FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022389660> ?p ?o ?g. }

• W2022389660 endingPage "126" @default.
• W2022389660 startingPage "119" @default.
• W2022389660 abstract "Background: The aim of this study was to evaluate the association of polymorphisms of the peroxisome proliferator-activated receptor gamma (PPARG) gene and peroxisome proliferators-activated receptor gamma co-activator 1 alpha (PPARGC1A) gene with diabetic nephropathy (DN) in Asian Indians. Methods: Six common polymorphisms, 3 of the PPARG gene [−1279G/A, Pro12Ala, and His478His (C/T)] and 3 of the PPARGC1A gene (Thr394Thr, Gly482Ser, and +A2962G) were studied in 571 normal glucose-tolerant (NGT) subjects, 255 type 2 diabetic (T2D) subjects without nephropathy, and 141 DN subjects. Genotypes were determined by polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP) and direct sequencing. Logistic regression analysis was performed to assess the covariables associated with DN. Results: Among the 6 polymorphisms examined, only the Gly482Ser of the PPARGC1A gene was significantly associated with DN. The genotype frequency of Ser/Ser genotype of the PPARGC1A gene was 8.8% (50/571) in NGT subjects, 7.8% (20/255) in T2D subjects, and 29.8% (42/141) in DN subjects. The odds ratios (ORs) for DN for the susceptible Gly/Ser and Ser/Ser genotype after adjusting for age, sex, body mass index, and duration of diabetes were 2.14 [95% confidence interval (CI), 1.23–3.72; P = 0.007] and 8.01 (95% CI, 3.89–16.47; P < 0.001), respectively. The unadjusted OR for DN for the XA genotype of the Thr394Thr polymorphism was 1.87 (95% CI, 1.20–2.92; P = 0.006) compared to T2D subjects. However, the significance was lost (P = 0.061) when adjusted for age, sex, BMI, and duration of diabetes. The +A2962G of PPARGC1A and the 3 polymorphisms of PPARG were not associated with DN. Conclusion: The Gly482Ser polymorphism of the PPARGC1A gene is associated with DN in Asian Indians." @default.
• W2022389660 created "2016-06-24" @default.
• W2022389660 creator A5034363861 @default.
• W2022389660 creator A5047095747 @default.
• W2022389660 creator A5071638736 @default.
• W2022389660 creator A5085831993 @default.
• W2022389660 date "2010-04-01" @default.
• W2022389660 modified "2023-10-16" @default.
• W2022389660 title "Association of the PPARGC1A Gene Polymorphism With Diabetic Nephropathy in an Asian Indian Population (CURES-41)" @default.
• W2022389660 cites W1963713924 @default.
• W2022389660 cites W1991595901 @default.
• W2022389660 cites W1996570221 @default.
• W2022389660 cites W2016761006 @default.
• W2022389660 cites W2023718792 @default.
• W2022389660 cites W2028285640 @default.
• W2022389660 cites W2045649324 @default.
• W2022389660 cites W2055943567 @default.
• W2022389660 cites W2075564716 @default.
• W2022389660 cites W2077464018 @default.
• W2022389660 cites W2081498154 @default.
• W2022389660 cites W2102552397 @default.
• W2022389660 cites W2104389054 @default.
• W2022389660 cites W2114098559 @default.
• W2022389660 cites W2123170094 @default.
• W2022389660 cites W2125357334 @default.
• W2022389660 cites W2134293572 @default.
• W2022389660 cites W2138289723 @default.
• W2022389660 cites W2138349742 @default.
• W2022389660 cites W2141789735 @default.
• W2022389660 cites W2147828134 @default.
• W2022389660 cites W2149524485 @default.
• W2022389660 cites W2154221186 @default.
• W2022389660 cites W2161840616 @default.
• W2022389660 cites W2171649770 @default.
• W2022389660 doi "https://doi.org/10.1089/met.2009.0040" @default.
• W2022389660 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19900151" @default.
• W2022389660 hasPublicationYear "2010" @default.
• W2022389660 type Work @default.
• W2022389660 sameAs 2022389660 @default.
• W2022389660 citedByCount "13" @default.
• W2022389660 countsByYear W20223896602012 @default.
• W2022389660 countsByYear W20223896602013 @default.
• W2022389660 countsByYear W20223896602014 @default.
• W2022389660 countsByYear W20223896602015 @default.
• W2022389660 countsByYear W20223896602017 @default.
• W2022389660 countsByYear W20223896602019 @default.
• W2022389660 countsByYear W20223896602020 @default.
• W2022389660 crossrefType "journal-article" @default.
• W2022389660 hasAuthorship W2022389660A5034363861 @default.
• W2022389660 hasAuthorship W2022389660A5047095747 @default.
• W2022389660 hasAuthorship W2022389660A5071638736 @default.
• W2022389660 hasAuthorship W2022389660A5085831993 @default.
• W2022389660 hasConcept C104317684 @default.
• W2022389660 hasConcept C12304452 @default.
• W2022389660 hasConcept C126322002 @default.
• W2022389660 hasConcept C130241916 @default.
• W2022389660 hasConcept C134018914 @default.
• W2022389660 hasConcept C135763542 @default.
• W2022389660 hasConcept C149737253 @default.
• W2022389660 hasConcept C156957248 @default.
• W2022389660 hasConcept C170493617 @default.
• W2022389660 hasConcept C187345961 @default.
• W2022389660 hasConcept C2777180221 @default.
• W2022389660 hasConcept C2779922275 @default.
• W2022389660 hasConcept C2908647359 @default.
• W2022389660 hasConcept C44249647 @default.
• W2022389660 hasConcept C54355233 @default.
• W2022389660 hasConcept C555293320 @default.
• W2022389660 hasConcept C71924100 @default.
• W2022389660 hasConcept C76252995 @default.
• W2022389660 hasConcept C77445288 @default.
• W2022389660 hasConcept C86339819 @default.
• W2022389660 hasConcept C86803240 @default.
• W2022389660 hasConcept C99454951 @default.
• W2022389660 hasConceptScore W2022389660C104317684 @default.
• W2022389660 hasConceptScore W2022389660C12304452 @default.
• W2022389660 hasConceptScore W2022389660C126322002 @default.
• W2022389660 hasConceptScore W2022389660C130241916 @default.
• W2022389660 hasConceptScore W2022389660C134018914 @default.
• W2022389660 hasConceptScore W2022389660C135763542 @default.
• W2022389660 hasConceptScore W2022389660C149737253 @default.
• W2022389660 hasConceptScore W2022389660C156957248 @default.
• W2022389660 hasConceptScore W2022389660C170493617 @default.
• W2022389660 hasConceptScore W2022389660C187345961 @default.
• W2022389660 hasConceptScore W2022389660C2777180221 @default.
• W2022389660 hasConceptScore W2022389660C2779922275 @default.
• W2022389660 hasConceptScore W2022389660C2908647359 @default.
• W2022389660 hasConceptScore W2022389660C44249647 @default.
• W2022389660 hasConceptScore W2022389660C54355233 @default.
• W2022389660 hasConceptScore W2022389660C555293320 @default.
• W2022389660 hasConceptScore W2022389660C71924100 @default.
• W2022389660 hasConceptScore W2022389660C76252995 @default.
• W2022389660 hasConceptScore W2022389660C77445288 @default.
• W2022389660 hasConceptScore W2022389660C86339819 @default.
• W2022389660 hasConceptScore W2022389660C86803240 @default.
• W2022389660 hasConceptScore W2022389660C99454951 @default.
• W2022389660 hasIssue "2" @default.
• W2022389660 hasLocation W20223896601 @default.

• next