Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022653808> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2022653808 endingPage "991" @default.
- W2022653808 startingPage "983" @default.
- W2022653808 abstract "Purpose Low-dose-rate interstitial brachytherapy (LDRIB) represents an effective modality for treatment of oropharyngeal carcinoma. The drawback is radioexposure of medical personnel. To eliminate this concern, we initiated high-dose-rate interstitial brachytherapy (HDRIB) in 1993. The present study evaluated the efficacy and complications associated with this approach. Methods and materials Between 1993 and 2003, HDRIB ± external radiotherapy was used to treat 83 oropharyngeal squamous cell carcinomas. Median duration of follow-up was 26 months (range, 1–108 months). Of the 82 patients, 76 were previously untreated and 6 displayed previous history of head and neck cancer. T distribution comprised T1 (n = 7), T2 (n = 47), T3 (n = 24), and T4a (n = 5). External radiotherapy of 46 Gy was combined with 21 Gy/3.5 fractions/2 days HDRIB for 68 lesions, and 48 Gy/8 fractions/5 days HDRIB alone was used for 15 lesions. Involved nodes were either boosted by external radiotherapy or resected. Results Five-year local control, regional control, cause-specific and overall survival rates were 82%, 84%, 88%, and 64%, respectively. Local control rates for early (T1/T2) and advanced (T3/T4) tumors were 89% and 66%, respectively (p = 0.02). Transient soft tissue necrosis was experienced in 29% of patients. No bone sequelae were observed in previously untreated patients. Conclusions High-dose-rate interstitial brachytherapy could achieve excellent local control and acceptable rates of complication, equivalent to reported results for LDRIB series. Given the advantage of radioprotection, HDRIB may replace LDRIB in the treatment of oropharyngeal carcinoma." @default.
- W2022653808 created "2016-06-24" @default.
- W2022653808 creator A5024386298 @default.
- W2022653808 creator A5036525621 @default.
- W2022653808 creator A5059258258 @default.
- W2022653808 date "2004-07-01" @default.
- W2022653808 modified "2023-09-25" @default.
- W2022653808 title "High-dose-rate interstitial brachytherapy for oropharyngeal carcinoma: results of 83 lesions in 82 patients" @default.
- W2022653808 cites W1917157825 @default.
- W2022653808 cites W1966183433 @default.
- W2022653808 cites W2042834206 @default.
- W2022653808 cites W2065942846 @default.
- W2022653808 cites W2070899064 @default.
- W2022653808 cites W2080922686 @default.
- W2022653808 cites W2101718780 @default.
- W2022653808 cites W2102940690 @default.
- W2022653808 cites W2109398754 @default.
- W2022653808 cites W2121979933 @default.
- W2022653808 cites W2126367968 @default.
- W2022653808 cites W2149910644 @default.
- W2022653808 cites W2167050704 @default.
- W2022653808 cites W2171583583 @default.
- W2022653808 cites W2329538113 @default.
- W2022653808 cites W4293241248 @default.
- W2022653808 doi "https://doi.org/10.1016/j.ijrobp.2003.12.015" @default.
- W2022653808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15234031" @default.
- W2022653808 hasPublicationYear "2004" @default.
- W2022653808 type Work @default.
- W2022653808 sameAs 2022653808 @default.
- W2022653808 citedByCount "35" @default.
- W2022653808 countsByYear W20226538082013 @default.
- W2022653808 countsByYear W20226538082014 @default.
- W2022653808 countsByYear W20226538082016 @default.
- W2022653808 countsByYear W20226538082017 @default.
- W2022653808 countsByYear W20226538082018 @default.
- W2022653808 countsByYear W20226538082020 @default.
- W2022653808 countsByYear W20226538082021 @default.
- W2022653808 countsByYear W20226538082023 @default.
- W2022653808 crossrefType "journal-article" @default.
- W2022653808 hasAuthorship W2022653808A5024386298 @default.
- W2022653808 hasAuthorship W2022653808A5036525621 @default.
- W2022653808 hasAuthorship W2022653808A5059258258 @default.
- W2022653808 hasConcept C126322002 @default.
- W2022653808 hasConcept C126838900 @default.
- W2022653808 hasConcept C2777416452 @default.
- W2022653808 hasConcept C2777546739 @default.
- W2022653808 hasConcept C2989005 @default.
- W2022653808 hasConcept C3019992690 @default.
- W2022653808 hasConcept C509974204 @default.
- W2022653808 hasConcept C71924100 @default.
- W2022653808 hasConceptScore W2022653808C126322002 @default.
- W2022653808 hasConceptScore W2022653808C126838900 @default.
- W2022653808 hasConceptScore W2022653808C2777416452 @default.
- W2022653808 hasConceptScore W2022653808C2777546739 @default.
- W2022653808 hasConceptScore W2022653808C2989005 @default.
- W2022653808 hasConceptScore W2022653808C3019992690 @default.
- W2022653808 hasConceptScore W2022653808C509974204 @default.
- W2022653808 hasConceptScore W2022653808C71924100 @default.
- W2022653808 hasIssue "4" @default.
- W2022653808 hasLocation W20226538081 @default.
- W2022653808 hasLocation W20226538082 @default.
- W2022653808 hasOpenAccess W2022653808 @default.
- W2022653808 hasPrimaryLocation W20226538081 @default.
- W2022653808 hasRelatedWork W1852759094 @default.
- W2022653808 hasRelatedWork W1994865959 @default.
- W2022653808 hasRelatedWork W2126158017 @default.
- W2022653808 hasRelatedWork W2336847010 @default.
- W2022653808 hasRelatedWork W2384708512 @default.
- W2022653808 hasRelatedWork W2528568805 @default.
- W2022653808 hasRelatedWork W3120903604 @default.
- W2022653808 hasRelatedWork W4206581437 @default.
- W2022653808 hasRelatedWork W4220908969 @default.
- W2022653808 hasRelatedWork W4243514755 @default.
- W2022653808 hasVolume "59" @default.
- W2022653808 isParatext "false" @default.
- W2022653808 isRetracted "false" @default.
- W2022653808 magId "2022653808" @default.
- W2022653808 workType "article" @default.