Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022407518> ?p ?o ?g. }
- W2022407518 endingPage "515" @default.
- W2022407518 startingPage "501" @default.
- W2022407518 abstract "Although monitoring serum vancomycin concentrations in clinical practice is commonplace, the data supporting this practice are meager. The rationale for monitoring these concentrations is to improve the effectiveness and/or reduce the toxicity of the drug. However, there are no data to suggest that monitoring serum vancomycin concentrations improves the effectiveness of therapy. In addition, despite many case reports of vancomycin-associated nephrotoxicity and ototoxicity, it is unclear whether this agent truly causes such conditions. Moreover, there is no evidence that adherence to specific ranges of vancomycin concentrations will preclude these events. Finally, vancomycin pharmacokinetics are sufficiently predictable that adequate serum drug concentrations can be obtained with dosing methods that take into account the patient's age, weight, and renal function. Safe and effective vancomycin dosage regimens can be constructed with these empirical dosing methods, whereas monitoring vancomycin levels increases the cost of therapy without improving the safety or efficacy of treatment." @default.
- W2022407518 created "2016-06-24" @default.
- W2022407518 creator A5027789378 @default.
- W2022407518 creator A5046470818 @default.
- W2022407518 creator A5083654602 @default.
- W2022407518 date "1994-04-01" @default.
- W2022407518 modified "2023-09-25" @default.
- W2022407518 title "Serum Vancomycin Concentrations: Reappraisal of Their Clinical Value" @default.
- W2022407518 cites W1495277525 @default.
- W2022407518 cites W1534257421 @default.
- W2022407518 cites W153823666 @default.
- W2022407518 cites W1835445007 @default.
- W2022407518 cites W1901078584 @default.
- W2022407518 cites W1964200136 @default.
- W2022407518 cites W1964250366 @default.
- W2022407518 cites W1964721019 @default.
- W2022407518 cites W1965306544 @default.
- W2022407518 cites W1965822140 @default.
- W2022407518 cites W1970368467 @default.
- W2022407518 cites W1974669554 @default.
- W2022407518 cites W1974824884 @default.
- W2022407518 cites W1975150477 @default.
- W2022407518 cites W1976860460 @default.
- W2022407518 cites W1981169980 @default.
- W2022407518 cites W1981375683 @default.
- W2022407518 cites W198333670 @default.
- W2022407518 cites W1985643390 @default.
- W2022407518 cites W1987742189 @default.
- W2022407518 cites W1988602517 @default.
- W2022407518 cites W1997260449 @default.
- W2022407518 cites W1998341324 @default.
- W2022407518 cites W1999116056 @default.
- W2022407518 cites W2001717618 @default.
- W2022407518 cites W2002550359 @default.
- W2022407518 cites W2002609036 @default.
- W2022407518 cites W2005523935 @default.
- W2022407518 cites W2008007630 @default.
- W2022407518 cites W2008942121 @default.
- W2022407518 cites W2010037180 @default.
- W2022407518 cites W2012442465 @default.
- W2022407518 cites W2016048303 @default.
- W2022407518 cites W2020306249 @default.
- W2022407518 cites W2022806706 @default.
- W2022407518 cites W2026025001 @default.
- W2022407518 cites W2029989962 @default.
- W2022407518 cites W2030160713 @default.
- W2022407518 cites W2030690572 @default.
- W2022407518 cites W2035496186 @default.
- W2022407518 cites W2036129782 @default.
- W2022407518 cites W2040119817 @default.
- W2022407518 cites W2044363049 @default.
- W2022407518 cites W2045417290 @default.
- W2022407518 cites W2045706513 @default.
- W2022407518 cites W2046215234 @default.
- W2022407518 cites W2051653823 @default.
- W2022407518 cites W2054150676 @default.
- W2022407518 cites W2057587497 @default.
- W2022407518 cites W2058341549 @default.
- W2022407518 cites W2061349669 @default.
- W2022407518 cites W2061877575 @default.
- W2022407518 cites W2062001308 @default.
- W2022407518 cites W2062870535 @default.
- W2022407518 cites W2065659219 @default.
- W2022407518 cites W2065798273 @default.
- W2022407518 cites W2065954473 @default.
- W2022407518 cites W2068381276 @default.
- W2022407518 cites W2068958668 @default.
- W2022407518 cites W2069998883 @default.
- W2022407518 cites W2070936203 @default.
- W2022407518 cites W2071924505 @default.
- W2022407518 cites W2074164991 @default.
- W2022407518 cites W2081236091 @default.
- W2022407518 cites W2083544037 @default.
- W2022407518 cites W2084817623 @default.
- W2022407518 cites W2086069144 @default.
- W2022407518 cites W2109268821 @default.
- W2022407518 cites W2110459621 @default.
- W2022407518 cites W2110588410 @default.
- W2022407518 cites W2114422486 @default.
- W2022407518 cites W2117318054 @default.
- W2022407518 cites W2125306607 @default.
- W2022407518 cites W2126520713 @default.
- W2022407518 cites W2126925117 @default.
- W2022407518 cites W2133975782 @default.
- W2022407518 cites W2138714556 @default.
- W2022407518 cites W2138768443 @default.
- W2022407518 cites W2142698632 @default.
- W2022407518 cites W2145556299 @default.
- W2022407518 cites W2155626541 @default.
- W2022407518 cites W2163456936 @default.
- W2022407518 cites W2167651673 @default.
- W2022407518 cites W2170481607 @default.
- W2022407518 cites W2315609346 @default.
- W2022407518 cites W2335548689 @default.
- W2022407518 cites W2336407133 @default.
- W2022407518 cites W2339419571 @default.
- W2022407518 cites W2394597768 @default.
- W2022407518 cites W2403976245 @default.