Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022515934> ?p ?o ?g. }
- W2022515934 endingPage "656" @default.
- W2022515934 startingPage "647" @default.
- W2022515934 abstract "Vibrio cholerae is the causative agent of the diarrheal disease cholera. By an incompletely understood developmental process, V. cholerae forms complex surface-associated communities called biofilms. Here we show that quorum sensing-deficient mutants of V. cholerae produce thicker biofilms than those formed by wild-type bacteria. Microarray analysis of biofilm-associated bacteria shows that expression of the Vibrio polysaccharide synthesis (vps) operons is enhanced in hapR mutants. CqsA, one of two known autoinducer synthases in V. cholerae, acts through HapR to repress vps gene expression. Vibrio biofilms are more acid resistant than planktonic cells. However, quorum sensing-deficient biofilms have lower colonization capacities than those of wild-type biofilms, suggesting that quorum sensing may promote cellular exit from the biofilm once the organisms have traversed the gastric acid barrier of the stomach. These results shed light on the relationships among biofilm development, quorum sensing, infectivity, and pathogenesis in V. cholerae." @default.
- W2022515934 created "2016-06-24" @default.
- W2022515934 creator A5032712567 @default.
- W2022515934 creator A5045253972 @default.
- W2022515934 date "2003-10-01" @default.
- W2022515934 modified "2023-10-04" @default.
- W2022515934 title "Quorum Sensing-Dependent Biofilms Enhance Colonization in Vibrio cholerae" @default.
- W2022515934 cites W1555657499 @default.
- W2022515934 cites W1598064331 @default.
- W2022515934 cites W1709049546 @default.
- W2022515934 cites W1787705516 @default.
- W2022515934 cites W1904615796 @default.
- W2022515934 cites W1908490865 @default.
- W2022515934 cites W1966742875 @default.
- W2022515934 cites W1969295342 @default.
- W2022515934 cites W1970057259 @default.
- W2022515934 cites W1992256609 @default.
- W2022515934 cites W1993405993 @default.
- W2022515934 cites W1996608975 @default.
- W2022515934 cites W2000106451 @default.
- W2022515934 cites W2016402044 @default.
- W2022515934 cites W2026966110 @default.
- W2022515934 cites W2029404175 @default.
- W2022515934 cites W2043015302 @default.
- W2022515934 cites W2050269111 @default.
- W2022515934 cites W2056932987 @default.
- W2022515934 cites W2079229636 @default.
- W2022515934 cites W2079698171 @default.
- W2022515934 cites W2090639003 @default.
- W2022515934 cites W2091123893 @default.
- W2022515934 cites W2093201831 @default.
- W2022515934 cites W2105173502 @default.
- W2022515934 cites W2107304641 @default.
- W2022515934 cites W2107757630 @default.
- W2022515934 cites W2108993526 @default.
- W2022515934 cites W2112988492 @default.
- W2022515934 cites W2114430992 @default.
- W2022515934 cites W2116771891 @default.
- W2022515934 cites W2117664645 @default.
- W2022515934 cites W2119357947 @default.
- W2022515934 cites W2126588228 @default.
- W2022515934 cites W2126922170 @default.
- W2022515934 cites W2130380516 @default.
- W2022515934 cites W2135110121 @default.
- W2022515934 cites W2144440398 @default.
- W2022515934 cites W2150747025 @default.
- W2022515934 cites W2160983200 @default.
- W2022515934 cites W2166421183 @default.
- W2022515934 cites W4253270129 @default.
- W2022515934 doi "https://doi.org/10.1016/s1534-5807(03)00295-8" @default.
- W2022515934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14536065" @default.
- W2022515934 hasPublicationYear "2003" @default.
- W2022515934 type Work @default.
- W2022515934 sameAs 2022515934 @default.
- W2022515934 citedByCount "492" @default.
- W2022515934 countsByYear W20225159342012 @default.
- W2022515934 countsByYear W20225159342013 @default.
- W2022515934 countsByYear W20225159342014 @default.
- W2022515934 countsByYear W20225159342015 @default.
- W2022515934 countsByYear W20225159342016 @default.
- W2022515934 countsByYear W20225159342017 @default.
- W2022515934 countsByYear W20225159342018 @default.
- W2022515934 countsByYear W20225159342019 @default.
- W2022515934 countsByYear W20225159342020 @default.
- W2022515934 countsByYear W20225159342021 @default.
- W2022515934 countsByYear W20225159342022 @default.
- W2022515934 countsByYear W20225159342023 @default.
- W2022515934 crossrefType "journal-article" @default.
- W2022515934 hasAuthorship W2022515934A5032712567 @default.
- W2022515934 hasAuthorship W2022515934A5045253972 @default.
- W2022515934 hasBestOaLocation W20225159341 @default.
- W2022515934 hasConcept C104317684 @default.
- W2022515934 hasConcept C118687296 @default.
- W2022515934 hasConcept C143065580 @default.
- W2022515934 hasConcept C2776927270 @default.
- W2022515934 hasConcept C2778643871 @default.
- W2022515934 hasConcept C523546767 @default.
- W2022515934 hasConcept C54355233 @default.
- W2022515934 hasConcept C58123911 @default.
- W2022515934 hasConcept C86803240 @default.
- W2022515934 hasConcept C89423630 @default.
- W2022515934 hasConcept C95282255 @default.
- W2022515934 hasConceptScore W2022515934C104317684 @default.
- W2022515934 hasConceptScore W2022515934C118687296 @default.
- W2022515934 hasConceptScore W2022515934C143065580 @default.
- W2022515934 hasConceptScore W2022515934C2776927270 @default.
- W2022515934 hasConceptScore W2022515934C2778643871 @default.
- W2022515934 hasConceptScore W2022515934C523546767 @default.
- W2022515934 hasConceptScore W2022515934C54355233 @default.
- W2022515934 hasConceptScore W2022515934C58123911 @default.
- W2022515934 hasConceptScore W2022515934C86803240 @default.
- W2022515934 hasConceptScore W2022515934C89423630 @default.
- W2022515934 hasConceptScore W2022515934C95282255 @default.
- W2022515934 hasFunder F4320311255 @default.
- W2022515934 hasFunder F4320332161 @default.
- W2022515934 hasIssue "4" @default.
- W2022515934 hasLocation W20225159341 @default.
- W2022515934 hasLocation W20225159342 @default.