Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022515102> ?p ?o ?g. }
- W2022515102 endingPage "337" @default.
- W2022515102 startingPage "329" @default.
- W2022515102 abstract "In a search for neurotrophic factors (NTFs) regulating retinal ganglion cell (RGC) death in the chick embryo we have used purified and cultured RGCs. Purification of RGCs from embryonic day 10 was achieved by employing the “panning” method (Silverstein and Chun: Soc Neurosci Abstr 13:1054, 1987). The obtained neuron population consisted of 97% RGCs as demonstrated by retrograde labeling with a fluorescence dye. RGCs were cultured at low density in a chemically defined medium and shortterm survival (24 hr) was determined. In the absence of NTFs, less than 3% of the RGCs survived. In the presence of various crude or purified NTFs (eye, brain, and tectum extracts; glial-conditioned medium; ciliary nerotrophic factor [CNTF]; nerve growth factor [NGF]) 31% to 52% of the RGCs were maintained. The effects of NGF and CNTF were not additive. Neither acidic nor basic fibroblast growth factor was able to maintain RGCs in culture. Our results, obtained with a culture system which allowed the analysis of direct trophic actions, suggest that NGF and CNTF may be NTFs for overlapping subpopulations of chick RGCs." @default.
- W2022515102 created "2016-06-24" @default.
- W2022515102 creator A5031772776 @default.
- W2022515102 creator A5047686228 @default.
- W2022515102 creator A5058290437 @default.
- W2022515102 date "1989-10-01" @default.
- W2022515102 modified "2023-09-26" @default.
- W2022515102 title "Survival of purified embryonic chick retinal ganglion cells in the presence of neurotrophic factors" @default.
- W2022515102 cites W1527035699 @default.
- W2022515102 cites W1570354531 @default.
- W2022515102 cites W1600830780 @default.
- W2022515102 cites W1677079502 @default.
- W2022515102 cites W1798397193 @default.
- W2022515102 cites W195049236 @default.
- W2022515102 cites W1952281904 @default.
- W2022515102 cites W1966194517 @default.
- W2022515102 cites W1971503445 @default.
- W2022515102 cites W1994365433 @default.
- W2022515102 cites W1995353620 @default.
- W2022515102 cites W2003149218 @default.
- W2022515102 cites W2003427180 @default.
- W2022515102 cites W2008530919 @default.
- W2022515102 cites W2009883048 @default.
- W2022515102 cites W2017130768 @default.
- W2022515102 cites W2017174460 @default.
- W2022515102 cites W2018405602 @default.
- W2022515102 cites W2021418176 @default.
- W2022515102 cites W2024205653 @default.
- W2022515102 cites W2032304720 @default.
- W2022515102 cites W2033775881 @default.
- W2022515102 cites W2033955043 @default.
- W2022515102 cites W2035376674 @default.
- W2022515102 cites W2036283349 @default.
- W2022515102 cites W2044758293 @default.
- W2022515102 cites W2044858838 @default.
- W2022515102 cites W2046456966 @default.
- W2022515102 cites W2049811908 @default.
- W2022515102 cites W2051417917 @default.
- W2022515102 cites W2052508016 @default.
- W2022515102 cites W2055164554 @default.
- W2022515102 cites W2058042895 @default.
- W2022515102 cites W2060183661 @default.
- W2022515102 cites W2060746536 @default.
- W2022515102 cites W2070649318 @default.
- W2022515102 cites W2071487260 @default.
- W2022515102 cites W2074472425 @default.
- W2022515102 cites W2074614649 @default.
- W2022515102 cites W2077384038 @default.
- W2022515102 cites W2078624314 @default.
- W2022515102 cites W2079826112 @default.
- W2022515102 cites W2083103068 @default.
- W2022515102 cites W2091912638 @default.
- W2022515102 cites W2099879877 @default.
- W2022515102 cites W2165609315 @default.
- W2022515102 cites W2338941502 @default.
- W2022515102 cites W2341889730 @default.
- W2022515102 cites W2476735357 @default.
- W2022515102 cites W4242634578 @default.
- W2022515102 cites W4293247451 @default.
- W2022515102 doi "https://doi.org/10.1002/jnr.490240225" @default.
- W2022515102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2585553" @default.
- W2022515102 hasPublicationYear "1989" @default.
- W2022515102 type Work @default.
- W2022515102 sameAs 2022515102 @default.
- W2022515102 citedByCount "70" @default.
- W2022515102 countsByYear W20225151022012 @default.
- W2022515102 countsByYear W20225151022014 @default.
- W2022515102 countsByYear W20225151022015 @default.
- W2022515102 crossrefType "journal-article" @default.
- W2022515102 hasAuthorship W2022515102A5031772776 @default.
- W2022515102 hasAuthorship W2022515102A5047686228 @default.
- W2022515102 hasAuthorship W2022515102A5058290437 @default.
- W2022515102 hasConcept C104317684 @default.
- W2022515102 hasConcept C105702510 @default.
- W2022515102 hasConcept C145103041 @default.
- W2022515102 hasConcept C153911025 @default.
- W2022515102 hasConcept C160539049 @default.
- W2022515102 hasConcept C169760540 @default.
- W2022515102 hasConcept C170493617 @default.
- W2022515102 hasConcept C2777093970 @default.
- W2022515102 hasConcept C2777624874 @default.
- W2022515102 hasConcept C2778423431 @default.
- W2022515102 hasConcept C2908647359 @default.
- W2022515102 hasConcept C55493867 @default.
- W2022515102 hasConcept C68710172 @default.
- W2022515102 hasConcept C71924100 @default.
- W2022515102 hasConcept C74373430 @default.
- W2022515102 hasConcept C86803240 @default.
- W2022515102 hasConcept C92020748 @default.
- W2022515102 hasConcept C95444343 @default.
- W2022515102 hasConcept C99454951 @default.
- W2022515102 hasConceptScore W2022515102C104317684 @default.
- W2022515102 hasConceptScore W2022515102C105702510 @default.
- W2022515102 hasConceptScore W2022515102C145103041 @default.
- W2022515102 hasConceptScore W2022515102C153911025 @default.
- W2022515102 hasConceptScore W2022515102C160539049 @default.
- W2022515102 hasConceptScore W2022515102C169760540 @default.
- W2022515102 hasConceptScore W2022515102C170493617 @default.