Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022677380> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2022677380 abstract "Three-dimensional quantitative structure-activity relationship (3D-QSAR) models were developed for 46 triazafluorenone derivatives, inhibiting metabotropic glutamate receptor subtype 1 (mGluR1). It includes molecular field analysis (MFA) and receptor surface analysis (RSA). The QSAR model was developed using 35 compounds and its predictive ability was assessed using a test set of 11 compounds. The predictive 3D-QSAR models have conventional r(2) values of 0.908 and 0.798 for MFA and RSA, respectively; while the cross-validated coefficient r(cv)(2) values of 0.707 and 0.580 for MFA and RSA, respectively. The results of 3D-QSAR methodologies provide a powerful tool directed to the design of novel and selective triazafluorenone inhibitors." @default.
- W2022677380 created "2016-06-24" @default.
- W2022677380 creator A5017416851 @default.
- W2022677380 creator A5042493377 @default.
- W2022677380 creator A5069242569 @default.
- W2022677380 creator A5070529485 @default.
- W2022677380 creator A5082690877 @default.
- W2022677380 date "2008-05-01" @default.
- W2022677380 modified "2023-09-25" @default.
- W2022677380 title "3D-QSAR studies of triazafluorenone inhibitors of metabotropic glutamate receptor subtype 1" @default.
- W2022677380 cites W1991222835 @default.
- W2022677380 cites W2001311215 @default.
- W2022677380 cites W2002717737 @default.
- W2022677380 cites W2008517160 @default.
- W2022677380 cites W2016413308 @default.
- W2022677380 cites W2019980219 @default.
- W2022677380 cites W2043166209 @default.
- W2022677380 cites W2066439205 @default.
- W2022677380 cites W2087661061 @default.
- W2022677380 cites W2129108032 @default.
- W2022677380 cites W2130227962 @default.
- W2022677380 cites W2132128326 @default.
- W2022677380 cites W2174482126 @default.
- W2022677380 cites W2311816167 @default.
- W2022677380 cites W66730294 @default.
- W2022677380 doi "https://doi.org/10.1016/j.ejmech.2007.06.024" @default.
- W2022677380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17822809" @default.
- W2022677380 hasPublicationYear "2008" @default.
- W2022677380 type Work @default.
- W2022677380 sameAs 2022677380 @default.
- W2022677380 citedByCount "3" @default.
- W2022677380 countsByYear W20226773802015 @default.
- W2022677380 countsByYear W20226773802017 @default.
- W2022677380 crossrefType "journal-article" @default.
- W2022677380 hasAuthorship W2022677380A5017416851 @default.
- W2022677380 hasAuthorship W2022677380A5042493377 @default.
- W2022677380 hasAuthorship W2022677380A5069242569 @default.
- W2022677380 hasAuthorship W2022677380A5070529485 @default.
- W2022677380 hasAuthorship W2022677380A5082690877 @default.
- W2022677380 hasConcept C164126121 @default.
- W2022677380 hasConcept C170493617 @default.
- W2022677380 hasConcept C185592680 @default.
- W2022677380 hasConcept C207951395 @default.
- W2022677380 hasConcept C41653306 @default.
- W2022677380 hasConcept C49051014 @default.
- W2022677380 hasConcept C55493867 @default.
- W2022677380 hasConcept C61174792 @default.
- W2022677380 hasConcept C70721500 @default.
- W2022677380 hasConcept C71240020 @default.
- W2022677380 hasConcept C86803240 @default.
- W2022677380 hasConceptScore W2022677380C164126121 @default.
- W2022677380 hasConceptScore W2022677380C170493617 @default.
- W2022677380 hasConceptScore W2022677380C185592680 @default.
- W2022677380 hasConceptScore W2022677380C207951395 @default.
- W2022677380 hasConceptScore W2022677380C41653306 @default.
- W2022677380 hasConceptScore W2022677380C49051014 @default.
- W2022677380 hasConceptScore W2022677380C55493867 @default.
- W2022677380 hasConceptScore W2022677380C61174792 @default.
- W2022677380 hasConceptScore W2022677380C70721500 @default.
- W2022677380 hasConceptScore W2022677380C71240020 @default.
- W2022677380 hasConceptScore W2022677380C86803240 @default.
- W2022677380 hasLocation W20226773801 @default.
- W2022677380 hasLocation W20226773802 @default.
- W2022677380 hasOpenAccess W2022677380 @default.
- W2022677380 hasPrimaryLocation W20226773801 @default.
- W2022677380 hasRelatedWork W1966912675 @default.
- W2022677380 hasRelatedWork W1979261539 @default.
- W2022677380 hasRelatedWork W1982908217 @default.
- W2022677380 hasRelatedWork W1994207201 @default.
- W2022677380 hasRelatedWork W2002717737 @default.
- W2022677380 hasRelatedWork W2003277205 @default.
- W2022677380 hasRelatedWork W2006235833 @default.
- W2022677380 hasRelatedWork W2039727051 @default.
- W2022677380 hasRelatedWork W2050342815 @default.
- W2022677380 hasRelatedWork W2074753958 @default.
- W2022677380 hasRelatedWork W2088780980 @default.
- W2022677380 hasRelatedWork W2089877233 @default.
- W2022677380 hasRelatedWork W2092747885 @default.
- W2022677380 hasRelatedWork W2095347713 @default.
- W2022677380 hasRelatedWork W2098978690 @default.
- W2022677380 hasRelatedWork W2108363261 @default.
- W2022677380 hasRelatedWork W2140078401 @default.
- W2022677380 hasRelatedWork W2178048878 @default.
- W2022677380 hasRelatedWork W2178789858 @default.
- W2022677380 hasRelatedWork W2180376584 @default.
- W2022677380 isParatext "false" @default.
- W2022677380 isRetracted "false" @default.
- W2022677380 magId "2022677380" @default.
- W2022677380 workType "article" @default.