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- W2022551497 abstract "In the present study, we demonstrated the differential role of spinal protein kinases in neuropathic and inflammatory pain. Mice with sciatic nerve ligation exhibited a spinal protein kinase C (PKC)-dependent neuropathic pain-like state. In contrast, an intraplanter injection of inflammatory agent caused a protein kinase A (PKA)-related thermal hyperalgesia. These findings suggest that the substantial activation of spinal PKC and PKA may differentially contribute to the development of respective chronic pain-like state in mice." @default.
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- W2022551497 date "2003-12-01" @default.
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- W2022551497 title "Differential involvement of spinal protein kinase C and protein kinase A in neuropathic and inflammatory pain in mice" @default.
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- W2022551497 doi "https://doi.org/10.1016/j.brainres.2003.08.042" @default.
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