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• W2022381132 abstract "Following the original description of the cardinal motor features of Parkinson's disease described by Parkinson in England in 1817, 50 years passed before Charcot in France credited him for his recognition of the syndrome [ [1] Louis E.D. The shaking palsy, the first forty-five years: a journey through the British literature. Mov Disord. 1997; 12: 1068-1072 Crossref PubMed Scopus (10) Google Scholar ]. It was around the same time that Charcot and others first mentioned in their writings observations of intellectual decline in patients with motor symptoms of PD. Most of these descriptions characterize the mental symptoms of PD as symptoms of advanced disease [ [2] Fenelon G. Goetz C.G. Karenberg A. Hallucinations in Parkinson disease in the prelevodopa era. Neurology. 2006; 66: 93-98 Crossref PubMed Scopus (70) Google Scholar ]. It has only been in the last 25 years that the pervasiveness of the cognitive, affective, and psychiatric features of PD has been recognized. Average frequency of dementia in PD was reported as 40% in one multistudy analysis [ [3] Cummings J.L. Darkins A. Mendez M. et al. Alzheimer's disease and Parkinson's disease: comparison of speech and language alterations. Neurology. 1988; 38: 680-684 Crossref PubMed Google Scholar ], and prevalence rates range from 3% to 80%. Reports of frequency of depression range from 20% to 50% [ 4 Dooneief G. Bello J. Todak G. et al. A prospective controlled study of magnetic resonance imaging of the brain in gay men and parenteral drug users with human immunodeficiency virus infection. Arch Neurol. 1992; 49: 38-43 Crossref PubMed Google Scholar , 5 Mayeux R. Stern Y. Rosen J. et al. Depression, intellectual impairment, and Parkinson disease. Neurology. 1981; 31: 645-650 Crossref PubMed Google Scholar , 6 Tandberg E. Larsen J.P. Aarsland D. et al. The occurrence of depression in Parkinson's disease: a community-based study. Arch Neurol. 1996; 53: 175-179 Crossref PubMed Google Scholar ], and frequency of psychiatric symptoms of any type are reported at greater than 60% [ [7] Aarsland D. Larsen J.P. Lim N.G. et al. Range of neuropsychiatric disturbances in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1999; 67: 492-496 Crossref PubMed Google Scholar ]. The variability in frequency rates reported for each of these features can be explained by numerous factors that influence survey results, including differences in symptom definition, absence of uniform clinical or pathologic diagnostic criteria, and evolution in application of diagnostic techniques." @default.
• W2022381132 created "2016-06-24" @default.
• W2022381132 creator A5051294158 @default.
• W2022381132 date "2006-11-01" @default.
• W2022381132 modified "2023-10-18" @default.
• W2022381132 title "Cognitive, Affective, and Psychiatric Features of Parkinson's Disease" @default.
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