Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022390473> ?p ?o ?g. }
- W2022390473 endingPage "2381" @default.
- W2022390473 startingPage "2368" @default.
- W2022390473 abstract "The interaction of anthracyclines (daunorubicin and idarubicin) with monolayers of zwitterionic palmitoyloleoylphosphatidylcholine (POPC) and anionic dipalmitoylphosphatidic acid (POPC-DPPA 80–20 mol%) was studied by surface pressure measurements and compared with previous results obtained with other anthracyclines (pirarubicin and adriamycin). These anthracycline/phospholipid monolayers were next transferred by a Langmuir-Blodgett technique onto planar supports and studied by surface-enhanced resonance Raman scattering (SERRS), which gave information about the orientation of anthracycline in the monolayers. On the whole, the adsorption of anthracyclines in zwitterionic monolayers increases with the anthracycline hydrophobic/hydrophilic balance, which underlines the role of the hydrophobic component of the interaction. On the contrary, the anthracyclines remain adsorbed on the polar headgroups of the phospholipids in the presence of DPPA and form a screen that limits a deeper penetration of other anthracycline molecules. To study by SERRS measurements the crossing of pirarubicin through a phospholipid bilayer used as a membrane model, asymmetrical POPC-DPPA/POPC or POPC/POPC-DPPA bilayers were transferred by the Langmuir-Schäfer method, thanks to a laboratory-built set-up, and put in contact with a pirarubicin aqueous solution. It has been shown that the presence of anionic DPPA in the first monolayer in contact with pirarubicin would limit its crossing. This limiting effet is not observed if the first monolayer is zwitterionic." @default.
- W2022390473 created "2016-06-24" @default.
- W2022390473 creator A5012854933 @default.
- W2022390473 creator A5043932912 @default.
- W2022390473 creator A5047106573 @default.
- W2022390473 creator A5069687433 @default.
- W2022390473 date "1998-11-01" @default.
- W2022390473 modified "2023-09-30" @default.
- W2022390473 title "Orientation of Anthracyclines in Lipid Monolayers and Planar Asymmetrical Bilayers: A Surface-Enhanced Resonance Raman Scattering Study" @default.
- W2022390473 cites W1503396222 @default.
- W2022390473 cites W1601474717 @default.
- W2022390473 cites W1606086259 @default.
- W2022390473 cites W1964202127 @default.
- W2022390473 cites W1965413124 @default.
- W2022390473 cites W1978700189 @default.
- W2022390473 cites W1979224525 @default.
- W2022390473 cites W1982231976 @default.
- W2022390473 cites W1982689015 @default.
- W2022390473 cites W1983962844 @default.
- W2022390473 cites W1997668676 @default.
- W2022390473 cites W1997808521 @default.
- W2022390473 cites W1998015375 @default.
- W2022390473 cites W2013142297 @default.
- W2022390473 cites W2017092338 @default.
- W2022390473 cites W2019703214 @default.
- W2022390473 cites W2022711149 @default.
- W2022390473 cites W2023275725 @default.
- W2022390473 cites W2029132956 @default.
- W2022390473 cites W2029782824 @default.
- W2022390473 cites W2030686317 @default.
- W2022390473 cites W2033547045 @default.
- W2022390473 cites W2036117763 @default.
- W2022390473 cites W2040816497 @default.
- W2022390473 cites W2044423157 @default.
- W2022390473 cites W2046814085 @default.
- W2022390473 cites W2050410538 @default.
- W2022390473 cites W2065790254 @default.
- W2022390473 cites W2083102892 @default.
- W2022390473 cites W2087246411 @default.
- W2022390473 cites W2090702582 @default.
- W2022390473 cites W2091226144 @default.
- W2022390473 cites W2094906575 @default.
- W2022390473 cites W2104013724 @default.
- W2022390473 cites W2167582912 @default.
- W2022390473 doi "https://doi.org/10.1016/s0006-3495(98)77681-7" @default.
- W2022390473 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1299911" @default.
- W2022390473 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9788932" @default.
- W2022390473 hasPublicationYear "1998" @default.
- W2022390473 type Work @default.
- W2022390473 sameAs 2022390473 @default.
- W2022390473 citedByCount "44" @default.
- W2022390473 countsByYear W20223904732012 @default.
- W2022390473 countsByYear W20223904732013 @default.
- W2022390473 countsByYear W20223904732014 @default.
- W2022390473 countsByYear W20223904732015 @default.
- W2022390473 countsByYear W20223904732016 @default.
- W2022390473 countsByYear W20223904732017 @default.
- W2022390473 countsByYear W20223904732020 @default.
- W2022390473 countsByYear W20223904732021 @default.
- W2022390473 countsByYear W20223904732022 @default.
- W2022390473 countsByYear W20223904732023 @default.
- W2022390473 crossrefType "journal-article" @default.
- W2022390473 hasAuthorship W2022390473A5012854933 @default.
- W2022390473 hasAuthorship W2022390473A5043932912 @default.
- W2022390473 hasAuthorship W2022390473A5047106573 @default.
- W2022390473 hasAuthorship W2022390473A5069687433 @default.
- W2022390473 hasBestOaLocation W20223904731 @default.
- W2022390473 hasConcept C120665830 @default.
- W2022390473 hasConcept C121332964 @default.
- W2022390473 hasConcept C169573571 @default.
- W2022390473 hasConcept C185592680 @default.
- W2022390473 hasConcept C192157962 @default.
- W2022390473 hasConcept C2780943371 @default.
- W2022390473 hasConcept C39944091 @default.
- W2022390473 hasConcept C40003534 @default.
- W2022390473 hasConcept C41625074 @default.
- W2022390473 hasConcept C55493867 @default.
- W2022390473 hasConcept C7070889 @default.
- W2022390473 hasConceptScore W2022390473C120665830 @default.
- W2022390473 hasConceptScore W2022390473C121332964 @default.
- W2022390473 hasConceptScore W2022390473C169573571 @default.
- W2022390473 hasConceptScore W2022390473C185592680 @default.
- W2022390473 hasConceptScore W2022390473C192157962 @default.
- W2022390473 hasConceptScore W2022390473C2780943371 @default.
- W2022390473 hasConceptScore W2022390473C39944091 @default.
- W2022390473 hasConceptScore W2022390473C40003534 @default.
- W2022390473 hasConceptScore W2022390473C41625074 @default.
- W2022390473 hasConceptScore W2022390473C55493867 @default.
- W2022390473 hasConceptScore W2022390473C7070889 @default.
- W2022390473 hasIssue "5" @default.
- W2022390473 hasLocation W20223904731 @default.
- W2022390473 hasLocation W20223904732 @default.
- W2022390473 hasLocation W20223904733 @default.
- W2022390473 hasLocation W20223904734 @default.
- W2022390473 hasOpenAccess W2022390473 @default.
- W2022390473 hasPrimaryLocation W20223904731 @default.
- W2022390473 hasRelatedWork W2002491608 @default.
- W2022390473 hasRelatedWork W2013093095 @default.