pretreated/saline treated rats compared to benztropine mesylate pretreated/saline treated rats. Haloperidol caused a significant rise (p < 0.0001) in serum prolactin compared with controls. The prolactin concentration for the 30–150-min sampling period was significantly higher when the rats received benztropine mesylate prior to haloperidol (p < 0.05). There was a significant correlation (r = 0.57, p < 0.001) between serum haloperidol levels and serum prolactin levels in haloperidol-treated animals pretreated with either saline or benztropine mesylate. Additionally, serum haloperidol levels were not significantly different in animals pretreated with benztropine mesylate compared with those pretreated with saline. Thus, the enhancement of prolactin levels by benztropine mesylate was independent of any effect of haloperidol metabolism. This study appears to indicate that in the rat, cholinergic mechanisms exert a weak inhibitory effect on prolactin secretion under conditions of dopamine blockade." @default.
- W2022376520 created "2016-06-24" @default.
- W2022376520 creator A5038448839 @default.
- W2022376520 creator A5062856772 @default.
- W2022376520 creator A5084597999 @default.
- W2022376520 creator A5087508452 @default.
- W2022376520 creator A5087716073 @default.
- W2022376520 date "1984-12-01" @default.
- W2022376520 modified "2023-09-25" @default.
- W2022376520 title "Effects of Benztropine Mesylate on Haloperidol-Induced Prolactin Secretion and Serum Haloperidol Levels in Rats" @default.
- W2022376520 cites W1968737787 @default.
- W2022376520 cites W1989034225 @default.
- W2022376520 cites W1989314580 @default.
- W2022376520 cites W1997257276 @default.
- W2022376520 cites W2000652762 @default.
- W2022376520 cites W2007954498 @default.
- W2022376520 cites W2010941117 @default.
- W2022376520 cites W2016487214 @default.
- W2022376520 cites W2027127607 @default.
- W2022376520 cites W2031843295 @default.
- W2022376520 cites W2033785962 @default.
- W2022376520 cites W2038765068 @default.
- W2022376520 cites W2041818137 @default.
- W2022376520 cites W2047335368 @default.
- W2022376520 cites W2050263686 @default.
- W2022376520 cites W2056219222 @default.
- W2022376520 cites W2063758618 @default.
- W2022376520 cites W2065675231 @default.
- W2022376520 cites W2092416470 @default.
- W2022376520 cites W2101466720 @default.
- W2022376520 cites W2113645921 @default.
- W2022376520 cites W2117245535 @default.
- W2022376520 cites W2134929591 @default.
- W2022376520 cites W2149439262 @default.
- W2022376520 cites W2149587713 @default.
- W2022376520 doi "https://doi.org/10.1002/jps.2600731247" @default.
- W2022376520 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6527272" @default.
- W2022376520 hasPublicationYear "1984" @default.
- W2022376520 type Work @default.
- W2022376520 sameAs 2022376520 @default.
- W2022376520 citedByCount "1" @default.
- W2022376520 crossrefType "journal-article" @default.
- W2022376520 hasAuthorship W2022376520A5038448839 @default.
- W2022376520 hasAuthorship W2022376520A5062856772 @default.
- W2022376520 hasAuthorship W2022376520A5084597999 @default.
- W2022376520 hasAuthorship W2022376520A5087508452 @default.
- W2022376520 hasAuthorship W2022376520A5087716073 @default.
- W2022376520 hasConcept C126322002 @default.
- W2022376520 hasConcept C134018914 @default.
- W2022376520 hasConcept C178790620 @default.
- W2022376520 hasConcept C185592680 @default.
- W2022376520 hasConcept C2777397205 @default.
- W2022376520 hasConcept C2779064019 @default.
- W2022376520 hasConcept C2780194963 @default.
- W2022376520 hasConcept C2780948584 @default.
- W2022376520 hasConcept C2910393698 @default.
- W2022376520 hasConcept C513476851 @default.
- W2022376520 hasConcept C71315377 @default.
- W2022376520 hasConcept C71924100 @default.
- W2022376520 hasConcept C98274493 @default.
- W2022376520 hasConceptScore W2022376520C126322002 @default.
- W2022376520 hasConceptScore W2022376520C134018914 @default.
- W2022376520 hasConceptScore W2022376520C178790620 @default.
- W2022376520 hasConceptScore W2022376520C185592680 @default.
- W2022376520 hasConceptScore W2022376520C2777397205 @default.
- W2022376520 hasConceptScore W2022376520C2779064019 @default.
- W2022376520 hasConceptScore W2022376520C2780194963 @default.
- W2022376520 hasConceptScore W2022376520C2780948584 @default.
- W2022376520 hasConceptScore W2022376520C2910393698 @default.
- W2022376520 hasConceptScore W2022376520C513476851 @default.
- W2022376520 hasConceptScore W2022376520C71315377 @default.
- W2022376520 hasConceptScore W2022376520C71924100 @default.
- W2022376520 hasConceptScore W2022376520C98274493 @default.
- W2022376520 hasIssue "12" @default.
- W2022376520 hasLocation W20223765201 @default.
- W2022376520 hasLocation W20223765202 @default.
- W2022376520 hasOpenAccess W2022376520 @default.
- W2022376520 hasPrimaryLocation W20223765201 @default.
- W2022376520 hasRelatedWork W1969139594 @default.
- W2022376520 hasRelatedWork W2006797593 @default.
- W2022376520 hasRelatedWork W2017638447 @default.
- W2022376520 hasRelatedWork W2038081958 @default.
- W2022376520 hasRelatedWork W2042742532 @default.
- W2022376520 hasRelatedWork W2062579683 @default.
- W2022376520 hasRelatedWork W2066166985 @default.
- W2022376520 hasRelatedWork W2120946541 @default.
- W2022376520 hasRelatedWork W2123442016 @default.
- W2022376520 hasRelatedWork W2163744984 @default.
- W2022376520 hasVolume "73" @default.
- W2022376520 isParatext "false" @default.
- W2022376520 isRetracted "false" @default.
- W2022376520 magId "2022376520" @default.
- W2022376520 workType "article" @default.