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• W2022515237 abstract "The aim of this study was to evaluate the composition of the subgingival microbiota of alcoholic and non-alcoholic individuals. The study was conducted with 49 alcoholic and 49 non-alcoholic males of the Philippe Pinel Institute, Rio de Janeiro, Brazil. The subjects were selected by convenience and two criteria were used to diagnose alcohol dependence: the CAGE (cut-down, annoyed, guilt, eyes-opener) questionnaire and the International Statistical Classification of Diseases, 10th edition (WHO). Subgingival biofilm samples were obtained from 4 sites, 2 with probing depth (PD) ≥ 4 mm and 2 sites with PD < 4 mm. The presence and levels of 45 bacterial taxa were analysed using the checkerboard technique. The prevalence of bacterial species was not significantly different between groups. However, alcoholics showed significantly higher mean counts of Aggregactibacter actinomycetemcomitans, Fusobacterium nucleatum nucleatum, and Porphyromonas gingivalis (adjusted p < 0.001). Moreover, alcoholics harboured significantly higher mean levels of Capnocytophaga sputigena, Fusobacterium nucleatum vincentii, F. nuc. nucleatum, Gemella morbillorum, Neisseria mucosa, P. gingivalis, Streptococcus gordonii, and Tannerella forsythia at sites with PD <4 mm or ≥4 mm compared to non-alcoholics (p ≤ 0.001). Of interest, shallow sites of alcoholics presented significantly higher mean levels of F. nuc. vincentii, F. nuc nucleatum, P. gingivalis, and T. forsythia than sites with PD ≥ 4 mm of non-alcoholics (p ≤ 0.001). Alcoholics and non-alcoholics present a diverse and complex microbiota; however, alcoholics harbour significantly higher levels of periodontopathic species in the subgingival microbiota than non-alcoholics." @default.
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• W2022515237 date "2011-11-01" @default.
• W2022515237 modified "2023-09-26" @default.
• W2022515237 title "Evaluation of the subgingival microbiota of alcoholic and non-alcoholic individuals" @default.
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• W2022515237 doi "https://doi.org/10.1016/j.jdent.2011.08.004" @default.
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