FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022485770> ?p ?o ?g. }

• W2022485770 endingPage "275" @default.
• W2022485770 startingPage "266" @default.
• W2022485770 abstract "Recurrence of hepatitis C virus (HCV) infection after liver transplantation is almost universal and usually leads to chronic hepatitis with different degrees of severity. The pathogenic mechanisms underlying the variable outcome of HCV infection recurrence are not well defined, but recent data suggest that the dynamics of HCV quasispecies may be involved. HCV quasispecies evolution was traced by longitudinal single strand conformation polymorphism, direct sequencing, and cloning analyses of pre- and post-transplant HCV-1b isolates from patients with histologically severe (seven cases) or mild or moderate (nine cases) HCV infection recurrence. Differences between the two groups of patients that concerned the level of viremia or the degree of HCV quasispecies complexity and diversity were not observed at any of the three time points analyzed. However, emergence of nucleotide and amino acid changes during the 12 months follow-up was significantly more frequent in patients with mild or moderate than in those with severe HCV infection recurrence. The ratio of non-synonymous to synonymous nucleotide substitutions 12 months after transplantation was also greater in the former, suggesting that the HVR1 of HCV is under stronger selective pressure in these subjects. These findings suggest that the degree of amino acid diversification in the HVR1 of HCV, which probably reflects the strength of immune pressure on HCV, is inversely related to the histological severity of HCV infection recurrence." @default.
• W2022485770 created "2016-06-24" @default.
• W2022485770 creator A5011258347 @default.
• W2022485770 creator A5027268186 @default.
• W2022485770 creator A5032017679 @default.
• W2022485770 creator A5033472322 @default.
• W2022485770 creator A5060724793 @default.
• W2022485770 creator A5079349599 @default.
• W2022485770 creator A5083988458 @default.
• W2022485770 date "2001-08-14" @default.
• W2022485770 modified "2023-10-18" @default.
• W2022485770 title "Influence of the dynamics of the hypervariable region 1 of hepatitis C virus (HCV) on the histological severity of HCV recurrence after liver transplantation" @default.
• W2022485770 cites W1598503360 @default.
• W2022485770 cites W1656291587 @default.
• W2022485770 cites W1673857160 @default.
• W2022485770 cites W1777263409 @default.
• W2022485770 cites W1871241548 @default.
• W2022485770 cites W1902746983 @default.
• W2022485770 cites W1964146549 @default.
• W2022485770 cites W1964335013 @default.
• W2022485770 cites W1974940736 @default.
• W2022485770 cites W1979003966 @default.
• W2022485770 cites W1982667986 @default.
• W2022485770 cites W1985379165 @default.
• W2022485770 cites W1987308001 @default.
• W2022485770 cites W1994771406 @default.
• W2022485770 cites W1999236476 @default.
• W2022485770 cites W1999996561 @default.
• W2022485770 cites W2000225550 @default.
• W2022485770 cites W2008662751 @default.
• W2022485770 cites W2009817284 @default.
• W2022485770 cites W2013620894 @default.
• W2022485770 cites W2017017909 @default.
• W2022485770 cites W2022291864 @default.
• W2022485770 cites W2024331982 @default.
• W2022485770 cites W2032126505 @default.
• W2022485770 cites W2044853267 @default.
• W2022485770 cites W2051962144 @default.
• W2022485770 cites W2054721877 @default.
• W2022485770 cites W2059677170 @default.
• W2022485770 cites W2086431635 @default.
• W2022485770 cites W2091624333 @default.
• W2022485770 cites W2102942916 @default.
• W2022485770 cites W2112251725 @default.
• W2022485770 cites W2113202023 @default.
• W2022485770 cites W2118440713 @default.
• W2022485770 cites W2122228848 @default.
• W2022485770 cites W2122679529 @default.
• W2022485770 cites W2128868625 @default.
• W2022485770 cites W2131692044 @default.
• W2022485770 cites W2137880935 @default.
• W2022485770 cites W2138967179 @default.
• W2022485770 cites W2148177756 @default.
• W2022485770 cites W2159954692 @default.
• W2022485770 cites W2161061337 @default.
• W2022485770 cites W2162552146 @default.
• W2022485770 cites W2166430610 @default.
• W2022485770 cites W2318197279 @default.
• W2022485770 doi "https://doi.org/10.1002/jmv.2029" @default.
• W2022485770 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11536232" @default.
• W2022485770 hasPublicationYear "2001" @default.
• W2022485770 type Work @default.
• W2022485770 sameAs 2022485770 @default.
• W2022485770 citedByCount "34" @default.
• W2022485770 countsByYear W20224857702012 @default.
• W2022485770 countsByYear W20224857702013 @default.
• W2022485770 countsByYear W20224857702014 @default.
• W2022485770 countsByYear W20224857702015 @default.
• W2022485770 countsByYear W20224857702019 @default.
• W2022485770 crossrefType "journal-article" @default.
• W2022485770 hasAuthorship W2022485770A5011258347 @default.
• W2022485770 hasAuthorship W2022485770A5027268186 @default.
• W2022485770 hasAuthorship W2022485770A5032017679 @default.
• W2022485770 hasAuthorship W2022485770A5033472322 @default.
• W2022485770 hasAuthorship W2022485770A5060724793 @default.
• W2022485770 hasAuthorship W2022485770A5079349599 @default.
• W2022485770 hasAuthorship W2022485770A5083988458 @default.
• W2022485770 hasConcept C126322002 @default.
• W2022485770 hasConcept C142462285 @default.
• W2022485770 hasConcept C14500911 @default.
• W2022485770 hasConcept C159047783 @default.
• W2022485770 hasConcept C159654299 @default.
• W2022485770 hasConcept C203014093 @default.
• W2022485770 hasConcept C2522874641 @default.
• W2022485770 hasConcept C2776185481 @default.
• W2022485770 hasConcept C2776408679 @default.
• W2022485770 hasConcept C2776455275 @default.
• W2022485770 hasConcept C2779609443 @default.
• W2022485770 hasConcept C2781463415 @default.
• W2022485770 hasConcept C2911091166 @default.
• W2022485770 hasConcept C3019392825 @default.
• W2022485770 hasConcept C71924100 @default.
• W2022485770 hasConcept C81566733 @default.
• W2022485770 hasConcept C86803240 @default.
• W2022485770 hasConcept C8891405 @default.
• W2022485770 hasConceptScore W2022485770C126322002 @default.
• W2022485770 hasConceptScore W2022485770C142462285 @default.
• W2022485770 hasConceptScore W2022485770C14500911 @default.

• next