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• W2022385313 abstract "Clostridium perfringens isolates are currently classified into one of five biotypes on the basis of the differential production of alpha-, beta-, epsilon- and iota-toxins. Different biotypes are associated with different diseases of man and animals. In this study a multiple PCR assay was developed to detect the genes encoding these toxins. In addition, detection of the genes encoding the C. perfringens enterotoxin and beta2-toxin allowed subtyping of the bacteria. C. perfringens isolates taken from a variety of animals, including foals, piglets or lambs, were genotyped using this assay. Most of the isolates were found to be genotype A and the gene encoding beta2-toxin [corrected] was present in 50% of the isolates genotyped. A significant association between C. perfringens possessing the beta2-toxin gene and diarrhoea in piglets was identified, suggesting that beta2-toxin may play a key role in the pathogenesis of the disease." @default.
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• W2022385313 date "2000-02-01" @default.
• W2022385313 modified "2023-10-16" @default.
• W2022385313 title "Occurrence of <i>Clostridium perfringens</i> β2-toxin amongst animals, determined using genotyping and subtyping PCR assays" @default.
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• W2022385313 doi "https://doi.org/10.1017/s0950268899003295" @default.
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