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- W2022376905 abstract "Neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases, and apoptosis, are thought to be associated with oxidative stress affecting mitochondria. In this study, we designed and synthesized a fluorescein-tagged TEMPO derivative, compound 1, with triphenylphosphino moiety. Synthesized 1 localized in mitochondria and detected oxidative stress in an endotoxic model of a mouse macrophage-like cell line. Compound 1 is therefore a potentially useful probe for evaluating oxidative stress in mitochondria." @default.
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- W2022376905 date "2007-04-01" @default.
- W2022376905 modified "2023-09-23" @default.
- W2022376905 title "Novel mitochondria-localizing TEMPO derivative for measurement of cellular oxidative stress in mitochondria" @default.
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- W2022376905 doi "https://doi.org/10.1016/j.bmcl.2007.01.011" @default.
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