FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022673339> ?p ?o ?g. }

• W2022673339 endingPage "3756" @default.
• W2022673339 startingPage "3751" @default.
• W2022673339 abstract "A pilot study was carried out in cattle to determine the immunogenicity of a synthetic consensus peptide comprising the G-H loop region of foot-and-mouth disease virus (FMDV) type-O VP1 and a non-VP1 T-helper (Th) epitope. Cattle vaccinated intramuscularly either once (n = 5) or twice (n = 4) with 50 microg of the peptide preparation at a 21-day interval developed antibodies to the peptide as determined by ELISA with the exception of one steer that received a single dose. However, neutralizing antibody titers against FMDV type-O were modest and all animals presented with clinical FMD signs upon challenge 21 days after the last vaccination. In contrast, four of the five animals inoculated with an inactivated FMD type-O commercially prepared vaccine developed neutralizing antibodies and were fully protected against clinical disease following virus challenge 21 days post-vaccination (dpv). Nucleotide sequence comparison of the VP1 region between the challenge virus and RT-PCR products recovered from a lesion of the peptide-vaccinated animal with the highest neutralizing antibody titer 5 days post-challenge (dpc) showed no evidence for selection of a neutralization-resistant mutant. We conclude that although the synthetic peptide induced an antibody response in cattle, it failed to confer protection against FMDV challenge." @default.
• W2022673339 created "2016-06-24" @default.
• W2022673339 creator A5011805768 @default.
• W2022673339 creator A5021688470 @default.
• W2022673339 creator A5043728649 @default.
• W2022673339 creator A5048978585 @default.
• W2022673339 creator A5054911839 @default.
• W2022673339 creator A5073091105 @default.
• W2022673339 date "2003-09-01" @default.
• W2022673339 modified "2023-09-23" @default.
• W2022673339 title "A synthetic peptide containing the consensus sequence of the G–H loop region of foot-and-mouth disease virus type-O VP1 and a promiscuous T-helper epitope induces peptide-specific antibodies but fails to protect cattle against viral challenge" @default.
• W2022673339 cites W1411119344 @default.
• W2022673339 cites W1558594385 @default.
• W2022673339 cites W1963709479 @default.
• W2022673339 cites W1969963597 @default.
• W2022673339 cites W1984026060 @default.
• W2022673339 cites W1994627586 @default.
• W2022673339 cites W1996956237 @default.
• W2022673339 cites W2032807914 @default.
• W2022673339 cites W2058850752 @default.
• W2022673339 cites W2061193442 @default.
• W2022673339 cites W2068441152 @default.
• W2022673339 cites W2068966036 @default.
• W2022673339 cites W2070486813 @default.
• W2022673339 cites W2071390215 @default.
• W2022673339 cites W2077057923 @default.
• W2022673339 cites W2090734468 @default.
• W2022673339 cites W2092757099 @default.
• W2022673339 cites W2102470809 @default.
• W2022673339 cites W2124220866 @default.
• W2022673339 cites W2136432286 @default.
• W2022673339 cites W2146636778 @default.
• W2022673339 cites W2163410014 @default.
• W2022673339 cites W2202206217 @default.
• W2022673339 doi "https://doi.org/10.1016/s0264-410x(03)00364-5" @default.
• W2022673339 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12922108" @default.
• W2022673339 hasPublicationYear "2003" @default.
• W2022673339 type Work @default.
• W2022673339 sameAs 2022673339 @default.
• W2022673339 citedByCount "64" @default.
• W2022673339 countsByYear W20226733392012 @default.
• W2022673339 countsByYear W20226733392013 @default.
• W2022673339 countsByYear W20226733392014 @default.
• W2022673339 countsByYear W20226733392015 @default.
• W2022673339 countsByYear W20226733392016 @default.
• W2022673339 countsByYear W20226733392017 @default.
• W2022673339 countsByYear W20226733392018 @default.
• W2022673339 countsByYear W20226733392019 @default.
• W2022673339 countsByYear W20226733392020 @default.
• W2022673339 countsByYear W20226733392021 @default.
• W2022673339 countsByYear W20226733392022 @default.
• W2022673339 crossrefType "journal-article" @default.
• W2022673339 hasAuthorship W2022673339A5011805768 @default.
• W2022673339 hasAuthorship W2022673339A5021688470 @default.
• W2022673339 hasAuthorship W2022673339A5043728649 @default.
• W2022673339 hasAuthorship W2022673339A5048978585 @default.
• W2022673339 hasAuthorship W2022673339A5054911839 @default.
• W2022673339 hasAuthorship W2022673339A5073091105 @default.
• W2022673339 hasConcept C159047783 @default.
• W2022673339 hasConcept C159654299 @default.
• W2022673339 hasConcept C195616568 @default.
• W2022673339 hasConcept C203014093 @default.
• W2022673339 hasConcept C22070199 @default.
• W2022673339 hasConcept C22889606 @default.
• W2022673339 hasConcept C2522874641 @default.
• W2022673339 hasConcept C2776151397 @default.
• W2022673339 hasConcept C2776789287 @default.
• W2022673339 hasConcept C2779070877 @default.
• W2022673339 hasConcept C2779102375 @default.
• W2022673339 hasConcept C2779261636 @default.
• W2022673339 hasConcept C2779281246 @default.
• W2022673339 hasConcept C2780868878 @default.
• W2022673339 hasConcept C32611913 @default.
• W2022673339 hasConcept C55493867 @default.
• W2022673339 hasConcept C86803240 @default.
• W2022673339 hasConceptScore W2022673339C159047783 @default.
• W2022673339 hasConceptScore W2022673339C159654299 @default.
• W2022673339 hasConceptScore W2022673339C195616568 @default.
• W2022673339 hasConceptScore W2022673339C203014093 @default.
• W2022673339 hasConceptScore W2022673339C22070199 @default.
• W2022673339 hasConceptScore W2022673339C22889606 @default.
• W2022673339 hasConceptScore W2022673339C2522874641 @default.
• W2022673339 hasConceptScore W2022673339C2776151397 @default.
• W2022673339 hasConceptScore W2022673339C2776789287 @default.
• W2022673339 hasConceptScore W2022673339C2779070877 @default.
• W2022673339 hasConceptScore W2022673339C2779102375 @default.
• W2022673339 hasConceptScore W2022673339C2779261636 @default.
• W2022673339 hasConceptScore W2022673339C2779281246 @default.
• W2022673339 hasConceptScore W2022673339C2780868878 @default.
• W2022673339 hasConceptScore W2022673339C32611913 @default.
• W2022673339 hasConceptScore W2022673339C55493867 @default.
• W2022673339 hasConceptScore W2022673339C86803240 @default.
• W2022673339 hasIssue "25-26" @default.
• W2022673339 hasLocation W20226733391 @default.
• W2022673339 hasLocation W20226733392 @default.
• W2022673339 hasOpenAccess W2022673339 @default.
• W2022673339 hasPrimaryLocation W20226733391 @default.
• W2022673339 hasRelatedWork W1966596277 @default.

• next