Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022678399> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2022678399 abstract "The direct effect of methimazole (MMI) on FRTL-5 cell growth was examined. TSH, (Bu)2cAMP, calf serum, insulin-like growth factor I, and Graves' immunoglobulin (IgG) increased [3H]thymidine incorporation into DNA during 72-h incubation. MMI (10(-3) M), which does not damage cell viability, significantly enhanced the increase in [3H]thymidine incorporation induced by TSH and (Bu)2cAMP. In contrast, MMI suppressed the increase in [3H]thymidine incorporation induced by calf serum, insulin-like growth factor I, and Graves' IgG. MMI had no effect on the production of cAMP by TSH. Accordingly, we concluded that MMI has opposite effects on cAMP- and non-cAMP-dependent cell growth pathways. Moreover, Graves' IgG, which has a modest effect on cAMP production, is believed to induce cell growth via the non-cAMP dependent cell growth pathway." @default.
- W2022678399 created "2016-06-24" @default.
- W2022678399 creator A5047323105 @default.
- W2022678399 creator A5068048951 @default.
- W2022678399 creator A5086670547 @default.
- W2022678399 date "1989-05-01" @default.
- W2022678399 modified "2023-09-25" @default.
- W2022678399 title "Direct Effect of Methimazole on Rat Thyroidal Cell Growth Induced by Thyrotropin and Insulin-Like Growth Factor I" @default.
- W2022678399 cites W1949424156 @default.
- W2022678399 cites W1975973643 @default.
- W2022678399 cites W1977053282 @default.
- W2022678399 cites W1998354448 @default.
- W2022678399 cites W2005773030 @default.
- W2022678399 cites W2022787050 @default.
- W2022678399 cites W2030974372 @default.
- W2022678399 cites W2038140715 @default.
- W2022678399 cites W2048510999 @default.
- W2022678399 cites W2050842963 @default.
- W2022678399 cites W2053149611 @default.
- W2022678399 cites W2073523555 @default.
- W2022678399 cites W2088575436 @default.
- W2022678399 cites W2405871957 @default.
- W2022678399 doi "https://doi.org/10.1210/endo-124-5-2046" @default.
- W2022678399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2539965" @default.
- W2022678399 hasPublicationYear "1989" @default.
- W2022678399 type Work @default.
- W2022678399 sameAs 2022678399 @default.
- W2022678399 citedByCount "16" @default.
- W2022678399 crossrefType "journal-article" @default.
- W2022678399 hasAuthorship W2022678399A5047323105 @default.
- W2022678399 hasAuthorship W2022678399A5068048951 @default.
- W2022678399 hasAuthorship W2022678399A5086670547 @default.
- W2022678399 hasConcept C126322002 @default.
- W2022678399 hasConcept C134018914 @default.
- W2022678399 hasConcept C170493617 @default.
- W2022678399 hasConcept C185592680 @default.
- W2022678399 hasConcept C202751555 @default.
- W2022678399 hasConcept C25642318 @default.
- W2022678399 hasConcept C2775960820 @default.
- W2022678399 hasConcept C2776417830 @default.
- W2022678399 hasConcept C2776652619 @default.
- W2022678399 hasConcept C2777108182 @default.
- W2022678399 hasConcept C2777608072 @default.
- W2022678399 hasConcept C2779306644 @default.
- W2022678399 hasConcept C2780689927 @default.
- W2022678399 hasConcept C526584372 @default.
- W2022678399 hasConcept C55493867 @default.
- W2022678399 hasConcept C62112901 @default.
- W2022678399 hasConcept C64241487 @default.
- W2022678399 hasConcept C71924100 @default.
- W2022678399 hasConcept C80862487 @default.
- W2022678399 hasConcept C86803240 @default.
- W2022678399 hasConceptScore W2022678399C126322002 @default.
- W2022678399 hasConceptScore W2022678399C134018914 @default.
- W2022678399 hasConceptScore W2022678399C170493617 @default.
- W2022678399 hasConceptScore W2022678399C185592680 @default.
- W2022678399 hasConceptScore W2022678399C202751555 @default.
- W2022678399 hasConceptScore W2022678399C25642318 @default.
- W2022678399 hasConceptScore W2022678399C2775960820 @default.
- W2022678399 hasConceptScore W2022678399C2776417830 @default.
- W2022678399 hasConceptScore W2022678399C2776652619 @default.
- W2022678399 hasConceptScore W2022678399C2777108182 @default.
- W2022678399 hasConceptScore W2022678399C2777608072 @default.
- W2022678399 hasConceptScore W2022678399C2779306644 @default.
- W2022678399 hasConceptScore W2022678399C2780689927 @default.
- W2022678399 hasConceptScore W2022678399C526584372 @default.
- W2022678399 hasConceptScore W2022678399C55493867 @default.
- W2022678399 hasConceptScore W2022678399C62112901 @default.
- W2022678399 hasConceptScore W2022678399C64241487 @default.
- W2022678399 hasConceptScore W2022678399C71924100 @default.
- W2022678399 hasConceptScore W2022678399C80862487 @default.
- W2022678399 hasConceptScore W2022678399C86803240 @default.
- W2022678399 hasLocation W20226783991 @default.
- W2022678399 hasLocation W20226783992 @default.
- W2022678399 hasOpenAccess W2022678399 @default.
- W2022678399 hasPrimaryLocation W20226783991 @default.
- W2022678399 hasRelatedWork W1975650642 @default.
- W2022678399 hasRelatedWork W2014116250 @default.
- W2022678399 hasRelatedWork W2022678399 @default.
- W2022678399 hasRelatedWork W2030221698 @default.
- W2022678399 hasRelatedWork W2051039150 @default.
- W2022678399 hasRelatedWork W2053449558 @default.
- W2022678399 hasRelatedWork W2070160241 @default.
- W2022678399 hasRelatedWork W2070831900 @default.
- W2022678399 hasRelatedWork W2079251901 @default.
- W2022678399 hasRelatedWork W2130332764 @default.
- W2022678399 isParatext "false" @default.
- W2022678399 isRetracted "false" @default.
- W2022678399 magId "2022678399" @default.
- W2022678399 workType "article" @default.