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- W2022653559 abstract "The upper genital tract of women contains functional LH/human chorionic gonadotropin (hCG) receptors. Whether the cervix, an anatomical continuum of the uterus and fallopian tubes, also contains these receptors has never been investigated. Multiple receptor detection techniques revealed their presence with higher levels in endocervix than in ectocervix. The receptor positive cells include stratified squamous luminal epithelium of the ectocervix, columnar epithelium, glands, blood vessels, and smooth muscle in the endocervix. Treatment of cervical tissue minces with hCG resulted in a significant increase in cAMP levels and a decrease in cyclooxygenase-2 protein levels in endocervix, but not in ectocervix. In summary, human cervix contains functional LH/hCG receptors, which suggests that LH during the menstrual cycle and hCG during pregnancy may regulate cervical functions." @default.
- W2022653559 created "2016-06-24" @default.
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- W2022653559 date "2003-07-01" @default.
- W2022653559 modified "2023-10-14" @default.
- W2022653559 title "Human Cervix Contains Functional Luteinizing Hormone/Human Chorionic Gonadotropin Receptors" @default.
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- W2022653559 doi "https://doi.org/10.1210/jc.2002-021966" @default.
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