Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022386781> ?p ?o ?g. }
- W2022386781 endingPage "292" @default.
- W2022386781 startingPage "273" @default.
- W2022386781 abstract "Age-related alterations in both antioxidant capacity and lipid peroxidation in the cerebrum, lung and liver homogenates of normal and vitamin E-deficient rats were investigated. The antioxidant capacity, which includes superoxide dismutase, catalase and glutathione peroxidase activities and vitamin E (alpha-tocopherol) concentration, was relatively stable throughout the lifespan. It was observed, however, that catalase and glutathione peroxidase activities in livers of old rats decreased and that vitamin E concentration in lung and liver increased with age. In vitamin E-deficient animals, catalase activity in liver increased and glutathione peroxidase activity in liver and lung decreased. Lipid peroxidation was monitored by use of three different indices, i.e. the thiobarbituric acid (TBA) value, oxygen absorption and conjugated-diene formation. In the absence of any initiator, neither oxygen absorption into tissue homogenates nor conjugated-diene formation in lipid extracts from the homogenates occurred. The TBA value of each cerebrum homogenate incubated under air or an oxygen atmosphere was larger than that of the corresponding unincubated cerebrum homogenate. From comparison between the TBA value and oxygen absorption, this increase in the TBA value was suggested to be due to some reactions other than lipid peroxidation. Although tissue homogenates examined contained TBA-reacting materials, no lipid peroxidation seems to arise during incubation of them. No age-related alterations in the TBA value and oxygen absorption in rat tissue homogenates were observed. Vitamin E deficiency had no effect on the TBA values of cerebrum and lung homogenates, while it seemed to increase the TBA values of liver homogenates. Vitamin E deficiency had no effect on oxygen absorption in these tissue homogenates. The induction period of initiator-induced conjugated-diene formation in lipid extracts from liver and lung homogenates from normal and vitamin E-deficient rats tended to be extended with age. Vitamin E deficiency decreased the induction period of initiator-induced conjugated-diene formation. As a result, the length of the induction period was found to be proportional to vitamin E concentration in lipid extracts. The overall antioxidant capacity of rat tissues appears to be maintained without large variation during ageing. Decreases in the capacity of some antioxidant factors may be compensated by increases in the capacity of other factors." @default.
- W2022386781 created "2016-06-24" @default.
- W2022386781 creator A5069820503 @default.
- W2022386781 creator A5081573218 @default.
- W2022386781 creator A5090262566 @default.
- W2022386781 date "1992-07-01" @default.
- W2022386781 modified "2023-09-25" @default.
- W2022386781 title "Age-related alterations in antioxidant capacity and lipid peroxidation in brain, liver, and lung homogenates of normal and vitamin E-deficient rats" @default.
- W2022386781 cites W1482280407 @default.
- W2022386781 cites W1520172501 @default.
- W2022386781 cites W1533016355 @default.
- W2022386781 cites W1546592314 @default.
- W2022386781 cites W1794621064 @default.
- W2022386781 cites W186344272 @default.
- W2022386781 cites W191793640 @default.
- W2022386781 cites W1935339402 @default.
- W2022386781 cites W1968078721 @default.
- W2022386781 cites W1974238226 @default.
- W2022386781 cites W1974414259 @default.
- W2022386781 cites W1977200700 @default.
- W2022386781 cites W1977248505 @default.
- W2022386781 cites W1977505338 @default.
- W2022386781 cites W1979279600 @default.
- W2022386781 cites W2004039119 @default.
- W2022386781 cites W2009426634 @default.
- W2022386781 cites W2010004460 @default.
- W2022386781 cites W2011282129 @default.
- W2022386781 cites W2012493547 @default.
- W2022386781 cites W2016244372 @default.
- W2022386781 cites W2018603115 @default.
- W2022386781 cites W2021251341 @default.
- W2022386781 cites W2024976863 @default.
- W2022386781 cites W2026610291 @default.
- W2022386781 cites W2026734260 @default.
- W2022386781 cites W2027083704 @default.
- W2022386781 cites W2034467957 @default.
- W2022386781 cites W2034878913 @default.
- W2022386781 cites W2037524236 @default.
- W2022386781 cites W2043554708 @default.
- W2022386781 cites W2047806936 @default.
- W2022386781 cites W2048167413 @default.
- W2022386781 cites W2051289202 @default.
- W2022386781 cites W2053054955 @default.
- W2022386781 cites W2055362731 @default.
- W2022386781 cites W2062552045 @default.
- W2022386781 cites W2069978441 @default.
- W2022386781 cites W2075417836 @default.
- W2022386781 cites W2076710091 @default.
- W2022386781 cites W2083622913 @default.
- W2022386781 cites W2091307204 @default.
- W2022386781 cites W2321022614 @default.
- W2022386781 cites W2414379068 @default.
- W2022386781 doi "https://doi.org/10.1016/0047-6374(92)90084-q" @default.
- W2022386781 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1405785" @default.
- W2022386781 hasPublicationYear "1992" @default.
- W2022386781 type Work @default.
- W2022386781 sameAs 2022386781 @default.
- W2022386781 citedByCount "83" @default.
- W2022386781 countsByYear W20223867812012 @default.
- W2022386781 countsByYear W20223867812013 @default.
- W2022386781 countsByYear W20223867812014 @default.
- W2022386781 countsByYear W20223867812017 @default.
- W2022386781 countsByYear W20223867812018 @default.
- W2022386781 countsByYear W20223867812019 @default.
- W2022386781 countsByYear W20223867812022 @default.
- W2022386781 crossrefType "journal-article" @default.
- W2022386781 hasAuthorship W2022386781A5069820503 @default.
- W2022386781 hasAuthorship W2022386781A5081573218 @default.
- W2022386781 hasAuthorship W2022386781A5090262566 @default.
- W2022386781 hasConcept C126322002 @default.
- W2022386781 hasConcept C134018914 @default.
- W2022386781 hasConcept C181199279 @default.
- W2022386781 hasConcept C185592680 @default.
- W2022386781 hasConcept C2775838275 @default.
- W2022386781 hasConcept C2776940978 @default.
- W2022386781 hasConcept C2777551382 @default.
- W2022386781 hasConcept C2778004101 @default.
- W2022386781 hasConcept C2778387500 @default.
- W2022386781 hasConcept C2778760513 @default.
- W2022386781 hasConcept C2778979269 @default.
- W2022386781 hasConcept C2780829032 @default.
- W2022386781 hasConcept C538909803 @default.
- W2022386781 hasConcept C55493867 @default.
- W2022386781 hasConcept C71924100 @default.
- W2022386781 hasConcept C86803240 @default.
- W2022386781 hasConceptScore W2022386781C126322002 @default.
- W2022386781 hasConceptScore W2022386781C134018914 @default.
- W2022386781 hasConceptScore W2022386781C181199279 @default.
- W2022386781 hasConceptScore W2022386781C185592680 @default.
- W2022386781 hasConceptScore W2022386781C2775838275 @default.
- W2022386781 hasConceptScore W2022386781C2776940978 @default.
- W2022386781 hasConceptScore W2022386781C2777551382 @default.
- W2022386781 hasConceptScore W2022386781C2778004101 @default.
- W2022386781 hasConceptScore W2022386781C2778387500 @default.
- W2022386781 hasConceptScore W2022386781C2778760513 @default.
- W2022386781 hasConceptScore W2022386781C2778979269 @default.
- W2022386781 hasConceptScore W2022386781C2780829032 @default.
- W2022386781 hasConceptScore W2022386781C538909803 @default.