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• W2022383636 abstract "In order to prepare a new delivery system by chemical modification, peptide–siRNA conjugates have been obtained by a solid-phase click chemistry strategy, using an alkynyl nucleoside analogue “clicked” onto a peptide-derivatized CPG (Controlled Pore Glass) followed by oligonucleotides synthesis. The 3′-sense strand conjugate maintained good gene silencing activity, while that of the 3′-antisense strand conjugate decreased somewhat." @default.
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• W2022383636 date "2012-01-01" @default.
• W2022383636 modified "2023-09-24" @default.
• W2022383636 title "A solid-phase method for peptide–siRNA covalent conjugates based on click chemistry" @default.
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• W2022383636 doi "https://doi.org/10.1039/c2md00198e" @default.
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