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- W2022662912 abstract "In order to obtain sufficient quantities of pure populations of cells or a single cell from surrounding tissue for analytical investigation, we have developed an ultrasonic microdissection system. The system utilizes a vision-based method for detecting the contact between the microdissection needle tip and a target surface. A multilayer stack piezoelectric actuator is employed to generate ultrasonic vibrations for histological isolation. Automated micro-dissection is also realized using visual feedback and vision-based control. Experimental results on tumor tissue sections show that the system has a high dissection accuracy and efficiency and is able to realize dissecting arbitrary shapes in specified locations on a tissue sample. Furthermore, effects in variations of vibration amplitude and frequency of ultrasonic micro-dissection as well as needle insertion depths on micro-dissection accuracy and speed were evaluated." @default.
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- W2022662912 date "2014-04-10" @default.
- W2022662912 modified "2023-09-23" @default.
- W2022662912 title "Controlled ultrasonic micro-dissection of thin tissue sections" @default.
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- W2022662912 doi "https://doi.org/10.1007/s10544-014-9859-z" @default.
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