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- W2022644639 abstract "Parasite sequestration at microvascular sites is a fundamental phenomenon in the manifestation of the symptoms of malaria and the progression to severe disease. Here, we review the endothelial cell-expressed intercellular adhesion molecule-1 (ICAM-1) and its role in mediating the interaction between the parasitised red blood cell (PRBC) and the vascular endothelium. We highlight the nature of the interaction between ICAM-1 and the parasite-expressed PfEMP-1 molecule at the molecular level. The review also discusses the complexity of the PRBC–endothelial cell interaction and the mechanisms that underlie parasite cytoadherence." @default.
- W2022644639 created "2016-06-24" @default.
- W2022644639 creator A5023260739 @default.
- W2022644639 creator A5091293033 @default.
- W2022644639 date "2005-01-01" @default.
- W2022644639 modified "2023-09-30" @default.
- W2022644639 title "The role of ICAM-1 in Plasmodium falciparum cytoadherence" @default.
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- W2022644639 doi "https://doi.org/10.1016/j.ejcb.2004.09.002" @default.
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