FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022645492> ?p ?o ?g. }

• W2022645492 endingPage "640" @default.
• W2022645492 startingPage "634" @default.
• W2022645492 abstract "In order to investigate the correlation among cytokine production and antiretroviral therapy (ART), viral load, CD4(+) and CD8(+) T lymphocytes, 55 human immunodeficiency virus (HIV)-1-infected children on ART or not, and 16 uninfected controls were studied. Peripheral blood mononuclear cells (PBMCs) of HIV-1-infected children and controls were cultured and spontaneous and mitogen-stimulated cytokines production was quantified in the supernatants. Viral load was quantified using standard molecular assay. CD4 and CD8 T-lymphocyte counts were determined by flow cytometry. Cytokine production by mitogen-stimulated PBMCs showed different profiles in HIV-1 children whether treated or not. The tumour necrosis factor (TNF)-alpha production was higher and the interleukin (IL)-10 production was lower in the HIV-1-untreated group than in the HIV-1-treated children and controls. The IL-2 production was reduced and the RANTES production was higher in both HIV-1 groups compared with the controls. The interferon (IFN)-gamma and the IL-5 production was significantly reduced in the HIV-1-treated children compared to the controls. Interestingly, the analysis of the correlation of HIV-1 phenotype with cytokine production indicated an increased RANTES production in relation to nonsyncytium-inducing viral phenotype with slow/low replication profile, whereas decreased IL-10 levels was associated to syncytium-inducing (SI) strains and rapid/high replication. Our findings suggest that AVT changes on the cytokine and chemokine production play an important role in the HIV pathogenesis." @default.
• W2022645492 created "2016-06-24" @default.
• W2022645492 creator A5014766542 @default.
• W2022645492 creator A5032023779 @default.
• W2022645492 creator A5075100851 @default.
• W2022645492 creator A5077220786 @default.
• W2022645492 creator A5091504998 @default.
• W2022645492 date "2000-12-01" @default.
• W2022645492 modified "2023-10-18" @default.
• W2022645492 title "Clinical Relevance of Cytokine Production in HIV-1 Infection in Children on Antiretroviral Therapy" @default.
• W2022645492 cites W1664573657 @default.
• W2022645492 cites W1964679138 @default.
• W2022645492 cites W1977665434 @default.
• W2022645492 cites W1990558754 @default.
• W2022645492 cites W1990677029 @default.
• W2022645492 cites W1993591984 @default.
• W2022645492 cites W2001679422 @default.
• W2022645492 cites W2002160929 @default.
• W2022645492 cites W2003847492 @default.
• W2022645492 cites W2005177157 @default.
• W2022645492 cites W2021460967 @default.
• W2022645492 cites W2037005014 @default.
• W2022645492 cites W2040868302 @default.
• W2022645492 cites W2041709827 @default.
• W2022645492 cites W2047905219 @default.
• W2022645492 cites W2050198252 @default.
• W2022645492 cites W2055853328 @default.
• W2022645492 cites W2060308187 @default.
• W2022645492 cites W2060546545 @default.
• W2022645492 cites W2069241748 @default.
• W2022645492 cites W2079341358 @default.
• W2022645492 cites W2082737563 @default.
• W2022645492 cites W2087884082 @default.
• W2022645492 cites W2092841597 @default.
• W2022645492 cites W2094174707 @default.
• W2022645492 cites W2138901765 @default.
• W2022645492 cites W2141608261 @default.
• W2022645492 cites W2170206314 @default.
• W2022645492 cites W2335496717 @default.
• W2022645492 cites W2338548517 @default.
• W2022645492 cites W2623542670 @default.
• W2022645492 cites W4247904595 @default.
• W2022645492 cites W4248746577 @default.
• W2022645492 doi "https://doi.org/10.1046/j.1365-3083.2000.00831.x" @default.
• W2022645492 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11119271" @default.
• W2022645492 hasPublicationYear "2000" @default.
• W2022645492 type Work @default.
• W2022645492 sameAs 2022645492 @default.
• W2022645492 citedByCount "12" @default.
• W2022645492 countsByYear W20226454922012 @default.
• W2022645492 countsByYear W20226454922014 @default.
• W2022645492 countsByYear W20226454922015 @default.
• W2022645492 countsByYear W20226454922017 @default.
• W2022645492 countsByYear W20226454922019 @default.
• W2022645492 crossrefType "journal-article" @default.
• W2022645492 hasAuthorship W2022645492A5014766542 @default.
• W2022645492 hasAuthorship W2022645492A5032023779 @default.
• W2022645492 hasAuthorship W2022645492A5075100851 @default.
• W2022645492 hasAuthorship W2022645492A5077220786 @default.
• W2022645492 hasAuthorship W2022645492A5091504998 @default.
• W2022645492 hasConcept C13373296 @default.
• W2022645492 hasConcept C137061746 @default.
• W2022645492 hasConcept C140704245 @default.
• W2022645492 hasConcept C142462285 @default.
• W2022645492 hasConcept C159047783 @default.
• W2022645492 hasConcept C167672396 @default.
• W2022645492 hasConcept C17991360 @default.
• W2022645492 hasConcept C202751555 @default.
• W2022645492 hasConcept C203014093 @default.
• W2022645492 hasConcept C2522874641 @default.
• W2022645492 hasConcept C2778690821 @default.
• W2022645492 hasConcept C2780942790 @default.
• W2022645492 hasConcept C55493867 @default.
• W2022645492 hasConcept C86803240 @default.
• W2022645492 hasConcept C8891405 @default.
• W2022645492 hasConceptScore W2022645492C13373296 @default.
• W2022645492 hasConceptScore W2022645492C137061746 @default.
• W2022645492 hasConceptScore W2022645492C140704245 @default.
• W2022645492 hasConceptScore W2022645492C142462285 @default.
• W2022645492 hasConceptScore W2022645492C159047783 @default.
• W2022645492 hasConceptScore W2022645492C167672396 @default.
• W2022645492 hasConceptScore W2022645492C17991360 @default.
• W2022645492 hasConceptScore W2022645492C202751555 @default.
• W2022645492 hasConceptScore W2022645492C203014093 @default.
• W2022645492 hasConceptScore W2022645492C2522874641 @default.
• W2022645492 hasConceptScore W2022645492C2778690821 @default.
• W2022645492 hasConceptScore W2022645492C2780942790 @default.
• W2022645492 hasConceptScore W2022645492C55493867 @default.
• W2022645492 hasConceptScore W2022645492C86803240 @default.
• W2022645492 hasConceptScore W2022645492C8891405 @default.
• W2022645492 hasIssue "6" @default.
• W2022645492 hasLocation W20226454921 @default.
• W2022645492 hasLocation W20226454922 @default.
• W2022645492 hasOpenAccess W2022645492 @default.
• W2022645492 hasPrimaryLocation W20226454921 @default.
• W2022645492 hasRelatedWork W1568848974 @default.
• W2022645492 hasRelatedWork W2085322992 @default.
• W2022645492 hasRelatedWork W2087976276 @default.

• next