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- W2022647351 abstract "The dose dependence on the intra-tumoral Mg concentration for the development of radiation-induced apoptosis was tested in vivo in Sarcoma-180 in BALB/c mice. The frequency of apoptosis was calculated as the number of apoptotic bodies per 100 nuclei by assaying with microscopic examination of H&E stain at 400× magnification. The Mg concentration was measured by means of particle induced X-ray emission (PIXE) at 3, 6, 12 and 24 h after 10 or 20 Gy 6 MeV electron irradiation of two groups of mice with and without oral administration of 0.1 mmol MgCl2 solution. There was a strong dose dependence on intra-tumoral Mg concentration for developing radiation-induced apoptosis (r = 0.78–0.89). The frequency of apoptosis was increased by oral administration of MgCl2. There was the possibility of radio-sensitization by facilitating the radiation-induced apoptosis by oral Mg administration." @default.
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- W2022647351 date "1996-04-01" @default.
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- W2022647351 title "Apoptosis and the trace elements" @default.
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