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- W2022399993 abstract "The influence of water content of furosemide in a direct compressible tablet formulation was studied in pilot plant production. Small variations in the water content of furosemide as determined by thermogravimetry was found to have a substantial influence on the compaction properties of the direct compressible formulation.A study of furosemide per se revealed that an increase in water content from 0.06% to 0.24% resulted in an increased elastic recovery and decreased net work at compaction. By adjusting the water content of furosemide in the direct compressible formulation it was possible to avoid the capping tendency at tablets." @default.
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- W2022399993 date "1989-01-01" @default.
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- W2022399993 title "Influence of substance properties on scaling up of tablet formulations" @default.
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- W2022399993 doi "https://doi.org/10.3109/03639048909043658" @default.
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