Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022605758> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2022605758 endingPage "S109" @default.
- W2022605758 startingPage "S107" @default.
- W2022605758 abstract "Huntington's disease typically presents with involuntary movements, cognitive decline and behavioural abnormalities; however, new data show a greater spectrum and more complexity in the mode of presentation than previously appreciated. On one hand efforts are under way to better assess all aspects of the evolving phenotype over the course of the disease, on the other hand large cohorts have been prospectively followed-up and similar efforts are now being started in China. In this communication, we briefly review the most salient findings from the last couple of years. The recently established large cohorts allow the performance of accurate studies examining correlation of genetic polymorphisms with specific aspects of the phenotype thus allowing for some mechanistic insight into the causes of phenotypic variation. While Huntington's disease is the most frequent hereditary cause of chorea, other disorders with similar clinical phenotypes, including neuroacanthocytosis, are now better known, including a better understanding of the primary cause as well as the pathophysiology at the molecular level. Studies on the mechanisms of disease in these different disorders may shed light on the respective pathomechanisms and may open new approaches to a better understanding and additional treatment options for choreatiform neurodegenerative disorders." @default.
- W2022605758 created "2016-06-24" @default.
- W2022605758 creator A5021070522 @default.
- W2022605758 creator A5027287148 @default.
- W2022605758 creator A5084389843 @default.
- W2022605758 creator A5086704861 @default.
- W2022605758 date "2012-01-01" @default.
- W2022605758 modified "2023-10-16" @default.
- W2022605758 title "Huntington's disease: new aspects on phenotype and genotype" @default.
- W2022605758 cites W1594101812 @default.
- W2022605758 cites W1923182887 @default.
- W2022605758 cites W1968410057 @default.
- W2022605758 cites W1986317669 @default.
- W2022605758 cites W1987928566 @default.
- W2022605758 cites W1994473527 @default.
- W2022605758 cites W2031417185 @default.
- W2022605758 cites W2032844625 @default.
- W2022605758 cites W2047185643 @default.
- W2022605758 cites W2052378222 @default.
- W2022605758 cites W2080439721 @default.
- W2022605758 cites W2102653615 @default.
- W2022605758 cites W2123089799 @default.
- W2022605758 cites W2124660038 @default.
- W2022605758 cites W2129250133 @default.
- W2022605758 cites W2137414549 @default.
- W2022605758 cites W2152479582 @default.
- W2022605758 cites W2162229008 @default.
- W2022605758 doi "https://doi.org/10.1016/s1353-8020(11)70034-7" @default.
- W2022605758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22166403" @default.
- W2022605758 hasPublicationYear "2012" @default.
- W2022605758 type Work @default.
- W2022605758 sameAs 2022605758 @default.
- W2022605758 citedByCount "10" @default.
- W2022605758 countsByYear W20226057582013 @default.
- W2022605758 countsByYear W20226057582014 @default.
- W2022605758 countsByYear W20226057582015 @default.
- W2022605758 countsByYear W20226057582019 @default.
- W2022605758 countsByYear W20226057582022 @default.
- W2022605758 crossrefType "journal-article" @default.
- W2022605758 hasAuthorship W2022605758A5021070522 @default.
- W2022605758 hasAuthorship W2022605758A5027287148 @default.
- W2022605758 hasAuthorship W2022605758A5084389843 @default.
- W2022605758 hasAuthorship W2022605758A5086704861 @default.
- W2022605758 hasConcept C104317684 @default.
- W2022605758 hasConcept C127716648 @default.
- W2022605758 hasConcept C142724271 @default.
- W2022605758 hasConcept C169760540 @default.
- W2022605758 hasConcept C2778261627 @default.
- W2022605758 hasConcept C2778868616 @default.
- W2022605758 hasConcept C2779134260 @default.
- W2022605758 hasConcept C2780647506 @default.
- W2022605758 hasConcept C3020646490 @default.
- W2022605758 hasConcept C54355233 @default.
- W2022605758 hasConcept C60644358 @default.
- W2022605758 hasConcept C71924100 @default.
- W2022605758 hasConcept C86803240 @default.
- W2022605758 hasConceptScore W2022605758C104317684 @default.
- W2022605758 hasConceptScore W2022605758C127716648 @default.
- W2022605758 hasConceptScore W2022605758C142724271 @default.
- W2022605758 hasConceptScore W2022605758C169760540 @default.
- W2022605758 hasConceptScore W2022605758C2778261627 @default.
- W2022605758 hasConceptScore W2022605758C2778868616 @default.
- W2022605758 hasConceptScore W2022605758C2779134260 @default.
- W2022605758 hasConceptScore W2022605758C2780647506 @default.
- W2022605758 hasConceptScore W2022605758C3020646490 @default.
- W2022605758 hasConceptScore W2022605758C54355233 @default.
- W2022605758 hasConceptScore W2022605758C60644358 @default.
- W2022605758 hasConceptScore W2022605758C71924100 @default.
- W2022605758 hasConceptScore W2022605758C86803240 @default.
- W2022605758 hasLocation W20226057581 @default.
- W2022605758 hasLocation W20226057582 @default.
- W2022605758 hasOpenAccess W2022605758 @default.
- W2022605758 hasPrimaryLocation W20226057581 @default.
- W2022605758 hasRelatedWork W1988996344 @default.
- W2022605758 hasRelatedWork W1989544759 @default.
- W2022605758 hasRelatedWork W1999340858 @default.
- W2022605758 hasRelatedWork W2124916051 @default.
- W2022605758 hasRelatedWork W2150414946 @default.
- W2022605758 hasRelatedWork W2409705160 @default.
- W2022605758 hasRelatedWork W2413044502 @default.
- W2022605758 hasRelatedWork W2773353270 @default.
- W2022605758 hasRelatedWork W4244492395 @default.
- W2022605758 hasRelatedWork W4255658682 @default.
- W2022605758 hasVolume "18" @default.
- W2022605758 isParatext "false" @default.
- W2022605758 isRetracted "false" @default.
- W2022605758 magId "2022605758" @default.
- W2022605758 workType "article" @default.