FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022668299> ?p ?o ?g. }

• W2022668299 endingPage "29" @default.
• W2022668299 startingPage "22" @default.
• W2022668299 abstract "Magnetic Resonance imaging (MR imaging) as a powerful non-invasive modality is of high global interest for early cancer detection. The aim of this study was the synthesis of nanodendrimer and its conjugate with monoclonal antibody C595 against breast cancer cell, followed by its chelating with gadolinium for its magnetic property. First, anti-MUC-1 monoclonal antibody C595 was coupled to a biodegradable biocompatible Anionic Linear Globular Dendrimer G2 (having polyethylene glycol core and citric acid shell). Then prepared nanocomplex loaded by gadolinium to make novel agent of functional MR imaging. Anticancer effects and MR imaging parameters of the prepared nanoconjugate was investigated under in vitro conditions doing performing several studies such as evaluation of monoclonal antibody C595 binding to mucine-1 (MUC-1) cell, its purification, size of nanoconjugate and relaxivity measurements. The obtained data showed a powerful relaxations as well as selective MUC-1 antigen binding to the cell. Based on the findings from the present research Gd3+-ALGDG2-C595 nano-probe may be a potential breast molecular imaging and therapeutic agent. However, further investigations by in vivo studies and clinical trials are in the pipeline." @default.
• W2022668299 created "2016-06-24" @default.
• W2022668299 creator A5018595109 @default.
• W2022668299 creator A5021179152 @default.
• W2022668299 creator A5071341985 @default.
• W2022668299 date "2013-01-01" @default.
• W2022668299 modified "2023-10-17" @default.
• W2022668299 title "Synthesis and Development of Gd&lt;sup&gt;3+&lt;/sup&gt;-ALGDG&lt;sub&gt;2&lt;/sub&gt;-C595 as MR Imaging Contrast Agent" @default.
• W2022668299 cites W1970590134 @default.
• W2022668299 cites W1975581446 @default.
• W2022668299 cites W1977075517 @default.
• W2022668299 cites W1977303945 @default.
• W2022668299 cites W1985430563 @default.
• W2022668299 cites W2003238045 @default.
• W2022668299 cites W2003836708 @default.
• W2022668299 cites W2025483883 @default.
• W2022668299 cites W2026370914 @default.
• W2022668299 cites W2056064623 @default.
• W2022668299 cites W2058414466 @default.
• W2022668299 cites W2060925585 @default.
• W2022668299 cites W2072928113 @default.
• W2022668299 cites W2088156602 @default.
• W2022668299 cites W2089944696 @default.
• W2022668299 cites W2127225450 @default.
• W2022668299 cites W2151153432 @default.
• W2022668299 cites W4232534952 @default.
• W2022668299 doi "https://doi.org/10.4236/jbnb.2013.41004" @default.
• W2022668299 hasPublicationYear "2013" @default.
• W2022668299 type Work @default.
• W2022668299 sameAs 2022668299 @default.
• W2022668299 citedByCount "4" @default.
• W2022668299 countsByYear W20226682992014 @default.
• W2022668299 countsByYear W20226682992015 @default.
• W2022668299 countsByYear W20226682992016 @default.
• W2022668299 countsByYear W20226682992019 @default.
• W2022668299 crossrefType "journal-article" @default.
• W2022668299 hasAuthorship W2022668299A5018595109 @default.
• W2022668299 hasAuthorship W2022668299A5021179152 @default.
• W2022668299 hasAuthorship W2022668299A5071341985 @default.
• W2022668299 hasBestOaLocation W20226682991 @default.
• W2022668299 hasConcept C12554922 @default.
• W2022668299 hasConcept C126838900 @default.
• W2022668299 hasConcept C134306372 @default.
• W2022668299 hasConcept C143409427 @default.
• W2022668299 hasConcept C150903083 @default.
• W2022668299 hasConcept C159654299 @default.
• W2022668299 hasConcept C178790620 @default.
• W2022668299 hasConcept C185592680 @default.
• W2022668299 hasConcept C192562407 @default.
• W2022668299 hasConcept C197336794 @default.
• W2022668299 hasConcept C203014093 @default.
• W2022668299 hasConcept C207001950 @default.
• W2022668299 hasConcept C2776964284 @default.
• W2022668299 hasConcept C2779032678 @default.
• W2022668299 hasConcept C33923547 @default.
• W2022668299 hasConcept C542903549 @default.
• W2022668299 hasConcept C55493867 @default.
• W2022668299 hasConcept C557651011 @default.
• W2022668299 hasConcept C71924100 @default.
• W2022668299 hasConcept C86803240 @default.
• W2022668299 hasConceptScore W2022668299C12554922 @default.
• W2022668299 hasConceptScore W2022668299C126838900 @default.
• W2022668299 hasConceptScore W2022668299C134306372 @default.
• W2022668299 hasConceptScore W2022668299C143409427 @default.
• W2022668299 hasConceptScore W2022668299C150903083 @default.
• W2022668299 hasConceptScore W2022668299C159654299 @default.
• W2022668299 hasConceptScore W2022668299C178790620 @default.
• W2022668299 hasConceptScore W2022668299C185592680 @default.
• W2022668299 hasConceptScore W2022668299C192562407 @default.
• W2022668299 hasConceptScore W2022668299C197336794 @default.
• W2022668299 hasConceptScore W2022668299C203014093 @default.
• W2022668299 hasConceptScore W2022668299C207001950 @default.
• W2022668299 hasConceptScore W2022668299C2776964284 @default.
• W2022668299 hasConceptScore W2022668299C2779032678 @default.
• W2022668299 hasConceptScore W2022668299C33923547 @default.
• W2022668299 hasConceptScore W2022668299C542903549 @default.
• W2022668299 hasConceptScore W2022668299C55493867 @default.
• W2022668299 hasConceptScore W2022668299C557651011 @default.
• W2022668299 hasConceptScore W2022668299C71924100 @default.
• W2022668299 hasConceptScore W2022668299C86803240 @default.
• W2022668299 hasIssue "01" @default.
• W2022668299 hasLocation W20226682991 @default.
• W2022668299 hasOpenAccess W2022668299 @default.
• W2022668299 hasPrimaryLocation W20226682991 @default.
• W2022668299 hasRelatedWork W1566089468 @default.
• W2022668299 hasRelatedWork W1971628265 @default.
• W2022668299 hasRelatedWork W2026101545 @default.
• W2022668299 hasRelatedWork W2035407228 @default.
• W2022668299 hasRelatedWork W2067193714 @default.
• W2022668299 hasRelatedWork W2159193724 @default.
• W2022668299 hasRelatedWork W2162597084 @default.
• W2022668299 hasRelatedWork W2410442130 @default.
• W2022668299 hasRelatedWork W2436602471 @default.
• W2022668299 hasRelatedWork W2770508208 @default.
• W2022668299 hasVolume "04" @default.
• W2022668299 isParatext "false" @default.
• W2022668299 isRetracted "false" @default.
• W2022668299 magId "2022668299" @default.

• next