FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022385446> ?p ?o ?g. }

• W2022385446 endingPage "589" @default.
• W2022385446 startingPage "582" @default.
• W2022385446 abstract "Appetite and eating are not only controlled by energy needs, but also by extrinsic factors that are not directly related to energy balance. Environmental signals that acquire motivational properties through associative learning—learned cues—can override homeostatic signals and stimulate eating in sated states, or inhibit eating in states of hunger. Such influences are important, as environmental factors are believed to contribute to the increased susceptibility to overeating and the rise in obesity in the developed world. Similarly, environmental and social factors contribute to the onset and maintenance of anorexia nervosa and other eating disorders through interactions with the individual genetic background. Nevertheless, how learning enables environmental signals to control feeding, and the underlying brain mechanisms are poorly understood. We developed two rodent models to study how learned cues are integrated with homeostatic signals within functional forebrain networks, and how these networks are modulated by experience. In one model, a cue previously paired with food when an animal was hungry induces eating in sated rats. In the other model, food-deprived rats inhibit feeding when presented with a cue that signals danger, a tone previously paired with footshocks. Here evidence will be reviewed that the forebrain network formed by the amygdala, lateral hypothalamus and medial prefrontal cortex mediates cue-driven feeding, while a parallel amygdalar circuitry mediates suppression of eating by the fear cue. Findings from the animal models may be relevant for understanding aspects of human appetite and eating, and maladaptive mechanisms that could lead to overeating and anorexia." @default.
• W2022385446 created "2016-06-24" @default.
• W2022385446 creator A5048647330 @default.
• W2022385446 date "2011-09-01" @default.
• W2022385446 modified "2023-10-12" @default.
• W2022385446 title "Learning and the motivation to eat: Forebrain circuitry" @default.
• W2022385446 cites W14659034 @default.
• W2022385446 cites W1481893565 @default.
• W2022385446 cites W1513605896 @default.
• W2022385446 cites W1561443084 @default.
• W2022385446 cites W1566047568 @default.
• W2022385446 cites W1577992062 @default.
• W2022385446 cites W1900979097 @default.
• W2022385446 cites W1956210168 @default.
• W2022385446 cites W1965460325 @default.
• W2022385446 cites W1966760583 @default.
• W2022385446 cites W1966793802 @default.
• W2022385446 cites W1969305409 @default.
• W2022385446 cites W1972251813 @default.
• W2022385446 cites W1973752193 @default.
• W2022385446 cites W1974023979 @default.
• W2022385446 cites W1976117761 @default.
• W2022385446 cites W1976999450 @default.
• W2022385446 cites W1978330600 @default.
• W2022385446 cites W1978686333 @default.
• W2022385446 cites W1980197461 @default.
• W2022385446 cites W1980321165 @default.
• W2022385446 cites W1980497606 @default.
• W2022385446 cites W1980866164 @default.
• W2022385446 cites W1981282969 @default.
• W2022385446 cites W1981407855 @default.
• W2022385446 cites W1984727050 @default.
• W2022385446 cites W1985651588 @default.
• W2022385446 cites W1986570714 @default.
• W2022385446 cites W1986802481 @default.
• W2022385446 cites W1987979728 @default.
• W2022385446 cites W1990388529 @default.
• W2022385446 cites W1990956863 @default.
• W2022385446 cites W1992061204 @default.
• W2022385446 cites W1993137505 @default.
• W2022385446 cites W1994955948 @default.
• W2022385446 cites W1997183808 @default.
• W2022385446 cites W1998982008 @default.
• W2022385446 cites W2003249940 @default.
• W2022385446 cites W2003846166 @default.
• W2022385446 cites W2004552390 @default.
• W2022385446 cites W2006280142 @default.
• W2022385446 cites W2008106418 @default.
• W2022385446 cites W2009189044 @default.
• W2022385446 cites W2011377540 @default.
• W2022385446 cites W2012222816 @default.
• W2022385446 cites W2012483271 @default.
• W2022385446 cites W2013586816 @default.
• W2022385446 cites W2014781237 @default.
• W2022385446 cites W2017423317 @default.
• W2022385446 cites W2017517270 @default.
• W2022385446 cites W2017934537 @default.
• W2022385446 cites W2020695426 @default.
• W2022385446 cites W2021721995 @default.
• W2022385446 cites W2021990516 @default.
• W2022385446 cites W2022816630 @default.
• W2022385446 cites W2023516685 @default.
• W2022385446 cites W2023729117 @default.
• W2022385446 cites W2024375723 @default.
• W2022385446 cites W2025039841 @default.
• W2022385446 cites W2027159964 @default.
• W2022385446 cites W2027180375 @default.
• W2022385446 cites W2027740042 @default.
• W2022385446 cites W2028866038 @default.
• W2022385446 cites W2029119693 @default.
• W2022385446 cites W2029484301 @default.
• W2022385446 cites W2033316597 @default.
• W2022385446 cites W2035630779 @default.
• W2022385446 cites W2035675009 @default.
• W2022385446 cites W2037335834 @default.
• W2022385446 cites W2040527392 @default.
• W2022385446 cites W2041710499 @default.
• W2022385446 cites W2042847262 @default.
• W2022385446 cites W2044150847 @default.
• W2022385446 cites W2044496457 @default.
• W2022385446 cites W2045948521 @default.
• W2022385446 cites W2047172322 @default.
• W2022385446 cites W2048817529 @default.
• W2022385446 cites W2048971518 @default.
• W2022385446 cites W2049392123 @default.
• W2022385446 cites W2051613659 @default.
• W2022385446 cites W2056415796 @default.
• W2022385446 cites W2058776784 @default.
• W2022385446 cites W2061478482 @default.
• W2022385446 cites W2067387489 @default.
• W2022385446 cites W2068092467 @default.
• W2022385446 cites W2069416181 @default.
• W2022385446 cites W2069600955 @default.
• W2022385446 cites W2074382500 @default.
• W2022385446 cites W2074617349 @default.
• W2022385446 cites W2075068794 @default.
• W2022385446 cites W2075110848 @default.
• W2022385446 cites W2078850444 @default.

• next