Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022387340> ?p ?o ?g. }
- W2022387340 endingPage "105" @default.
- W2022387340 startingPage "97" @default.
- W2022387340 abstract "This study is focused on the preparation of Ibuprofen (IBU) loaded micrometer-sized poly(lactic-co-glycolic acid) (PLGA) microspheres and process variables on the size, drug loading and release during preparation of formulation. Silicon dioxide (SiO2) nanoparticle-coated PLGA microspheres were fabricated via a combined system of “Pickering-type” emulsion route and solvent volatilization method in the absence of any molecular surfactants. Stable oil-in-water emulsions were prepared using SiO2 nanoparticles as a particulate emulsifier and a dichloromethane (CH2Cl2) solution of PLGA as an oil phase. The SiO2 nanoparticle-coated PLGA microspheres were fabricated by the evaporation of CH2Cl2 in situ, and then bare-PLGA microspheres were prepared by removal of the SiO2 nanoparticles using HF aqueous solution. The two types of microspheres were characterized in terms of size, component and morphology using scanning electronic microscope (SEM), Fourier-transform infrared, optical microscope, and so on. Moreover, IBU was encapsulated into the hybrid beads by dispersing them in the CH2Cl2 solution of PLGA in the fabrication process. The sustained release could be obtained due to the barrier of the polymeric matrix (PLGA). More over, the release curves were nicely fitted by the Weibull equation and the release followed Fickian diffusion. The combined system of Pickering emulsion and solvent volatilization opens up a new route to fabricate a variety of microspheres. The resulting microspheres may find applications as delivery vehicles for biomolecules, drugs, cosmetics and living cells." @default.
- W2022387340 created "2016-06-24" @default.
- W2022387340 creator A5013426432 @default.
- W2022387340 creator A5013722616 @default.
- W2022387340 creator A5014236711 @default.
- W2022387340 creator A5020641370 @default.
- W2022387340 creator A5058930550 @default.
- W2022387340 date "2012-03-01" @default.
- W2022387340 modified "2023-10-16" @default.
- W2022387340 title "Facile fabrication of biocompatible PLGA drug-carrying microspheres by O/W pickering emulsions" @default.
- W2022387340 cites W1968885897 @default.
- W2022387340 cites W1971339046 @default.
- W2022387340 cites W1971995275 @default.
- W2022387340 cites W1983473009 @default.
- W2022387340 cites W1987526646 @default.
- W2022387340 cites W1992153674 @default.
- W2022387340 cites W1995418081 @default.
- W2022387340 cites W1998383205 @default.
- W2022387340 cites W1999976043 @default.
- W2022387340 cites W2002798467 @default.
- W2022387340 cites W2003764754 @default.
- W2022387340 cites W2013736194 @default.
- W2022387340 cites W2015639818 @default.
- W2022387340 cites W2015838055 @default.
- W2022387340 cites W2017137997 @default.
- W2022387340 cites W2023902038 @default.
- W2022387340 cites W2028424052 @default.
- W2022387340 cites W2029255146 @default.
- W2022387340 cites W2034571177 @default.
- W2022387340 cites W2041204432 @default.
- W2022387340 cites W2046281591 @default.
- W2022387340 cites W2047210259 @default.
- W2022387340 cites W2048912731 @default.
- W2022387340 cites W2054775748 @default.
- W2022387340 cites W2063849711 @default.
- W2022387340 cites W2069591439 @default.
- W2022387340 cites W2079687116 @default.
- W2022387340 cites W2087020662 @default.
- W2022387340 cites W2090853173 @default.
- W2022387340 cites W2092248610 @default.
- W2022387340 cites W2092642103 @default.
- W2022387340 cites W2114035952 @default.
- W2022387340 cites W2115439624 @default.
- W2022387340 cites W2138429667 @default.
- W2022387340 cites W2165741791 @default.
- W2022387340 cites W2278233976 @default.
- W2022387340 cites W263675887 @default.
- W2022387340 cites W2727420541 @default.
- W2022387340 cites W4211147424 @default.
- W2022387340 doi "https://doi.org/10.1016/j.colsurfb.2011.10.044" @default.
- W2022387340 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22088755" @default.
- W2022387340 hasPublicationYear "2012" @default.
- W2022387340 type Work @default.
- W2022387340 sameAs 2022387340 @default.
- W2022387340 citedByCount "45" @default.
- W2022387340 countsByYear W20223873402012 @default.
- W2022387340 countsByYear W20223873402013 @default.
- W2022387340 countsByYear W20223873402014 @default.
- W2022387340 countsByYear W20223873402015 @default.
- W2022387340 countsByYear W20223873402016 @default.
- W2022387340 countsByYear W20223873402017 @default.
- W2022387340 countsByYear W20223873402018 @default.
- W2022387340 countsByYear W20223873402019 @default.
- W2022387340 countsByYear W20223873402020 @default.
- W2022387340 countsByYear W20223873402021 @default.
- W2022387340 countsByYear W20223873402022 @default.
- W2022387340 countsByYear W20223873402023 @default.
- W2022387340 crossrefType "journal-article" @default.
- W2022387340 hasAuthorship W2022387340A5013426432 @default.
- W2022387340 hasAuthorship W2022387340A5013722616 @default.
- W2022387340 hasAuthorship W2022387340A5014236711 @default.
- W2022387340 hasAuthorship W2022387340A5020641370 @default.
- W2022387340 hasAuthorship W2022387340A5058930550 @default.
- W2022387340 hasConcept C127413603 @default.
- W2022387340 hasConcept C155672457 @default.
- W2022387340 hasConcept C171250308 @default.
- W2022387340 hasConcept C192562407 @default.
- W2022387340 hasConcept C2778123984 @default.
- W2022387340 hasConcept C2779820397 @default.
- W2022387340 hasConcept C2780165375 @default.
- W2022387340 hasConcept C42360764 @default.
- W2022387340 hasConcept C9271920 @default.
- W2022387340 hasConceptScore W2022387340C127413603 @default.
- W2022387340 hasConceptScore W2022387340C155672457 @default.
- W2022387340 hasConceptScore W2022387340C171250308 @default.
- W2022387340 hasConceptScore W2022387340C192562407 @default.
- W2022387340 hasConceptScore W2022387340C2778123984 @default.
- W2022387340 hasConceptScore W2022387340C2779820397 @default.
- W2022387340 hasConceptScore W2022387340C2780165375 @default.
- W2022387340 hasConceptScore W2022387340C42360764 @default.
- W2022387340 hasConceptScore W2022387340C9271920 @default.
- W2022387340 hasLocation W20223873401 @default.
- W2022387340 hasLocation W20223873402 @default.
- W2022387340 hasOpenAccess W2022387340 @default.
- W2022387340 hasPrimaryLocation W20223873401 @default.
- W2022387340 hasRelatedWork W2439202765 @default.
- W2022387340 hasRelatedWork W2514957511 @default.
- W2022387340 hasRelatedWork W2838882379 @default.