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• W2022641120 abstract "Background Pulmonary vein (PV) isolation is a technically challenging intervention. For this reason, integration of three-dimensional imaging with computed tomography (CT) or magnetic resonance imaging (MRI) in order to enhance effectiveness and safety has been widely adopted. A novel imaging approach—intraprocedural rotational angiography and reconstruction of the left atrium and PVs—is feasible and provides high anatomic accuracy. Objective The purpose of this study was to prove the feasibility, safety, and efficacy of this imaging approach as a single navigation tool for PV isolation. Methods Forty-four patients (25 men and 19 women; age 57 ± 11 years) with atrial fibrillation (AF) who presented for PV isolation were studied. Rotational angiography during adenosine-induced ventricular asystole was performed under sedation with propofol. The left atrium and PVs were reconstructed by three-dimensional atriography using specialized software (EP navigator prototype, Philips Medical Systems). Three-dimensional atriography was used as a single navigation tool for guiding PV isolation. Results Of 176 PVs, 174 (99%) were isolated. Total procedural and fluoroscopy times were 192 ± 46 minutes and 44 ± 12 minutes, respectively. During follow-up of 6 ± 3 months, 31 (70%) patients were free of symptoms and had no evidence of AF without any antiarrhythmic medication. MRI examination of 41 patients at 3-month follow-up excluded PV stenosis. No major complications occurred. Conclusion Three-dimensional atriography is a novel intraprocedural three-dimensional imaging technique that is based on rotational angiography. It can be safely and effectively used as a single navigation tool for performing PV isolation. Pulmonary vein (PV) isolation is a technically challenging intervention. For this reason, integration of three-dimensional imaging with computed tomography (CT) or magnetic resonance imaging (MRI) in order to enhance effectiveness and safety has been widely adopted. A novel imaging approach—intraprocedural rotational angiography and reconstruction of the left atrium and PVs—is feasible and provides high anatomic accuracy. The purpose of this study was to prove the feasibility, safety, and efficacy of this imaging approach as a single navigation tool for PV isolation. Forty-four patients (25 men and 19 women; age 57 ± 11 years) with atrial fibrillation (AF) who presented for PV isolation were studied. Rotational angiography during adenosine-induced ventricular asystole was performed under sedation with propofol. The left atrium and PVs were reconstructed by three-dimensional atriography using specialized software (EP navigator prototype, Philips Medical Systems). Three-dimensional atriography was used as a single navigation tool for guiding PV isolation. Of 176 PVs, 174 (99%) were isolated. Total procedural and fluoroscopy times were 192 ± 46 minutes and 44 ± 12 minutes, respectively. During follow-up of 6 ± 3 months, 31 (70%) patients were free of symptoms and had no evidence of AF without any antiarrhythmic medication. MRI examination of 41 patients at 3-month follow-up excluded PV stenosis. No major complications occurred. Three-dimensional atriography is a novel intraprocedural three-dimensional imaging technique that is based on rotational angiography. It can be safely and effectively used as a single navigation tool for performing PV isolation." @default.
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• W2022641120 date "2009-06-01" @default.
• W2022641120 modified "2023-09-26" @default.
• W2022641120 title "Intraprocedural reconstruction of the left atrium and pulmonary veins as a single navigation tool for ablation of atrial fibrillation: A feasibility, efficacy, and safety study" @default.
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• W2022641120 doi "https://doi.org/10.1016/j.hrthm.2009.02.037" @default.
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