FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022669291> ?p ?o ?g. }

• W2022669291 endingPage "425" @default.
• W2022669291 startingPage "414" @default.
• W2022669291 abstract "Objective The authors evaluated the efficacy of risperidone in reducing psychotic and aggressive symptoms in a subgroup of patients who fulfilled operationalized criteria for psychosis of dementia. Methods Authors conducted a subgroup analysis of patients in the risperidone database arising from a previous double-blind, randomized, placebo-controlled study. In the primary study, patients age 55 or older, with a DSM-IV diagnosis of Alzheimer disease and/or vascular dementia were randomized to placebo or 0.5 mg, 1.0 mg, or 2.0 mg/day of risperidone. For this analysis, patients were selected who fulfilled operationalized criteria for psychosis of dementia. These criteria were then validated. The primary outcome measures were the newly developed Psychosis and Aggression Severity Indices, derived from Parts 1 and 2 of the BEHAVE-AD rating scale. Results At Week 12 and endpoint, patients with psychosis of dementia receiving 1 mg or 2 mg/day of risperidone showed significantly more improvement on the Psychosis Severity and Aggressiveness Severity Indices than those receiving placebo. Conclusions The construct of psychosis of dementia was validated, and the severity of both psychosis and aggressiveness was reduced with risperidone treatment in a robust and dose-related way, with a continuing response over the 12-week trial period. The authors evaluated the efficacy of risperidone in reducing psychotic and aggressive symptoms in a subgroup of patients who fulfilled operationalized criteria for psychosis of dementia. Authors conducted a subgroup analysis of patients in the risperidone database arising from a previous double-blind, randomized, placebo-controlled study. In the primary study, patients age 55 or older, with a DSM-IV diagnosis of Alzheimer disease and/or vascular dementia were randomized to placebo or 0.5 mg, 1.0 mg, or 2.0 mg/day of risperidone. For this analysis, patients were selected who fulfilled operationalized criteria for psychosis of dementia. These criteria were then validated. The primary outcome measures were the newly developed Psychosis and Aggression Severity Indices, derived from Parts 1 and 2 of the BEHAVE-AD rating scale. At Week 12 and endpoint, patients with psychosis of dementia receiving 1 mg or 2 mg/day of risperidone showed significantly more improvement on the Psychosis Severity and Aggressiveness Severity Indices than those receiving placebo. The construct of psychosis of dementia was validated, and the severity of both psychosis and aggressiveness was reduced with risperidone treatment in a robust and dose-related way, with a continuing response over the 12-week trial period." @default.
• W2022669291 created "2016-06-24" @default.
• W2022669291 creator A5016290824 @default.
• W2022669291 creator A5024819513 @default.
• W2022669291 creator A5033574802 @default.
• W2022669291 creator A5039546040 @default.
• W2022669291 creator A5056090615 @default.
• W2022669291 creator A5059020389 @default.
• W2022669291 date "2003-07-01" @default.
• W2022669291 modified "2023-10-16" @default.
• W2022669291 title "Psychosis of Alzheimer Disease: Validity of the Construct and Response to Risperidone" @default.
• W2022669291 cites W1847168837 @default.
• W2022669291 cites W1993818042 @default.
• W2022669291 cites W2088317481 @default.
• W2022669291 cites W2144373877 @default.
• W2022669291 cites W2333793022 @default.
• W2022669291 cites W4245002945 @default.
• W2022669291 doi "https://doi.org/10.1097/00019442-200307000-00004" @default.
• W2022669291 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12837670" @default.
• W2022669291 hasPublicationYear "2003" @default.
• W2022669291 type Work @default.
• W2022669291 sameAs 2022669291 @default.
• W2022669291 citedByCount "34" @default.
• W2022669291 countsByYear W20226692912014 @default.
• W2022669291 countsByYear W20226692912018 @default.
• W2022669291 countsByYear W20226692912019 @default.
• W2022669291 countsByYear W20226692912020 @default.
• W2022669291 countsByYear W20226692912021 @default.
• W2022669291 countsByYear W20226692912022 @default.
• W2022669291 countsByYear W20226692912023 @default.
• W2022669291 crossrefType "journal-article" @default.
• W2022669291 hasAuthorship W2022669291A5016290824 @default.
• W2022669291 hasAuthorship W2022669291A5024819513 @default.
• W2022669291 hasAuthorship W2022669291A5033574802 @default.
• W2022669291 hasAuthorship W2022669291A5039546040 @default.
• W2022669291 hasAuthorship W2022669291A5056090615 @default.
• W2022669291 hasAuthorship W2022669291A5059020389 @default.
• W2022669291 hasConcept C118552586 @default.
• W2022669291 hasConcept C126322002 @default.
• W2022669291 hasConcept C142724271 @default.
• W2022669291 hasConcept C15744967 @default.
• W2022669291 hasConcept C168563851 @default.
• W2022669291 hasConcept C204787440 @default.
• W2022669291 hasConcept C27081682 @default.
• W2022669291 hasConcept C2776412080 @default.
• W2022669291 hasConcept C2778528637 @default.
• W2022669291 hasConcept C2779134260 @default.
• W2022669291 hasConcept C2779483572 @default.
• W2022669291 hasConcept C2779727114 @default.
• W2022669291 hasConcept C2780057945 @default.
• W2022669291 hasConcept C2780494398 @default.
• W2022669291 hasConcept C2780616385 @default.
• W2022669291 hasConcept C70410870 @default.
• W2022669291 hasConcept C71924100 @default.
• W2022669291 hasConceptScore W2022669291C118552586 @default.
• W2022669291 hasConceptScore W2022669291C126322002 @default.
• W2022669291 hasConceptScore W2022669291C142724271 @default.
• W2022669291 hasConceptScore W2022669291C15744967 @default.
• W2022669291 hasConceptScore W2022669291C168563851 @default.
• W2022669291 hasConceptScore W2022669291C204787440 @default.
• W2022669291 hasConceptScore W2022669291C27081682 @default.
• W2022669291 hasConceptScore W2022669291C2776412080 @default.
• W2022669291 hasConceptScore W2022669291C2778528637 @default.
• W2022669291 hasConceptScore W2022669291C2779134260 @default.
• W2022669291 hasConceptScore W2022669291C2779483572 @default.
• W2022669291 hasConceptScore W2022669291C2779727114 @default.
• W2022669291 hasConceptScore W2022669291C2780057945 @default.
• W2022669291 hasConceptScore W2022669291C2780494398 @default.
• W2022669291 hasConceptScore W2022669291C2780616385 @default.
• W2022669291 hasConceptScore W2022669291C70410870 @default.
• W2022669291 hasConceptScore W2022669291C71924100 @default.
• W2022669291 hasIssue "4" @default.
• W2022669291 hasLocation W20226692911 @default.
• W2022669291 hasLocation W20226692912 @default.
• W2022669291 hasOpenAccess W2022669291 @default.
• W2022669291 hasPrimaryLocation W20226692911 @default.
• W2022669291 hasRelatedWork W1964450992 @default.
• W2022669291 hasRelatedWork W2022669291 @default.
• W2022669291 hasRelatedWork W2134430627 @default.
• W2022669291 hasRelatedWork W2291501000 @default.
• W2022669291 hasRelatedWork W2350091651 @default.
• W2022669291 hasRelatedWork W2361465535 @default.
• W2022669291 hasRelatedWork W2363498298 @default.
• W2022669291 hasRelatedWork W2374500742 @default.
• W2022669291 hasRelatedWork W2388619229 @default.
• W2022669291 hasRelatedWork W4231237657 @default.
• W2022669291 hasVolume "11" @default.
• W2022669291 isParatext "false" @default.
• W2022669291 isRetracted "false" @default.
• W2022669291 magId "2022669291" @default.
• W2022669291 workType "article" @default.