Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022383145> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2022383145 endingPage "640" @default.
- W2022383145 startingPage "634" @default.
- W2022383145 abstract "Calculations of the incidence of hepatitis B virus (HBV) infections in the blood donor setting that are based solely on data for seroconversion to hepatitis B surface antigen (HBsAg) will underestimate the incidence due to the transient nature of antigenemia. Estimates based on antibody to hepatitis B core antigen will overestimate the incidence due to false-positive results caused by the nonspecificity of the test.Serologic test results were obtained from multiple-time volunteer donors at five United States blood centers from January 1991 through December 1993. The observed HBsAg seroconversion rate was multiplied by an adjustment factor, derived from the weighted average probability of a positive HBsAg test for HBV-infected donors who become chronic carriers, for donors with a primary antibody response without detectable antigenemia, and for donors who develop transient antigenemia.Among 586,507 multiple-time donors giving 2,318,356 donations and observed for 822,426 person-years, the HBsAg incidence rate was 4.01 per 100,000 person-years. On the basis of prior reports of the duration of HBsAg positivity and the observed distribution of interdonation intervals among the study group, there was an estimated 53-percent chance that an HBV-infected donor with transient antigenemia would have a positive HBsAg test result. If 70 percent of newly HBV-infected adults have transient antigenemia, 25 percent have a primary antibody response without primary antigenemia, and 5 percent become chronic carriers, the overall chance of being detected by the HBsAg test was 42 percent, for an adjustment factor of 2.38. The total HBV incidence rate, therefore, was estimated to be 9.54 per 100,000 person-years.The crude HBV incidence rate observed from HBsAg test results will underestimate the true rate. The adjusted HBV incidence rate should be used in applications such as estimations of residual HBV risk to the blood supply and projections of the benefits of screening for HBV DNA." @default.
- W2022383145 created "2016-06-24" @default.
- W2022383145 creator A5005201781 @default.
- W2022383145 creator A5009436697 @default.
- W2022383145 creator A5022836185 @default.
- W2022383145 creator A5046246642 @default.
- W2022383145 creator A5048250843 @default.
- W2022383145 creator A5075279247 @default.
- W2022383145 creator A5087466983 @default.
- W2022383145 date "1997-06-01" @default.
- W2022383145 modified "2023-09-26" @default.
- W2022383145 title "A method for estimating hepatitis B virus incidence rates in volunteer blood donors. National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Study" @default.
- W2022383145 doi "https://doi.org/10.1046/j.1537-2995.1997.37697335159.x" @default.
- W2022383145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9191825" @default.
- W2022383145 hasPublicationYear "1997" @default.
- W2022383145 type Work @default.
- W2022383145 sameAs 2022383145 @default.
- W2022383145 citedByCount "87" @default.
- W2022383145 countsByYear W20223831452012 @default.
- W2022383145 countsByYear W20223831452013 @default.
- W2022383145 countsByYear W20223831452014 @default.
- W2022383145 countsByYear W20223831452015 @default.
- W2022383145 countsByYear W20223831452016 @default.
- W2022383145 countsByYear W20223831452017 @default.
- W2022383145 countsByYear W20223831452018 @default.
- W2022383145 countsByYear W20223831452019 @default.
- W2022383145 countsByYear W20223831452020 @default.
- W2022383145 countsByYear W20223831452021 @default.
- W2022383145 countsByYear W20223831452022 @default.
- W2022383145 crossrefType "journal-article" @default.
- W2022383145 hasAuthorship W2022383145A5005201781 @default.
- W2022383145 hasAuthorship W2022383145A5009436697 @default.
- W2022383145 hasAuthorship W2022383145A5022836185 @default.
- W2022383145 hasAuthorship W2022383145A5046246642 @default.
- W2022383145 hasAuthorship W2022383145A5048250843 @default.
- W2022383145 hasAuthorship W2022383145A5075279247 @default.
- W2022383145 hasAuthorship W2022383145A5087466983 @default.
- W2022383145 hasConcept C107130276 @default.
- W2022383145 hasConcept C120665830 @default.
- W2022383145 hasConcept C121332964 @default.
- W2022383145 hasConcept C126322002 @default.
- W2022383145 hasConcept C159047783 @default.
- W2022383145 hasConcept C159654299 @default.
- W2022383145 hasConcept C203014093 @default.
- W2022383145 hasConcept C2522874641 @default.
- W2022383145 hasConcept C2776768635 @default.
- W2022383145 hasConcept C2777382497 @default.
- W2022383145 hasConcept C2777410769 @default.
- W2022383145 hasConcept C2777451964 @default.
- W2022383145 hasConcept C2780593183 @default.
- W2022383145 hasConcept C45189115 @default.
- W2022383145 hasConcept C61511704 @default.
- W2022383145 hasConcept C6557445 @default.
- W2022383145 hasConcept C71924100 @default.
- W2022383145 hasConcept C86803240 @default.
- W2022383145 hasConcept C90924648 @default.
- W2022383145 hasConceptScore W2022383145C107130276 @default.
- W2022383145 hasConceptScore W2022383145C120665830 @default.
- W2022383145 hasConceptScore W2022383145C121332964 @default.
- W2022383145 hasConceptScore W2022383145C126322002 @default.
- W2022383145 hasConceptScore W2022383145C159047783 @default.
- W2022383145 hasConceptScore W2022383145C159654299 @default.
- W2022383145 hasConceptScore W2022383145C203014093 @default.
- W2022383145 hasConceptScore W2022383145C2522874641 @default.
- W2022383145 hasConceptScore W2022383145C2776768635 @default.
- W2022383145 hasConceptScore W2022383145C2777382497 @default.
- W2022383145 hasConceptScore W2022383145C2777410769 @default.
- W2022383145 hasConceptScore W2022383145C2777451964 @default.
- W2022383145 hasConceptScore W2022383145C2780593183 @default.
- W2022383145 hasConceptScore W2022383145C45189115 @default.
- W2022383145 hasConceptScore W2022383145C61511704 @default.
- W2022383145 hasConceptScore W2022383145C6557445 @default.
- W2022383145 hasConceptScore W2022383145C71924100 @default.
- W2022383145 hasConceptScore W2022383145C86803240 @default.
- W2022383145 hasConceptScore W2022383145C90924648 @default.
- W2022383145 hasIssue "6" @default.
- W2022383145 hasLocation W20223831451 @default.
- W2022383145 hasLocation W20223831452 @default.
- W2022383145 hasOpenAccess W2022383145 @default.
- W2022383145 hasPrimaryLocation W20223831451 @default.
- W2022383145 hasRelatedWork W1506797373 @default.
- W2022383145 hasRelatedWork W1986044171 @default.
- W2022383145 hasRelatedWork W2006079246 @default.
- W2022383145 hasRelatedWork W2022383145 @default.
- W2022383145 hasRelatedWork W2028125236 @default.
- W2022383145 hasRelatedWork W2031837263 @default.
- W2022383145 hasRelatedWork W2059888761 @default.
- W2022383145 hasRelatedWork W2061734351 @default.
- W2022383145 hasRelatedWork W2588441876 @default.
- W2022383145 hasRelatedWork W3128830683 @default.
- W2022383145 hasVolume "37" @default.
- W2022383145 isParatext "false" @default.
- W2022383145 isRetracted "false" @default.
- W2022383145 magId "2022383145" @default.
- W2022383145 workType "article" @default.