Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022630113> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W2022630113 abstract "Time-resolved (TR) techniques have the potential to distinguish early- from late-arriving photons. Since light travelling through superficial tissue is detected earlier than photons that penetrate the deeper layers, time-windowing can in principle be used to improve the depth sensitivity of TR measurements. However, TR measurements also contain instrument contributions – referred to as the instrument-response-function (IRF) – which cause temporal broadening of the measured temporal-point-spread-function (TPSF). In this report, we investigate the influence of the IRF on pathlength-resolved absorption changes (Δμ<sub>a</sub>) retrieved from TR measurements using the microscopic Beer-Lambert law (MBLL). TPSFs were acquired on homogeneous and two-layer tissue-mimicking phantoms with varying optical properties. The measured IRF and TPSFs were deconvolved to recover the distribution of time-of-flights (DTOFs) of the detected photons. The microscopic Beer-Lambert law was applied to early and late time-windows of the TPSFs and DTOFs to access the effects of the IRF on pathlength-resolved Δμ<sub>a</sub>. The analysis showed that the late part of the TPSFs contains substantial contributions from early-arriving photons, due to the smearing effects of the IRF, which reduced its sensitivity to absorption changes occurring in deep layers. We also demonstrated that the effects of the IRF can be efficiently eliminated by applying a robust deconvolution technique, thereby improving the accuracy and sensitivity of TR measurements to deep-tissue absorption changes." @default.
- W2022630113 created "2016-06-24" @default.
- W2022630113 creator A5025550582 @default.
- W2022630113 creator A5072915154 @default.
- W2022630113 date "2013-03-25" @default.
- W2022630113 modified "2023-09-24" @default.
- W2022630113 title "Deconvolution improves the accuracy and depth sensitivity of time-resolved measurements" @default.
- W2022630113 cites W2007492138 @default.
- W2022630113 cites W2022527655 @default.
- W2022630113 cites W2090287453 @default.
- W2022630113 cites W2123644385 @default.
- W2022630113 cites W2147527166 @default.
- W2022630113 doi "https://doi.org/10.1117/12.2004850" @default.
- W2022630113 hasPublicationYear "2013" @default.
- W2022630113 type Work @default.
- W2022630113 sameAs 2022630113 @default.
- W2022630113 citedByCount "1" @default.
- W2022630113 countsByYear W20226301132023 @default.
- W2022630113 crossrefType "proceedings-article" @default.
- W2022630113 hasAuthorship W2022630113A5025550582 @default.
- W2022630113 hasAuthorship W2022630113A5072915154 @default.
- W2022630113 hasConcept C120665830 @default.
- W2022630113 hasConcept C121332964 @default.
- W2022630113 hasConcept C125287762 @default.
- W2022630113 hasConcept C127413603 @default.
- W2022630113 hasConcept C159317903 @default.
- W2022630113 hasConcept C174576160 @default.
- W2022630113 hasConcept C192562407 @default.
- W2022630113 hasConcept C21200559 @default.
- W2022630113 hasConcept C24326235 @default.
- W2022630113 hasConcept C2781402376 @default.
- W2022630113 hasConcept C69179731 @default.
- W2022630113 hasConceptScore W2022630113C120665830 @default.
- W2022630113 hasConceptScore W2022630113C121332964 @default.
- W2022630113 hasConceptScore W2022630113C125287762 @default.
- W2022630113 hasConceptScore W2022630113C127413603 @default.
- W2022630113 hasConceptScore W2022630113C159317903 @default.
- W2022630113 hasConceptScore W2022630113C174576160 @default.
- W2022630113 hasConceptScore W2022630113C192562407 @default.
- W2022630113 hasConceptScore W2022630113C21200559 @default.
- W2022630113 hasConceptScore W2022630113C24326235 @default.
- W2022630113 hasConceptScore W2022630113C2781402376 @default.
- W2022630113 hasConceptScore W2022630113C69179731 @default.
- W2022630113 hasLocation W20226301131 @default.
- W2022630113 hasOpenAccess W2022630113 @default.
- W2022630113 hasPrimaryLocation W20226301131 @default.
- W2022630113 hasRelatedWork W1966058083 @default.
- W2022630113 hasRelatedWork W1974256733 @default.
- W2022630113 hasRelatedWork W2036562164 @default.
- W2022630113 hasRelatedWork W2054367513 @default.
- W2022630113 hasRelatedWork W2116062465 @default.
- W2022630113 hasRelatedWork W2145401778 @default.
- W2022630113 hasRelatedWork W2767495796 @default.
- W2022630113 hasRelatedWork W2772088921 @default.
- W2022630113 hasRelatedWork W2801910480 @default.
- W2022630113 hasRelatedWork W3173543327 @default.
- W2022630113 isParatext "false" @default.
- W2022630113 isRetracted "false" @default.
- W2022630113 magId "2022630113" @default.
- W2022630113 workType "article" @default.